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B5B850

- B5B850_PANTR

UniProt

B5B850 - B5B850_PANTR

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Protein
Submitted name: Oligoadenylate synthetase 1
Gene
oas1
Organism
Pan troglodytes troglodytes
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. 2'-5'-oligoadenylate synthetase activity Source: UniProtKB
  2. ATP binding Source: InterPro
  3. double-stranded RNA binding Source: InterPro
  4. zinc ion binding Source: UniProtKB

GO - Biological processi

  1. cellular response to interferon-alpha Source: UniProtKB
  2. defense response to virus Source: UniProtKB
  3. immune response Source: InterPro
  4. negative regulation of viral genome replication Source: UniProtKB
  5. purine nucleotide biosynthetic process Source: UniProtKB
  6. regulation of ribonuclease activity Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Oligoadenylate synthetase 1Imported
Gene namesi
Name:oas1Imported
OrganismiPan troglodytes troglodytesImported
Taxonomic identifieri37011 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB
  2. nucleus Source: UniProtKB
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG000994.

Family and domain databases

Gene3Di1.10.1410.20. 1 hit.
InterProiIPR006117. 2-5-oligoadenylate_synth_CS.
IPR006116. 2-5-oligoadenylate_synth_N.
IPR018952. 2-5-oligoAdlate_synth_1_dom2/C.
IPR026774. 2-5A_synthase.
IPR002934. Nucleotidyltransferase.
[Graphical view]
PANTHERiPTHR11258. PTHR11258. 1 hit.
PfamiPF01909. NTP_transf_2. 1 hit.
PF10421. OAS1_C. 1 hit.
[Graphical view]
PROSITEiPS00832. 25A_SYNTH_1. 1 hit.
PS00833. 25A_SYNTH_2. 1 hit.
PS50152. 25A_SYNTH_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5B850-1 [UniParc]FASTAAdd to Basket

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MMDLRNTPAK SLDKFIEDYL LPDTCFRMQI NHAIDIICGF LKERCFRGSS    50
YPVCVSKVVK GGSSGKGTTL RGRSDADLVV FLSPLTTFQD QLNRRGEFIQ 100
EIRRQLEACQ REERAFSVKF EVQAPRRDNP RALSFVLSSL QLGEGVEFDV 150
LPAFDALGQL TGGYKPDPQI YVKLIEECTY LQKEGEFSTC FTELQRDFLK 200
ERPTKLKSLI RLVKHWYQNC KKKLGKLPPQ YALELLTVYA WERGSMKTHF 250
NTAQGFRTVL ELVINYQQLC IYWTKYYDFK NPIIEKYLSR QLEKPRPVIL 300
DPADPTGNLG GGDPKGWRQL AQEAEAWLNY PCFKNWDGSP VSSWILLVRP 350
PASSLPFIPA PLHEA 365
Length:365
Mass (Da):41,906
Last modified:September 23, 2008 - v1
Checksum:iB943690F270057BE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM163425 Genomic DNA. Translation: CAQ57746.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM163425 Genomic DNA. Translation: CAQ57746.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG000994.

Family and domain databases

Gene3Di 1.10.1410.20. 1 hit.
InterProi IPR006117. 2-5-oligoadenylate_synth_CS.
IPR006116. 2-5-oligoadenylate_synth_N.
IPR018952. 2-5-oligoAdlate_synth_1_dom2/C.
IPR026774. 2-5A_synthase.
IPR002934. Nucleotidyltransferase.
[Graphical view ]
PANTHERi PTHR11258. PTHR11258. 1 hit.
Pfami PF01909. NTP_transf_2. 1 hit.
PF10421. OAS1_C. 1 hit.
[Graphical view ]
PROSITEi PS00832. 25A_SYNTH_1. 1 hit.
PS00833. 25A_SYNTH_2. 1 hit.
PS50152. 25A_SYNTH_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Ferguson W.G.
    Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: LeeImported.
  2. "Long-Term Balancing Selection at the Antiviral Gene OAS1 in Central African Chimpanzees."
    Ferguson W., Dvora S., Fikes R.W., Stone A.C., Boissinot S.
    Mol. Biol. Evol. 29:1093-1103(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: LeeImported.

Entry informationi

Entry nameiB5B850_PANTR
AccessioniPrimary (citable) accession number: B5B850
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 6, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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