Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B5BD82

- CLPX_SALPK

UniProt

B5BD82 - CLPX_SALPK

Protein

ATP-dependent Clp protease ATP-binding subunit ClpX

Gene

clpX

Organism
Salmonella paratyphi A (strain AKU_12601)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri15 – 4026C4-typeUniRule annotationAdd
    BLAST
    Nucleotide bindingi120 – 1278ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. nucleoside-triphosphatase activity Source: InterPro
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. protein folding Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Chaperone

    Keywords - Ligandi

    ATP-binding, Metal-binding, Nucleotide-binding, Zinc

    Enzyme and pathway databases

    BioCyciSENT554290:GJDA-2265-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    ATP-dependent Clp protease ATP-binding subunit ClpXUniRule annotation
    Gene namesi
    Name:clpXUniRule annotation
    Ordered Locus Names:SSPA2115
    OrganismiSalmonella paratyphi A (strain AKU_12601)
    Taxonomic identifieri554290 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000001869: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 423423ATP-dependent Clp protease ATP-binding subunit ClpXPRO_1000097999Add
    BLAST

    Proteomic databases

    PRIDEiB5BD82.

    Interactioni

    Subunit structurei

    Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.UniRule annotation

    Protein-protein interaction databases

    STRINGi554290.SSPA2115.

    Structurei

    3D structure databases

    ProteinModelPortaliB5BD82.
    SMRiB5BD82. Positions 9-52.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ClpX chaperone family.UniRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri15 – 4026C4-typeUniRule annotationAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    eggNOGiCOG1219.
    HOGENOMiHOG000010093.
    OMAiILLDIMY.
    OrthoDBiEOG625JZK.

    Family and domain databases

    Gene3Di3.40.50.300. 2 hits.
    HAMAPiMF_00175. ClpX.
    InterProiIPR003593. AAA+_ATPase.
    IPR003959. ATPase_AAA_core.
    IPR019489. Clp_ATPase_C.
    IPR004487. Clp_protease_ATP-bd_su_ClpX.
    IPR027417. P-loop_NTPase.
    IPR010603. Znf_CppX_C4.
    [Graphical view]
    PfamiPF07724. AAA_2. 1 hit.
    PF10431. ClpB_D2-small. 1 hit.
    PF06689. zf-C4_ClpX. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    SM01086. ClpB_D2-small. 1 hit.
    SM00994. zf-C4_ClpX. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00382. clpX. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B5BD82-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTDKRKDGSG KLLYCSFCGK SQHEVRKLIA GPSVYICDEC VDLCNDIIRE    50
    EIKEVAPHRE RSALPTPHEI RTHLDDYVIG QEQAKKVLAV AVYNHYKRLR 100
    NGDTSNGVEL GKSNILLIGP TGSGKTLLAE TLARLLDVPF TMADATTLTE 150
    AGYVGEDVEN IIQKLLQKCD YDVQKAQRGI VYIDEIDKIS RKSDNPSITR 200
    DVSGEGVQQA LLKLIEGTVA AVPPQGGRKH PQQEFLQVDT SKILFICGGA 250
    FAGLDKVIAN RVETGSGIGF GATVKAKSDK ASEGELLSQV EPEDLIKFGL 300
    IPEFIGRLPV VATLNELSEE ALIQILKEPK NALTKQYQAL FNLEGVDLEF 350
    RDEALDAIAR KAMARKTGAR GLRSIVEAAL LDTMYDLPSM EDVEKVVIDE 400
    SVIAGQSKPL LIYGKPEAQA SGE 423
    Length:423
    Mass (Da):46,176
    Last modified:September 23, 2008 - v1
    Checksum:iDBA2250FC755B2D9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FM200053 Genomic DNA. Translation: CAR60325.1.
    RefSeqiYP_002142952.1. NC_011147.1.

    Genome annotation databases

    EnsemblBacteriaiCAR60325; CAR60325; SSPA2115.
    PATRICi32344409. VBISalEnt134303_2421.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FM200053 Genomic DNA. Translation: CAR60325.1 .
    RefSeqi YP_002142952.1. NC_011147.1.

    3D structure databases

    ProteinModelPortali B5BD82.
    SMRi B5BD82. Positions 9-52.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 554290.SSPA2115.

    Proteomic databases

    PRIDEi B5BD82.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAR60325 ; CAR60325 ; SSPA2115 .
    PATRICi 32344409. VBISalEnt134303_2421.

    Phylogenomic databases

    eggNOGi COG1219.
    HOGENOMi HOG000010093.
    OMAi ILLDIMY.
    OrthoDBi EOG625JZK.

    Enzyme and pathway databases

    BioCyci SENT554290:GJDA-2265-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 2 hits.
    HAMAPi MF_00175. ClpX.
    InterProi IPR003593. AAA+_ATPase.
    IPR003959. ATPase_AAA_core.
    IPR019489. Clp_ATPase_C.
    IPR004487. Clp_protease_ATP-bd_su_ClpX.
    IPR027417. P-loop_NTPase.
    IPR010603. Znf_CppX_C4.
    [Graphical view ]
    Pfami PF07724. AAA_2. 1 hit.
    PF10431. ClpB_D2-small. 1 hit.
    PF06689. zf-C4_ClpX. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    SM01086. ClpB_D2-small. 1 hit.
    SM00994. zf-C4_ClpX. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00382. clpX. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Pseudogene accumulation in the evolutionary histories of Salmonella enterica serovars Paratyphi A and Typhi."
      Holt K.E., Thomson N.R., Wain J., Langridge G.C., Hasan R., Bhutta Z.A., Quail M.A., Norbertczak H., Walker D., Simmonds M., White B., Bason N., Mungall K., Dougan G., Parkhill J.
      BMC Genomics 10:36-36(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AKU_12601.

    Entry informationi

    Entry nameiCLPX_SALPK
    AccessioniPrimary (citable) accession number: B5BD82
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3