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B5B850

- B5B850_PANTR

UniProt

B5B850 - B5B850_PANTR

Protein
Submitted name:

Oligoadenylate synthetase 1

Gene

oas1

Organism
Pan troglodytes troglodytes
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 2'-5'-oligoadenylate synthetase activity Source: UniProtKB
    2. ATP binding Source: InterPro
    3. double-stranded RNA binding Source: InterPro
    4. zinc ion binding Source: UniProtKB

    GO - Biological processi

    1. cellular response to interferon-alpha Source: UniProtKB
    2. defense response to virus Source: UniProtKB
    3. immune response Source: InterPro
    4. negative regulation of viral genome replication Source: UniProtKB
    5. purine nucleotide biosynthetic process Source: UniProtKB
    6. regulation of ribonuclease activity Source: UniProtKB

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Oligoadenylate synthetase 1Imported
    Gene namesi
    Name:oas1Imported
    OrganismiPan troglodytes troglodytesImported
    Taxonomic identifieri37011 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB
    2. nucleus Source: UniProtKB

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG000994.

    Family and domain databases

    Gene3Di1.10.1410.20. 1 hit.
    InterProiIPR006117. 2-5-oligoadenylate_synth_CS.
    IPR006116. 2-5-oligoadenylate_synth_N.
    IPR018952. 2-5-oligoAdlate_synth_1_dom2/C.
    IPR026774. 2-5A_synthase.
    IPR002934. Nucleotidyltransferase.
    [Graphical view]
    PANTHERiPTHR11258. PTHR11258. 1 hit.
    PfamiPF01909. NTP_transf_2. 1 hit.
    PF10421. OAS1_C. 1 hit.
    [Graphical view]
    PROSITEiPS00832. 25A_SYNTH_1. 1 hit.
    PS00833. 25A_SYNTH_2. 1 hit.
    PS50152. 25A_SYNTH_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B5B850-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMDLRNTPAK SLDKFIEDYL LPDTCFRMQI NHAIDIICGF LKERCFRGSS    50
    YPVCVSKVVK GGSSGKGTTL RGRSDADLVV FLSPLTTFQD QLNRRGEFIQ 100
    EIRRQLEACQ REERAFSVKF EVQAPRRDNP RALSFVLSSL QLGEGVEFDV 150
    LPAFDALGQL TGGYKPDPQI YVKLIEECTY LQKEGEFSTC FTELQRDFLK 200
    ERPTKLKSLI RLVKHWYQNC KKKLGKLPPQ YALELLTVYA WERGSMKTHF 250
    NTAQGFRTVL ELVINYQQLC IYWTKYYDFK NPIIEKYLSR QLEKPRPVIL 300
    DPADPTGNLG GGDPKGWRQL AQEAEAWLNY PCFKNWDGSP VSSWILLVRP 350
    PASSLPFIPA PLHEA 365
    Length:365
    Mass (Da):41,906
    Last modified:September 23, 2008 - v1
    Checksum:iB943690F270057BE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FM163425 Genomic DNA. Translation: CAQ57746.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FM163425 Genomic DNA. Translation: CAQ57746.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG000994.

    Family and domain databases

    Gene3Di 1.10.1410.20. 1 hit.
    InterProi IPR006117. 2-5-oligoadenylate_synth_CS.
    IPR006116. 2-5-oligoadenylate_synth_N.
    IPR018952. 2-5-oligoAdlate_synth_1_dom2/C.
    IPR026774. 2-5A_synthase.
    IPR002934. Nucleotidyltransferase.
    [Graphical view ]
    PANTHERi PTHR11258. PTHR11258. 1 hit.
    Pfami PF01909. NTP_transf_2. 1 hit.
    PF10421. OAS1_C. 1 hit.
    [Graphical view ]
    PROSITEi PS00832. 25A_SYNTH_1. 1 hit.
    PS00833. 25A_SYNTH_2. 1 hit.
    PS50152. 25A_SYNTH_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Ferguson W.G.
      Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: LeeImported.
    2. "Long-Term Balancing Selection at the Antiviral Gene OAS1 in Central African Chimpanzees."
      Ferguson W., Dvora S., Fikes R.W., Stone A.C., Boissinot S.
      Mol. Biol. Evol. 29:1093-1103(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: LeeImported.

    Entry informationi

    Entry nameiB5B850_PANTR
    AccessioniPrimary (citable) accession number: B5B850
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)