Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B5B2N2

- B5B2N2_MOUSE

UniProt

B5B2N2 - B5B2N2_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Nuclear factor of activated T-cells c1 isoform IA-IXL

Gene

Nfatc1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: MGI
  2. RNA polymerase II core promoter sequence-specific DNA binding Source: MGI
  3. sequence-specific DNA binding Source: MGI
  4. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. calcium ion transport Source: MGI
  2. epithelial to mesenchymal transition Source: MGI
  3. G1/S transition of mitotic cell cycle Source: MGI
  4. heart development Source: MGI
  5. intracellular signal transduction Source: MGI
  6. osteoclast differentiation Source: MGI
  7. positive regulation of gene expression Source: MGI
  8. positive regulation of transcription, DNA-templated Source: MGI
  9. positive regulation of transcription from RNA polymerase II promoter Source: MGI
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_188202. FCERI mediated Ca+2 mobilization.
REACT_221970. Ca2+ pathway.

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear factor of activated T-cells c1 isoform IA-IXLImported
Submitted name:
Nuclear factor of-activated T-cells, cytoplasmic 1Imported
Gene namesi
Name:Nfatc1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 18

Organism-specific databases

MGIiMGI:102469. Nfatc1.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. nuclear chromatin Source: Ensembl
  3. nucleus Source: MGI
  4. transcription factor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Expressioni

Gene expression databases

GenevestigatoriB5B2N2.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000077196.

Family & Domainsi

Sequence similaritiesi

Contains 1 RHD (Rel-like) domain.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00550000074562.
HOGENOMiHOG000231780.
HOVERGENiHBG069754.
KOiK04446.
OMAiHNNNQFF.
OrthoDBiEOG79PJND.
TreeFamiTF326480.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.340. 1 hit.
InterProiIPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
IPR008366. NFAT.
IPR015647. NFAT1.
IPR008967. p53-like_TF_DNA-bd.
IPR011539. RHD.
[Graphical view]
PANTHERiPTHR12533. PTHR12533. 1 hit.
PTHR12533:SF5. PTHR12533:SF5. 1 hit.
PfamiPF00554. RHD. 1 hit.
PF01833. TIG. 1 hit.
[Graphical view]
PRINTSiPR01789. NUCFACTORATC.
SMARTiSM00429. IPT. 1 hit.
[Graphical view]
SUPFAMiSSF49417. SSF49417. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEiPS50254. REL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5B2N2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPSTSFPVPS KFPLGPPAAV CGSGETLRPA PPSGGTMKAA EEEHYSYVSP
60 70 80 90 100
SVTSTLPLPT AHSALPAACH DLQTSTPGIS AVPSANHPPS YGGAVDSGPS
110 120 130 140 150
GYFLSSGNTR PNGAPTLESP RIEITSYLGL HHGSGQFFHD VEVEDVLPSC
160 170 180 190 200
KRSPSTATLH LPSLEAYRDP SCLSPASSLS SRSCNSEASS YESNYSYPYA
210 220 230 240 250
SPQTSPWQSP CVSPKTTDPE EGFPRSLGAC HLLGSPRHSP STSPRASITE
260 270 280 290 300
ESWLGARGSR PTSPCNKRKY SLNGRQPSCS PHHSPTPSPH GSPRVSVTED
310 320 330 340 350
TWLGNTTQYT SSAIVAAINA LTTDSTLDLG DGVPIKSRKT ALEHAPSVAL
360 370 380 390 400
KVEPAGEDLG TTPPTSDFPP EEYTFQHLRK GAFCEQYLSV PQASYQWAKP
410 420 430 440 450
KSLSPTSYMS PSLPALDWQL PSHSGPYELR IEVQPKSHHR AHYETEGSRG
460 470 480 490 500
AVKASAGGHP IVQLHGYLEN EPLTLQLFIG TADDRLLRPH AFYQVHRITG
510 520 530 540 550
KTVSTTSHEI ILSNTKVLEI PLLPENNMRA IIDCAGILKL RNSDIELRKG
560 570 580 590 600
ETDIGRKNTR VRLVFRVHIP QPNGRTLSLQ VASNPIECSQ RSAQELPLVE
610 620 630 640 650
KQSTDSYPVI GGKKMVLSGH NFLQDSKVIF VEKAPDGHHV WEMEAKTDRD
660 670 680 690 700
LCKPNSLVVE IPPFRNQRIT SPVQVSFYVC NGKRKRSQYQ RFTYLPANVP
710 720 730 740 750
IIKTEPTDDF EPALTCGPMS QGISPLPRPY YSQQLTMPPD PGSCLVAGFA
760 770 780 790 800
PCSQRNTLMP TPPNASPKLH DLSSPAYTKG LTNPGHSGHL GLQPPASEAP
810 820 830 840 850
TMQEVPRPMA IQPNSPEQPP SARLQPQVSP HLNSSCPLGR RQVLCPNSPS
860 870 880 890 900
SPLPSAAQEP ACLQSSALPP DMGHRQPQPQ KVQRNESPAV LPEVCEDSGH
910 920 930
NLAPIPVVIK QEPEELDQLY LDDVNEIIRN DLSSTIPHS
Length:939
Mass (Da):101,610
Last modified:September 23, 2008 - v1
Checksum:iA7639723937E81F7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123818 Genomic DNA. No translation available.
AC149054 Genomic DNA. No translation available.
EU887567 mRNA. Translation: ACG55587.1.
RefSeqiNP_001157582.1. NM_001164110.1.
UniGeneiMm.329560.

