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B5B2P0 (B5B2P0_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

Nuclear factor of activated T-cells c2 isoform IB-IIS-Xa EMBL ACG55596.1

Nuclear factor of-activated T-cells, cytoplasmic 2 Ensembl ENSP00000477342 Ensembl ENSP00000477142
Gene names
Name:NFATC2 Ensembl ENSP00000477342 EMBL ACG55595.1 Ensembl ENSP00000477142
OrganismHomo sapiens (Human) [Reference proteome] EMBL ACG55595.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length702 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 RHD (Rel-like) domain. RuleBase RU003997

Ontologies

Keywords
   Cellular componentNucleus RuleBase RU003998
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionsequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B5B2P0 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: D3CA427C994A5605

FASTA70276,700
        10         20         30         40         50         60 
MSPRTSLAED SCLGRHSPVP RPASRSSSPG AKRRHSCAEA LVALPPGASP QRSRSPSPQP 

        70         80         90        100        110        120 
SSHVAPQDHG SPAGYPPVAG SAVIMDALNS LATDSPCGIP PKMWKTSPDP SPVSAAPSKA 

       130        140        150        160        170        180 
GLPRHIYPAV EFLGPCEQGE RRNSAPESIL LVPPTWPKPL VPAIPICSIP VTASLPPLEW 

       190        200        210        220        230        240 
PLSSQSGSYE LRIEVQPKPH HRAHYETEGS RGAVKAPTGG HPVVQLHGYM ENKPLGLQIF 

       250        260        270        280        290        300 
IGTADERILK PHAFYQVHRI TGKTVTTTSY EKIVGNTKVL EIPLEPKNNM RATIDCAGIL 

       310        320        330        340        350        360 
KLRNADIELR KGETDIGRKN TRVRLVFRVH IPESSGRIVS LQTASNPIEC SQRSAHELPM 

       370        380        390        400        410        420 
VERQDTDSCL VYGGQQMILT GQNFTSESKV VFTEKTTDGQ QIWEMEATVD KDKSQPNMLF 

       430        440        450        460        470        480 
VEIPEYRNKH IRTPVKVNFY VINGKRKRSQ PQHFTYHPVP AIKTEPTDEY DPTLICSPTH 

       490        500        510        520        530        540 
GGLGSQPYYP QHPMVAESPS CLVATMAPCQ QFRTGLSSPD ARYQQQNPAA VLYQRSKSLS 

       550        560        570        580        590        600 
PSLLGYQQPA LMAAPLSLAD AHRSVLVHAG SQGQSSALLH PSPTNQQASP VIHYSPTNQQ 

       610        620        630        640        650        660 
LRCGSHQEFQ HIMYCENFAP GTTRPGPPPV SQGQRLSPGS YPTVIQQQNA TSQRAAKNGP 

       670        680        690        700 
PVSDQKEVLP AGVTIKQEQN LDQTYLDDEL IDTHLSWIQN IL 

« Hide

References

« Hide 'large scale' references
[1]"The DNA sequence and comparative analysis of human chromosome 20."
Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. expand/collapse author list , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"Alternative splicing and expression of human and mouse NFAT genes."
Vihma H., Pruunsild P., Timmusk T.
Genomics 0:0-0(2008)
Cited for: NUCLEOTIDE SEQUENCE.
[3]Ensembl
Submitted (DEC-2013) to UniProtKB
Cited for: IDENTIFICATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL035682 Genomic DNA. No translation available.
AL035684 Genomic DNA. No translation available.
AL132866 Genomic DNA. No translation available.
EU887575 mRNA. Translation: ACG55595.1.
EU887576 mRNA. Translation: ACG55596.1.
RefSeqNP_001245223.1. NM_001258294.1.
NP_001245225.1. NM_001258296.1.
NP_036472.2. NM_012340.4.
NP_775114.1. NM_173091.3.
UniGeneHs.744148.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000609507; ENSP00000477342; ENSG00000101096.
ENST00000610033; ENSP00000477142; ENSG00000101096.
GeneID4773.
KEGGhsa:4773.
UCSCuc010zyv.3. human.

Organism-specific databases

CTD4773.
HGNCHGNC:7776. NFATC2.
GenAtlasSearch...

Phylogenomic databases

HOVERGENHBG069754.
KOK17332.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
2.60.40.340. 1 hit.
InterProIPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
IPR008366. NFAT.
IPR008967. p53-like_TF_DNA-bd.
IPR011539. RHD.
[Graphical view]
PANTHERPTHR12533. PTHR12533. 1 hit.
PfamPF00554. RHD. 1 hit.
PF01833. TIG. 1 hit.
[Graphical view]
PRINTSPR01789. NUCFACTORATC.
SMARTSM00429. IPT. 1 hit.
[Graphical view]
SUPFAMSSF49417. SSF49417. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEPS50254. REL_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi4773.
NextBio18400.

Entry information

Entry nameB5B2P0_HUMAN
AccessionPrimary (citable) accession number: B5B2P0
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: April 16, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.