Skip Header

Contribute Send feedback
Read comments (?) or add your own

B5BFP4 (B5BFP4_SALPK) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Biosynthetic arginine decarboxylase HAMAP-Rule MF_01417
Short name=ADC HAMAP-Rule MF_01417
EC=4.1.1.19 HAMAP-Rule MF_01417
Gene names
Name:speA HAMAP-Rule MF_01417
Ordered Locus Names:SSPA2749 EMBL CAR60990.1
OrganismSalmonella paratyphi A (strain AKU_12601) [Complete proteome] [HAMAP] EMBL CAR60990.1
Taxonomic identifier554290 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella ›

Protein attributes

Sequence length637 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the biosynthesis of agmatine from arginine By similarity. HAMAP-Rule MF_01417

Catalytic activity

L-arginine = agmatine + CO2. HAMAP-Rule MF_01417 SAAS SAAS022644 RuleBase RU003740

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01417 RuleBase RU003740 SAAS SAAS022644

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01417 SAAS SAAS022644

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1. HAMAP-Rule MF_01417

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily. HAMAP-Rule MF_01417

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region286 – 29611Substrate-binding By similarity HAMAP-Rule MF_01417

Amino acid modifications

Modified residue1061N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01417

Sequences

Sequence LengthMass (Da)Tools
B5BFP4 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 5FA8AADAD494B0FE

FASTA63771,750
        10         20         30         40         50         60 
MQEVAMSSQE ASKMLRTYNI AWWGNNYYDV NELGHISVCP DPDVPEARVD LAKLVKAREA 

        70         80         90        100        110        120 
QGQRLPALFC FPQILQHRLR SINAAFKRAR ESYGYNGDYF LVYPIKVNQH RRVIESLIHS 

       130        140        150        160        170        180 
GEPLGLEAGS KAELMAVLAH AGMTRSVIVC NGYKDREYIR LALIGEKMGH KVYLVIEKMS 

       190        200        210        220        230        240 
EIAIVLEEAE RLNVVPRLGV RARLASQGSG KWQSSGGEKS KFGLAATQVL QLVETLRDAG 

       250        260        270        280        290        300 
RLDSLQLLHF HLGSQMANIR DIATGVRESA RFYVELHKLG VNIQCFDVGG GLGVDYEGTR 

       310        320        330        340        350        360 
SQSDCSVNYG LNEYANNIIW AIGDACEEHG LPHPTVITES GRAVTAHHTV LVSNIIGVER 

       370        380        390        400        410        420 
NEYTDPTAPA EDAPRALQNL WETWQEMHKP GTRRSLREWL HDSQMDLHDI HIGYSSGVFS 

       430        440        450        460        470        480 
LQERAWAEQL YLSMCHEVQK QLDPQNRAHR PIIDELQERM ADKMYVNFSL FQSMPDAWGI 

       490        500        510        520        530        540 
DQLFPVLPLE GLDQVPERRA VLLDITCDSD GAIDHYIDGD GIATTMPMPE YDPENPPMLG 

       550        560        570        580        590        600 
FFMVGAYQEI LGNMHNLFGD TEAVDVFVFP DGSVEVELSD EGDTVADMLQ YVQLDPKTLL 

       610        620        630 
THFRDQVKQT DLDDALQQQF LEEFEAGLYG YTYLEDE

« Hide

References

[1]"Complete genome of a clinical isolate of Salmonella enterica serovar Paratyphi A."
Holt K.E., Thomson N.R., Wain J., Langridge G.C., Hassan R., Bhutta Z., Quail M., Norbertczak H., Danielle W., Simmonds M., White B., Bason N., Mungall K., Dougan G., Parkhill J.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AKU_12601.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FM200053 Genomic DNA. Translation: CAR60990.1.
RefSeqYP_002143591.2. NC_011147.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING554290.SSPA2749.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAR60990; CAR60990; SSPA2749.
GeneID6812089.
KEGGsek:SSPA2749.
PATRIC32345882. VBISalEnt134303_3143.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1166.
HOGENOMHOG000029191.
KOK01585.
OMAMIHFHIG.
ProtClustDBPRK05354.

Enzyme and pathway databases

BioCycSENT554290:GJDA-2954-MONOMER.
UniPathwayUPA00186; UER00284.

Family and domain databases

Gene3D2.40.37.10. 2 hits.
HAMAPMF_01417. SpeA.
InterProIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR022653. De-COase2_pyr-phos_BS.
IPR000183. Orn/DAP/Arg_de-COase.
[Graphical view]
PANTHERPTHR11482:SF3. PTHR11482:SF3. 1 hit.
PfamPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR01273. speA. 1 hit.
PROSITEPS00878. ODR_DC_2_1. 1 hit.
PS00879. ODR_DC_2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB5BFP4_SALPK
AccessionPrimary (citable) accession number: B5BFP4
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info