Nuclear factor of activated T-cells c3 isoform IB-deltaXa

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B5B2S1 (B5B2S1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 42. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Submitted name:
Nuclear factor of activated T-cells c3 isoform IB-deltaXa EMBL ACG55626.1

Submitted name:
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3, isoform CRA_b EMBL EAW83211.1

Gene names

Name:	NFATC3 EMBL ACG55626.1
ORF Names:	hCG_28103 EMBL EAW83211.1

Organism

Homo sapiens (Human) EMBL ACG55626.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1075 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 RHD (Rel-like) domain. RuleBase RU003997

Ontologies

Keywords
Cellular component	Nucleus RuleBase RU003998
Gene Ontology (GO)
Biological_process	cellular respiration Inferred from electronic annotation. Source: Compara cellular response to lithium ion Inferred from electronic annotation. Source: Compara heart development Inferred from electronic annotation. Source: Compara muscle cell development Inferred from electronic annotation. Source: Compara patterning of blood vessels Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara smooth muscle cell differentiation Inferred from electronic annotation. Source: Compara
Cellular_component	cytosol Inferred from electronic annotation. Source: Compara nucleolus Inferred from direct assay. Source: HPA plasma membrane Inferred from direct assay. Source: HPA
Molecular_function	DNA binding Inferred from electronic annotation. Source: Compara chromatin binding Inferred from electronic annotation. Source: Compara sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

B5B2S1 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 0B25D61A2B56D898
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FASTA

1,075

115,594

        10         20         30         40         50         60 
MTTANCGAHD ELDFKLVFGE DGAPAPPPPG SRPADLEPDD CASIYIFNVD PPPSTLTTPL 

        70         80         90        100        110        120 
CLPHHGLPSH SSVLSPSFQL QSHKNYEGTC EIPESKYSPL GGPKPFECPS IQITSISPNC 

       130        140        150        160        170        180 
HQELDAHEDD LQINDPEREF LERPSRDHLY LPLEPSYRES SLSPSPASSI SSRSWFSDAS 

       190        200        210        220        230        240 
SCESLSHIYD DVDSELNEAA ARFTLGSPLT SPGGSPGGCP GEETWHQQYG LGHSLSPRQS 

       250        260        270        280        290        300 
PCHSPRSSVT DENWLSPRPA SGPSSRPTSP CGKRRHSSAE VCYAGSLSPH HSPVPSPGHS 

       310        320        330        340        350        360 
PRGSVTEDTW LNASVHGGSG LGPAVFPFQY CVETDIPLKT RKTSEDQAAI LPGKLELCSD 

       370        380        390        400        410        420 
DQGSLSPARE TSIDDGLGSQ YPLKKDSCGD QFLSVPSPFT WSKPKPGHTP IFRTSSLPPL 

       430        440        450        460        470        480 
DWPLPAHFGQ CELKIEVQPK THHRAHYETE GSRGAVKAST GGHPVVKLLG YNEKPINLQM 

       490        500        510        520        530        540 
FIGTADDRYL RPHAFYQVHR ITGKTVATAS QEIIIASTKV LEIPLLPENN MSASIDCAGI 

       550        560        570        580        590        600 
LKLRNSDIEL RKGETDIGRK NTRVRLVFRV HIPQPSGKVL SLQIASIPVE CSQRSAQELP 

       610        620        630        640        650        660 
HIEKYSINSC SVNGGHEMVV TGSNFLPESK IIFLEKGQDG RPQWEVEGKI IREKCQGAHI 

       670        680        690        700        710        720 
VLEVPPYHNP AVTAAVQVHF YLCNGKRKKS QSQRFTYTPV LMKQEHREEI DLSSVPSLPV 

       730        740        750        760        770        780 
PHPAQTQRPS SDSGCSHDSV LSGQRSLICS IPQTYASMVT SSHLPQLQCR DESVSKEQHM 

       790        800        810        820        830        840 
IPSPIVHQPF QVTPTPPVGS SYQPMQTNVV YNGPTCLPIN AASSQEFDSV LFQQDATLSG 

       850        860        870        880        890        900 
LVNLGCQPLS SIPFHSSNSG STGHLLAHTP HSVHTLPHLQ SMGYHCSNTG QRSLSSPVAD 

       910        920        930        940        950        960 
QITGQPSSQL QPITYGPSHS GSATTASPAA SHPLASSPLS GPPSPQLQPM PYQSPSSGTA 

       970        980        990       1000       1010       1020 
SSPSPATRMH SGQHSTQAQS TGQGGLSAPS SLICHSLCDP ASFPPDGATV SIKPEPEDRE 

      1030       1040       1050       1060       1070 
PNFATIGLQD ITLDDVNEII GRDMSQISVS QGAGVSRQAP LPSPESLDLG RSDGL

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Cross-references

Sequence databases
EMBL GenBank DDBJ	EU887606 mRNA. Translation: ACG55626.1. CH471092 Genomic DNA. Translation: EAW83211.1.
IPI	IPI00030369.
RefSeq	NP_775188.1. NM_173165.2.
UniGene	Hs.436585.
3D structure databases
ProteinModelPortal	B5B2S1.
ModBase	Search...
Protein-protein interaction databases
STRING	B5B2S1.
Proteomic databases
PRIDE	B5B2S1.
Protocols and materials databases
DNASU	4775.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4775.
KEGG	hsa:4775.
Organism-specific databases
CTD	4775.
PharmGKB	PA247.
Phylogenomic databases
HOVERGEN	HBG069754.
KO	K04446.
OMA	ASSQEFD.
PhylomeDB	B5B2S1.
Gene expression databases
ArrayExpress	B5B2S1.
Bgee	B5B2S1.
Family and domain databases
Gene3D	2.60.40.10. 1 hit. 2.60.40.340. 1 hit.
InterPro	IPR013783. Ig-like_fold. IPR014756. Ig_E-set. IPR002909. IPT_TIG_rcpt. IPR008366. NFAT. IPR008967. p53-like_TF_DNA-bd. IPR011539. RHD. [Graphical view]
PANTHER	PTHR12533. PTHR12533. 1 hit.
Pfam	PF00554. RHD. 1 hit. [Graphical view]
PRINTS	PR01789. NUCFACTORATC.
SMART	SM00429. IPT. 1 hit. [Graphical view]
SUPFAM	SSF81296. Ig_E-set. 1 hit. SSF49417. P53_like_DNA_bnd. 1 hit.
PROSITE	PS50254. REL_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	NFATC3. human.
GenomeRNAi	4775.
NextBio	18410.

Entry information

Entry name

B5B2S1_HUMAN

Accession

Primary (citable) accession number: B5B2S1

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	May 1, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info

[1]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Alternative splicing and expression of human and mouse NFAT genes." Vihma H., Pruunsild P., Timmusk T. Genomics 0:0-0(2008) Cited for: NUCLEOTIDE SEQUENCE.

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Other

Entry information