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B5BJG9

- RHAR_SALPK

UniProt

B5BJG9 - RHAR_SALPK

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Protein
HTH-type transcriptional activator RhaR
Gene
rhaR, SSPA3620
Organism
Salmonella paratyphi A (strain AKU_12601)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Activates expression of the rhaSR operon in response to L-rhamnose By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei246 – 2461Interaction with sigma-70 By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi195 – 21420H-T-H motif By similarity
Add
BLAST
DNA bindingi244 – 26724H-T-H motif By similarity
Add
BLAST

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. positive regulation of transcription, DNA-templated Source: UniProtKB-HAMAP
  2. rhamnose metabolic process Source: UniProtKB-HAMAP
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Rhamnose metabolism, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciSENT554290:GJDA-3899-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional activator RhaR
Alternative name(s):
L-rhamnose operon transcriptional activator RhaR
Gene namesi
Name:rhaR
Ordered Locus Names:SSPA3620
OrganismiSalmonella paratyphi A (strain AKU_12601)
Taxonomic identifieri554290 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001869: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 282282HTH-type transcriptional activator RhaRUniRule annotation
PRO_1000200943Add
BLAST

Proteomic databases

PRIDEiB5BJG9.

Interactioni

Subunit structurei

Binds DNA as a dimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi554290.SSPA3620.

Structurei

3D structure databases

ProteinModelPortaliB5BJG9.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG2207.
HOGENOMiHOG000290513.
OMAiLQTEDYF.
OrthoDBiEOG6Z3KH4.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
2.60.120.280. 1 hit.
HAMAPiMF_01533. HTH_type_RhaR.
InterProiIPR003313. AraC-bd.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR011051. RmlC_Cupin.
IPR023699. Tscrpt_act_RhaR.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF02311. AraC_binding. 1 hit.
PF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF51182. SSF51182. 1 hit.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5BJG9-1 [UniParc]FASTAAdd to Basket

« Hide

MANQLILLKK DFFTDEQQAV TVADRYPQDV FAEHTHEFCE LVMVWRGNGL    50
HVLNERPYRI TRGDLFYIRA EDKHSYTSVN DLVLQNIIYC PERLKLNVNW 100
QAMIPGFQGA QWHPHWRLGS MGMNQARQVI NQLEHESNGR DPLANEMAEL 150
LFGQLVMTLK RHRYATDDLP ATSRETLLDK LITALANSLE CPFALDAFCQ 200
QEQCSERVLR QQFRAQTGMT INQYLRQVRI CHAQYLLQHS PLMISEISMQ 250
CGFEDSNYFS VVFTRETGMT PSQWRHLSNQ SD 282
Length:282
Mass (Da):32,858
Last modified:September 23, 2008 - v1
Checksum:i657BF8FE7DE1CF20
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM200053 Genomic DNA. Translation: CAR61902.1.
RefSeqiYP_002144461.1. NC_011147.1.

Genome annotation databases

EnsemblBacteriaiCAR61902; CAR61902; SSPA3620.
PATRICi32347932. VBISalEnt134303_4139.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM200053 Genomic DNA. Translation: CAR61902.1 .
RefSeqi YP_002144461.1. NC_011147.1.

3D structure databases

ProteinModelPortali B5BJG9.
ModBasei Search...

Protein-protein interaction databases

STRINGi 554290.SSPA3620.

Protein family/group databases

AraC-XylS Search...

Proteomic databases

PRIDEi B5BJG9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR61902 ; CAR61902 ; SSPA3620 .
PATRICi 32347932. VBISalEnt134303_4139.

Phylogenomic databases

eggNOGi COG2207.
HOGENOMi HOG000290513.
OMAi LQTEDYF.
OrthoDBi EOG6Z3KH4.

Enzyme and pathway databases

BioCyci SENT554290:GJDA-3899-MONOMER.

Family and domain databases

Gene3Di 1.10.10.60. 2 hits.
2.60.120.280. 1 hit.
HAMAPi MF_01533. HTH_type_RhaR.
InterProi IPR003313. AraC-bd.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR011051. RmlC_Cupin.
IPR023699. Tscrpt_act_RhaR.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view ]
Pfami PF02311. AraC_binding. 1 hit.
PF12833. HTH_18. 1 hit.
[Graphical view ]
PRINTSi PR00032. HTHARAC.
SMARTi SM00342. HTH_ARAC. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
SSF51182. SSF51182. 1 hit.
PROSITEi PS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Pseudogene accumulation in the evolutionary histories of Salmonella enterica serovars Paratyphi A and Typhi."
    Holt K.E., Thomson N.R., Wain J., Langridge G.C., Hasan R., Bhutta Z.A., Quail M.A., Norbertczak H., Walker D., Simmonds M., White B., Bason N., Mungall K., Dougan G., Parkhill J.
    BMC Genomics 10:36-36(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AKU_12601.

Entry informationi

Entry nameiRHAR_SALPK
AccessioniPrimary (citable) accession number: B5BJG9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: May 14, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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