Genome annotation databases

EnsembliENSMUST00000170905; ENSMUSP00000129001; ENSMUSG00000033016.
GeneIDi18018.
KEGGimmu:18018.
UCSCiuc012bfm.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123818 Genomic DNA. No translation available.
AC149054 Genomic DNA. No translation available.
EU887567 mRNA. Translation: ACG55587.1 .
RefSeqi NP_001157582.1. NM_001164110.1.
UniGenei Mm.329560.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000077196.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000170905 ; ENSMUSP00000129001 ; ENSMUSG00000033016 .
GeneIDi 18018.
KEGGi mmu:18018.
UCSCi uc012bfm.1. mouse.

Organism-specific databases

CTDi 4772.
MGIi MGI:102469. Nfatc1.

Phylogenomic databases

GeneTreei ENSGT00550000074562.
HOGENOMi HOG000231780.
HOVERGENi HBG069754.
KOi K04446.
OMAi HNNNQFF.
OrthoDBi EOG79PJND.
TreeFami TF326480.

Enzyme and pathway databases

Reactomei REACT_188202. FCERI mediated Ca+2 mobilization.
REACT_221970. Ca2+ pathway.

Miscellaneous databases

NextBioi 293057.
SOURCEi Search...

Gene expression databases

Genevestigatori B5B2N2.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
2.60.40.340. 1 hit.
InterProi IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002909. IPT.
IPR008366. NFAT.
IPR015647. NFAT1.
IPR008967. p53-like_TF_DNA-bd.
IPR011539. RHD.
[Graphical view ]
PANTHERi PTHR12533. PTHR12533. 1 hit.
PTHR12533:SF5. PTHR12533:SF5. 1 hit.
Pfami PF00554. RHD. 1 hit.
PF01833. TIG. 1 hit.
[Graphical view ]
PRINTSi PR01789. NUCFACTORATC.
SMARTi SM00429. IPT. 1 hit.
[Graphical view ]
SUPFAMi SSF49417. SSF49417. 1 hit.
SSF81296. SSF81296. 1 hit.
PROSITEi PS50254. REL_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Alternative splicing and expression of human and mouse NFAT genes."
    Vihma H., Pruunsild P., Timmusk T.
    Genomics 92:279-291(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB5B2N2_MOUSE
AccessioniPrimary (citable) accession number: B5B2N2
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3