Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

2,3-bisphosphoglycerate-independent phosphoglycerate mutase

Gene

gpmI

Organism
Salmonella paratyphi A (strain AKU_12601)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.UniRule annotationSAAS annotation

Catalytic activityi

2-phospho-D-glycerate = 3-phospho-D-glycerate.UniRule annotationSAAS annotation

Cofactori

Protein has several cofactor binding sites:
  • Mn2+UniRule annotationSAAS annotationNote: Binds 2 manganese ions per subunit.UniRule annotationSAAS annotation
  • Mn2+Note: Binds 2 manganese ions per subunit.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi7 – 71Manganese 2UniRule annotation
Active sitei57 – 571Phosphoserine intermediateUniRule annotation
Metal bindingi57 – 571Manganese 2UniRule annotation
Metal bindingi396 – 3961Manganese 1UniRule annotation
Metal bindingi400 – 4001Manganese 1UniRule annotation
Metal bindingi437 – 4371Manganese 2UniRule annotation
Metal bindingi438 – 4381Manganese 2UniRule annotation
Metal bindingi456 – 4561Manganese 1UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ManganeseUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciSENT554290:GJDA-3564-MONOMER.
UniPathwayiUPA00109; UER00186.

Names & Taxonomyi

Protein namesi
Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutaseUniRule annotationSAAS annotation (EC:5.4.2.12UniRule annotationSAAS annotation)
Short name:
BPG-independent PGAMUniRule annotation
Short name:
PhosphoglyceromutaseUniRule annotation
Short name:
iPGMUniRule annotation
Gene namesi
Name:gpmIUniRule annotation
Ordered Locus Names:SSPA3319Imported
OrganismiSalmonella paratyphi A (strain AKU_12601)Imported
Taxonomic identifieri554290 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001869 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi554290.SSPA3319.

Structurei

3D structure databases

ProteinModelPortaliB5BHY7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BPG-independent phosphoglycerate mutase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0696.
HOGENOMiHOG000223664.
OMAiDEFIMPA.
OrthoDBiEOG6HJ22X.

Family and domain databases

Gene3Di3.40.1450.10. 1 hit.
3.40.720.10. 2 hits.
HAMAPiMF_01038. GpmI.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR011258. BPG-indep_PGM_N.
IPR006124. Metalloenzyme.
IPR005995. Pgm_bpd_ind.
[Graphical view]
PfamiPF06415. iPGM_N. 1 hit.
PF01676. Metalloenzyme. 1 hit.
[Graphical view]
PIRSFiPIRSF001492. IPGAM. 1 hit.
SUPFAMiSSF53649. SSF53649. 2 hits.
SSF64158. SSF64158. 1 hit.
TIGRFAMsiTIGR01307. pgm_bpd_ind. 1 hit.

Sequencei

Sequence statusi: Complete.

B5BHY7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLVILDGYG YREEQQDNAI LNAKTPVMDA LWAKRPHTLI DASGLEVGLP
60 70 80 90 100
DRQMGNSEVG HVNLGAGRIV YQDLTRLDVE IKERTFFANP VLTNAVDQAK
110 120 130 140 150
NAGKAVHIMG LLSAGGVHSH EDHIMAMVEL AAERGAEKIY LHAFLDGRDT
160 170 180 190 200
PPRSAEASLK KFEDKFAALG KGRVASIVGR YYAMDRDNRW DRVEKAYDLM
210 220 230 240 250
TLAQGEFQAD TAVAGLQAAY ARDENDEFVK ATVIRAEGQA DAAMEDGDTL
260 270 280 290 300
IFMNFRADRA REITRAFVNA DFDGFARKKV VNLNFVMLTE YAADIKTAVA
310 320 330 340 350
YPPASLANTF GEWMAKNDKT QLRISETEKY AHVTFFFNGG VEEPFAGEER
360 370 380 390 400
ILINSPKVAT YDLQPEMSSA ELTEKLVAAI ESGKYDTIIC NYPNGDMVGH
410 420 430 440 450
TGVMEAAIKA VEALDNCIEQ VTKAVESVGG QLLITADHGN AEQMRDPATG
460 470 480 490 500
QAHTAHTNLP VPLIYVGEKN VKAVEGGKLS DIAPTMLSLM GMEIPQEMTG

KPLFIVE
Length:507
Mass (Da):55,497
Last modified:September 23, 2008 - v1
Checksum:i96F6B95A297D4123
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM200053 Genomic DNA. Translation: CAR61585.1.
RefSeqiWP_011233202.1. NC_011147.1.
YP_002144158.1. NC_011147.1.

Genome annotation databases

EnsemblBacteriaiCAR61585; CAR61585; SSPA3319.
PATRICi32347201. VBISalEnt134303_3790.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM200053 Genomic DNA. Translation: CAR61585.1.
RefSeqiWP_011233202.1. NC_011147.1.
YP_002144158.1. NC_011147.1.

3D structure databases

ProteinModelPortaliB5BHY7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi554290.SSPA3319.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAR61585; CAR61585; SSPA3319.
PATRICi32347201. VBISalEnt134303_3790.

Phylogenomic databases

eggNOGiCOG0696.
HOGENOMiHOG000223664.
OMAiDEFIMPA.
OrthoDBiEOG6HJ22X.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00186.
BioCyciSENT554290:GJDA-3564-MONOMER.

Family and domain databases

Gene3Di3.40.1450.10. 1 hit.
3.40.720.10. 2 hits.
HAMAPiMF_01038. GpmI.
InterProiIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR011258. BPG-indep_PGM_N.
IPR006124. Metalloenzyme.
IPR005995. Pgm_bpd_ind.
[Graphical view]
PfamiPF06415. iPGM_N. 1 hit.
PF01676. Metalloenzyme. 1 hit.
[Graphical view]
PIRSFiPIRSF001492. IPGAM. 1 hit.
SUPFAMiSSF53649. SSF53649. 2 hits.
SSF64158. SSF64158. 1 hit.
TIGRFAMsiTIGR01307. pgm_bpd_ind. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Pseudogene accumulation in the evolutionary histories of Salmonella enterica serovars Paratyphi A and Typhi."
    Holt K.E., Thomson N.R., Wain J., Langridge G.C., Hasan R., Bhutta Z.A., Quail M.A., Norbertczak H., Walker D., Simmonds M., White B., Bason N., Mungall K., Dougan G., Parkhill J.
    BMC Genomics 10:36-36(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AKU_12601Imported.

Entry informationi

Entry nameiB5BHY7_SALPK
AccessioniPrimary (citable) accession number: B5BHY7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: April 29, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.