Reviewed, UniProtKB/Swiss-Prot B5BC39 (6PGL_SALPK)

Names and origin

Protein names

Recommended name:
    6-phosphogluconolactonase
      Short name=6-P-gluconolactonase
    EC=3.1.1.31

Gene names

Name:	pgl
Ordered Locus Names:	SSPA1834

Organism

Salmonella paratyphi A (strain AKU_12601) [Complete proteome] [HAMAP]

Taxonomic identifier

554290 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity.
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605
Sequence similarities	Belongs to the cycloisomerase 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	6-phosphogluconolactonase HAMAP MF_01605		PRO_1000148167

Sequences

	Sequence		Length	Mass (Da)
	B5BC39-1 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 84BAF66E97012D13	FASTA	331	36,351
	10 20 30 40 50 60 MKQTVYTASP ESQQIHVWSL NHEGTLTLVQ VVDVPGQVQP MVVSPDKRYL YVGVRPEFRV 70 80 90 100 110 120 LAYRIAPDDG ALTFAAESAL PGSPTHISTD HHGRFVFVGS YNAGNVSVTR LQDGLPVELV 130 140 150 160 170 180 DVVEGLDGCH SANITPDNRT LWVPALKQER ICLFTLSDDG HLVAQEPAEV NTVEGAGPRH 190 200 210 220 230 240 MVFHPNRQYA YCVNELNSSV DVWQLKNPHG EIECVQTLDM MPADFSDTRW AADIHITPDG 250 260 270 280 290 300 RHLYACDRTA SLITVFSVSE DGSVLSVEGF QPTEAQPRGF NIDNSGKYLI AAGQKSHHIA 310 320 330 VYEITGTQGL LTEKGRYAVG QGPMWVVVNA Y

References

[1]

"Complete genome of a clinical isolate of Salmonella enterica serovar Paratyphi A." Holt K.E., Thomson N.R., Wain J., Langridge G.C., Hassan R., Bhutta Z., Quail M., Norbertczak H., Danielle W., Simmonds M., White B., Bason N., Mungall K., Dougan G., Parkhill J. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	FM200053 Genomic DNA. Translation: CAR60031.1.
RefSeq	YP_002142671.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6811146.
GenomeReviews	Gene locus SSPA1834 in contig FM200053_GR.
KEGG	sek:SSPA1834.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EGCHSAN.
Family and domain databases
HAMAP	MF_01605. [Tree]
InterPro	IPR019405. DUF2394. IPR015943. WD40/YVTN_repeat-like_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
Pfam	PF10282. DUF2394. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

6PGL_SALPK

Accession

Primary (citable) accession number: B5BC39

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	September 23, 2008
Last modified:	November 3, 2009
This is version 8 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)