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Protein
Submitted name:

POU class 5 homeobox 1

Gene

POU5F1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
POU class 5 homeobox 1Imported
Gene namesi
Name:POU5F1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Expressioni

Gene expression databases

BgeeiB5B8P8.
ExpressionAtlasiB5B8P8. baseline.

Family & Domainsi

Keywords - Domaini

HomeoboxImported

Family and domain databases

Gene3Di1.10.260.40. 1 hit.
InterProiIPR010982. Lambda_DNA-bd_dom.
IPR015585. POU_dom_5.
IPR000327. POU_specific.
[Graphical view]
PANTHERiPTHR11636:SF15. PTHR11636:SF15. 1 hit.
PfamiPF00157. Pou. 1 hit.
[Graphical view]
SUPFAMiSSF47413. SSF47413. 1 hit.
PROSITEiPS51179. POU_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B5B8P8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PGGPGIGPGV GPGSEVWGIP PCPPPYEFCG GMAYCGPQVG VGLVPQGGLE
60 70 80 90 100
TSQPEGEAGV GVESNSDGAS PEPCTVTPGA VKLEKEKLEQ NPEESQDIKA
110 120
LQKELEQFAK LLKQKRITLG YTQADV
Length:126
Mass (Da):12,988
Last modified:September 22, 2008 - v1
Checksum:iF5F29BF45C7ADA8F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei126 – 1261Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM177962 mRNA. Translation: CAQ76279.1.
UniGeneiHs.249184.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM177962 mRNA. Translation: CAQ76279.1.
UniGeneiHs.249184.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

NextBioi35477863.

Gene expression databases

BgeeiB5B8P8.
ExpressionAtlasiB5B8P8. baseline.

Family and domain databases

Gene3Di1.10.260.40. 1 hit.
InterProiIPR010982. Lambda_DNA-bd_dom.
IPR015585. POU_dom_5.
IPR000327. POU_specific.
[Graphical view]
PANTHERiPTHR11636:SF15. PTHR11636:SF15. 1 hit.
PfamiPF00157. Pou. 1 hit.
[Graphical view]
SUPFAMiSSF47413. SSF47413. 1 hit.
PROSITEiPS51179. POU_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Oostendorp R.A.
    Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "In-vivo osteoprogenitor potency of human stromal cells from different tissues does not correlate with expression of POU5F1 or its pseudogenes."
    Kaltz N., Funari A., Hippauf S., Delorme D., Noel D., Rimminuci M., Jacobs RA V.R., Haupl T., Jorgensen C., Charbord P., Peschel C., Bianco P., Oostendorp R.A.J.
    Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiB5B8P8_HUMAN
AccessioniPrimary (citable) accession number: B5B8P8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 22, 2008
Last sequence update: September 22, 2008
Last modified: October 28, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.