B5B2P4 (B5B2P4_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Nuclear factor of activated T-cells c2 isoform IA-IIS-deltaXa EMBL ACG55599.1

Submitted name:
Nuclear factor of activated T-cells c2 isoform IB-IIS-deltaXa EMBL ACG55600.1

Gene names

Name:

NFATC2 EMBL ACG55599.1

Organism

Homo sapiens (Human) EMBL ACG55599.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	706 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 RHD (Rel-like) domain. RuleBase RU003997

Ontologies

Keywords
Cellular component	Nucleus RuleBase RU003998
Gene Ontology (GO)
Biological_process	cytokine production Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara
Cellular_component	cytosol Inferred from electronic annotation. Source: Compara ribonucleoprotein complex Inferred from electronic annotation. Source: Compara transcription factor complex Inferred from electronic annotation. Source: Compara
Molecular_function	sequence-specific DNA binding Inferred from electronic annotation. Source: Compara sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: Compara transcription regulatory region DNA binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B5B2P4 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 69EA7AAB0EC54634	FASTA	706	77,061
	10 20 30 40 50 60 MSPRTSLAED SCLGRHSPVP RPASRSSSPG AKRRHSCAEA LVALPPGASP QRSRSPSPQP 70 80 90 100 110 120 SSHVAPQDHG SPAGYPPVAG SAVIMDALNS LATDSPCGIP PKMWKTSPDP SPVSAAPSKA 130 140 150 160 170 180 GLPRHIYPAV EFLGPCEQGE RRNSAPESIL LVPPTWPKPL VPAIPICSIP VTASLPPLEW 190 200 210 220 230 240 PLSSQSGSYE LRIEVQPKPH HRAHYETEGS RGAVKAPTGG HPVVQLHGYM ENKPLGLQIF 250 260 270 280 290 300 IGTADERILK PHAFYQVHRI TGKTVTTTSY EKIVGNTKVL EIPLEPKNNM RATIDCAGIL 310 320 330 340 350 360 KLRNADIELR KGETDIGRKN TRVRLVFRVH IPESSGRIVS LQTASNPIEC SQRSAHELPM 370 380 390 400 410 420 VERQDTDSCL VYGGQQMILT GQNFTSESKV VFTEKTTDGQ QIWEMEATVD KDKSQPNMLF 430 440 450 460 470 480 VEIPEYRNKH IRTPVKVNFY VINGKRKRSQ PQHFTYHPVP AIKTEPTDEY DPTLICSPTH 490 500 510 520 530 540 GGLGSQPYYP QHPMVAESPS CLVATMAPCQ QFRTGLSSPD ARYQQQNPAA VLYQRSKSLS 550 560 570 580 590 600 PSLLGYQQPA LMAAPLSLAD AHRSVLVHAG SQGQSSALLH PSPTNQQASP VIHYSPTNQQ 610 620 630 640 650 660 LRCGSHQEFQ HIMYCENFAP GTTRPGPPPV SQGQRLSPGS YPTVIQQQNA TSQRAAKNGP 670 680 690 700 PVSDQKEVLP AGVTIKQEQN LDQTYLDDVN EIIRKEFSGP PARNQT

References

[1]	"Alternative splicing and expression of human and mouse NFAT genes." Vihma H., Pruunsild P., Timmusk T. Genomics 0:0-0(2008) Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EU887579 mRNA. Translation: ACG55599.1. EU887580 mRNA. Translation: ACG55600.1.
IPI	IPI00939862.
RefSeq	NP_001245224.1. NM_001258295.1. NP_001245226.1. NM_001258297.1.
UniGene	Hs.599855.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B5B2P4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4773.
KEGG	hsa:4773.
Organism-specific databases
CTD	4773.
Phylogenomic databases
HOVERGEN	HBG069754.
KO	K04446.
Gene expression databases
ArrayExpress	B5B2P4.
Bgee	B5B2P4.
Family and domain databases
Gene3D	2.60.40.10. 1 hit. 2.60.40.340. 1 hit.
InterPro	IPR013783. Ig-like_fold. IPR014756. Ig_E-set. IPR002909. IPT_TIG_rcpt. IPR008366. NFAT. IPR008967. p53-like_TF_DNA-bd. IPR011539. RHD. [Graphical view]
PANTHER	PTHR12533. PTHR12533. 1 hit.
Pfam	PF00554. RHD. 1 hit. PF01833. TIG. 1 hit. [Graphical view]
PRINTS	PR01789. NUCFACTORATC.
SMART	SM00429. IPT. 1 hit. [Graphical view]
SUPFAM	SSF81296. Ig_E-set. 1 hit. SSF49417. P53_like_DNA_bnd. 1 hit.
PROSITE	PS50254. REL_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	4773.
NextBio	18400.

Entry information

Entry name

B5B2P4_HUMAN

Accession

Primary (citable) accession number: B5B2P4

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	April 3, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.