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B5B2U1

- B5B2U1_MOUSE

UniProt

B5B2U1 - B5B2U1_MOUSE

Protein
Submitted name:

Nuclear factor of activated T-cells c3 isoform IAL-Xa

Gene

Nfatc3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. chromatin binding Source: MGI
    2. DNA binding Source: MGI
    3. protein binding Source: MGI
    4. sequence-specific DNA binding transcription factor activity Source: MGI

    GO - Biological processi

    1. cellular respiration Source: MGI
    2. cellular response to calcium ion Source: MGI
    3. cellular response to lithium ion Source: MGI
    4. heart development Source: MGI
    5. muscle cell development Source: MGI
    6. patterning of blood vessels Source: MGI
    7. positive regulation of transcription from RNA polymerase II promoter Source: MGI
    8. regulation of transcription, DNA-templated Source: MGI
    9. smooth muscle cell differentiation Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Nuclear factor of activated T-cells c3 isoform IAL-XaImported
    Gene namesi
    Name:Nfatc3Imported
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:103296. Nfatc3.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: MGI
    2. cytosol Source: MGI
    3. nucleus Source: MGI

    Keywords - Cellular componenti

    NucleusUniRule annotation

    Expressioni

    Gene expression databases

    GenevestigatoriB5B2U1.

    Structurei

    3D structure databases

    ProteinModelPortaliB5B2U1.
    SMRiB5B2U1. Positions 412-693.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 RHD (Rel-like) domain.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG069754.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    2.60.40.340. 1 hit.
    InterProiIPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002909. IPT.
    IPR008366. NFAT.
    IPR008967. p53-like_TF_DNA-bd.
    IPR011539. RHD.
    [Graphical view]
    PANTHERiPTHR12533. PTHR12533. 1 hit.
    PfamiPF00554. RHD. 1 hit.
    [Graphical view]
    PRINTSiPR01789. NUCFACTORATC.
    SMARTiSM00429. IPT. 1 hit.
    [Graphical view]
    SUPFAMiSSF49417. SSF49417. 1 hit.
    SSF81296. SSF81296. 1 hit.
    PROSITEiPS50254. REL_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B5B2U1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQRPRRVLFS VSAQLPSRTR PGPSDLDLEP DDCASIYIFN VDPPPSTLNS     50
    SLGLPHHGLL QSHSSVLSPS FQLQGYKNYE GTGDISESKY SPLGGPKPFE 100
    CPSIQITSIS PNCHQGTDAH EDDLHINDPE REYLERPSRD HLYLPLEPSY 150
    RESSLSPSPA SSISSRSWFS DASSCESLSH IYDDVDSELN EAAARFTLGS 200
    PLTSPGGSPG GCPGEESWHQ QYGSGHSLSP RQSPCHSPRS SITDENWLSP 250
    RPASGPSSRP TSPCGKRRHS SAEVCYAGSL SPHHSPVPSP GHSPRGSVTE 300
    DTWLTAPVHT GSGLSPAPFP FQYCVETDIP LKTRKTSEDQ AAILPGKLEI 350
    CSDDQGNLSP SRETSVDDGL GSQYPLKKDS SGDQFLSVPS PFTWSKPKPG 400
    HTPIFRTSSL PPLDWPLPTH FGQCELKIEV QPKTHHRAHY ETEGSRGAVK 450
    ASTGGHPVVK LLGYSEKPIN LQMFIGTADD RYLRPHAFYQ VHRITGKTVA 500
    TASQEIIIAS TKVLEIPLLP ENNMSASIDC AGILKLRNSD IELRKGETDI 550
    GRKNTRVRLV FRVHIPQPSG KVLSLQIASI PVECSQRSAQ ELPHIEKYSI 600
    NSCSVNGGHE MIVTGSNFLP ESKIIFLEKG QDGRPHWEAE GKIIREKCQG 650
    AHIVLEVPPY HNPAVTSAVQ VHFYLCNGKR KKSQSQRFTY TPVLMKQEQR 700
    EDTDLPSVPS LPVPHSAQAQ RPSSETGHPH DRAMSAPGSL LCQVQPAYTS 750
    MVASTHLPQL QCRDEGAGKE QHIATSSVMH QPFQVTPTSP IGSSYQSIQT 800
    SMYNGPTCLP VNPASSQEFD PVLFQQDAAL SSLVNLGCQP LSPIPFHSSN 850
    SDATGHLLAH SPHSVQTPPH LQSMGYHCSN AGQTALSSPV ADQITGQPSS 900
    HLQPITYCPS HPGSATAASP AASHPLASSP ISGPSSPQLQ PMPYQSPSSG 950
    TASSPSPTTR MHSGQHSTQA QSTGQGGLSV PSSLVCHSLC DPASFPPGGA 1000
    TVSIKPEPED QEPNFATIGL QDITLDDDQF ISDLEHQPSG STEKWPNHSE 1050
    FSCPVPFWRI 1060
    Length:1,060
    Mass (Da):114,491
    Last modified:September 23, 2008 - v1
    Checksum:i358420E756821C8D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EU887626 mRNA. Translation: ACG55646.1.
    UniGeneiMm.383185.

    Genome annotation databases

    UCSCiuc009nfe.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EU887626 mRNA. Translation: ACG55646.1 .
    UniGenei Mm.383185.

    3D structure databases

    ProteinModelPortali B5B2U1.
    SMRi B5B2U1. Positions 412-693.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc009nfe.2. mouse.

    Organism-specific databases

    MGIi MGI:103296. Nfatc3.

    Phylogenomic databases

    HOVERGENi HBG069754.

    Miscellaneous databases

    NextBioi 35547138.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori B5B2U1.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    2.60.40.340. 1 hit.
    InterProi IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002909. IPT.
    IPR008366. NFAT.
    IPR008967. p53-like_TF_DNA-bd.
    IPR011539. RHD.
    [Graphical view ]
    PANTHERi PTHR12533. PTHR12533. 1 hit.
    Pfami PF00554. RHD. 1 hit.
    [Graphical view ]
    PRINTSi PR01789. NUCFACTORATC.
    SMARTi SM00429. IPT. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49417. SSF49417. 1 hit.
    SSF81296. SSF81296. 1 hit.
    PROSITEi PS50254. REL_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Alternative splicing and expression of human and mouse NFAT genes."
      Vihma H., Pruunsild P., Timmusk T.
      Genomics 0:0-0(2008)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6Imported.

    Entry informationi

    Entry nameiB5B2U1_MOUSE
    AccessioniPrimary (citable) accession number: B5B2U1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)