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B5B2P4

- B5B2P4_HUMAN

UniProt

B5B2P4 - B5B2P4_HUMAN

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Protein
Submitted name: Nuclear factor of activated T-cells c2 isoform IA-IIS-deltaXa
Gene
NFATC2
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: Ensembl
  2. sequence-specific DNA binding transcription factor activity Source: Ensembl
  3. transcription regulatory region DNA binding Source: Ensembl

GO - Biological processi

  1. cytokine production Source: Ensembl
  2. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear factor of activated T-cells c2 isoform IA-IIS-deltaXaImported
Submitted name:
Nuclear factor of activated T-cells c2 isoform IB-IIS-deltaXaImported
Gene namesi
Name:NFATC2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. nucleus Source: UniProtKB-KW
  3. ribonucleoprotein complex Source: Ensembl
  4. transcription factor complex Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Expressioni

Gene expression databases

ArrayExpressiB5B2P4.
BgeeiB5B2P4.

Family & Domainsi

Sequence similaritiesi

Contains 1 RHD (Rel-like) domain.UniRule annotation

Phylogenomic databases

HOVERGENiHBG069754.
KOiK17332.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.340. 1 hit.
InterProiIPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
IPR008366. NFAT.
IPR008967. p53-like_TF_DNA-bd.
IPR011539. RHD.
[Graphical view]
PANTHERiPTHR12533. PTHR12533. 1 hit.
PfamiPF00554. RHD. 1 hit.
PF01833. TIG. 1 hit.
[Graphical view]
PRINTSiPR01789. NUCFACTORATC.
SMARTiSM00429. IPT. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiPS50254. REL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5B2P4-1 [UniParc]FASTAAdd to Basket

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MSPRTSLAED SCLGRHSPVP RPASRSSSPG AKRRHSCAEA LVALPPGASP    50
QRSRSPSPQP SSHVAPQDHG SPAGYPPVAG SAVIMDALNS LATDSPCGIP 100
PKMWKTSPDP SPVSAAPSKA GLPRHIYPAV EFLGPCEQGE RRNSAPESIL 150
LVPPTWPKPL VPAIPICSIP VTASLPPLEW PLSSQSGSYE LRIEVQPKPH 200
HRAHYETEGS RGAVKAPTGG HPVVQLHGYM ENKPLGLQIF IGTADERILK 250
PHAFYQVHRI TGKTVTTTSY EKIVGNTKVL EIPLEPKNNM RATIDCAGIL 300
KLRNADIELR KGETDIGRKN TRVRLVFRVH IPESSGRIVS LQTASNPIEC 350
SQRSAHELPM VERQDTDSCL VYGGQQMILT GQNFTSESKV VFTEKTTDGQ 400
QIWEMEATVD KDKSQPNMLF VEIPEYRNKH IRTPVKVNFY VINGKRKRSQ 450
PQHFTYHPVP AIKTEPTDEY DPTLICSPTH GGLGSQPYYP QHPMVAESPS 500
CLVATMAPCQ QFRTGLSSPD ARYQQQNPAA VLYQRSKSLS PSLLGYQQPA 550
LMAAPLSLAD AHRSVLVHAG SQGQSSALLH PSPTNQQASP VIHYSPTNQQ 600
LRCGSHQEFQ HIMYCENFAP GTTRPGPPPV SQGQRLSPGS YPTVIQQQNA 650
TSQRAAKNGP PVSDQKEVLP AGVTIKQEQN LDQTYLDDVN EIIRKEFSGP 700
PARNQT 706
Length:706
Mass (Da):77,061
Last modified:September 23, 2008 - v1
Checksum:i69EA7AAB0EC54634
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EU887579 mRNA. Translation: ACG55599.1.
EU887580 mRNA. Translation: ACG55600.1.
RefSeqiNP_001245224.1. NM_001258295.1.
NP_001245226.1. NM_001258297.1.
UniGeneiHs.744148.

Genome annotation databases

GeneIDi4773.
KEGGihsa:4773.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EU887579 mRNA. Translation: ACG55599.1 .
EU887580 mRNA. Translation: ACG55600.1 .
RefSeqi NP_001245224.1. NM_001258295.1.
NP_001245226.1. NM_001258297.1.
UniGenei Hs.744148.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 4773.
KEGGi hsa:4773.

Organism-specific databases

CTDi 4773.

Phylogenomic databases

HOVERGENi HBG069754.
KOi K17332.

Miscellaneous databases

GenomeRNAii 4773.
NextBioi 18400.

Gene expression databases

ArrayExpressi B5B2P4.
Bgeei B5B2P4.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
2.60.40.340. 1 hit.
InterProi IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
IPR008366. NFAT.
IPR008967. p53-like_TF_DNA-bd.
IPR011539. RHD.
[Graphical view ]
PANTHERi PTHR12533. PTHR12533. 1 hit.
Pfami PF00554. RHD. 1 hit.
PF01833. TIG. 1 hit.
[Graphical view ]
PRINTSi PR01789. NUCFACTORATC.
SMARTi SM00429. IPT. 1 hit.
[Graphical view ]
SUPFAMi SSF49417. SSF49417. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEi PS50254. REL_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Alternative splicing and expression of human and mouse NFAT genes."
    Vihma H., Pruunsild P., Timmusk T.
    Genomics 0:0-0(2008)
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiB5B2P4_HUMAN
AccessioniPrimary (citable) accession number: B5B2P4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 19, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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