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B5AK60 (B5AK60_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length1216 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the ABC transporter superfamily. RuleBase RU000684

Contains ABC transmembrane type-1 domains. SAAS SAAS011527

Contains ABC transmembrane type-domains. SAAS SAAS011527

Sequences

Sequence LengthMass (Da)Tools
B5AK60 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 227233F5F2259A8C

FASTA1,216134,032
        10         20         30         40         50         60 
MDLEGDRNGG AKKKNFFKLN NKSEKDKKEK KPTVSVFSMF RYSNWLDKLY MVVGTLAAII 

        70         80         90        100        110        120 
HGAGLPLMML VFGEMTDIFA NAGNLEDLMS NITNRSDIND TGFFMNLEED MTSDVSKINE 

       130        140        150        160        170        180 
GIGDKIGMFF QSMATFFTGF IVGFTRGWKL TLVILAISPV LGLSAAVWAK ILSSFTDKEL 

       190        200        210        220        230        240 
LAYAKAGAVA EEVLAAIRTV IAFGGQKKEL ERYNKNLEEA KRIGIKKAIT ANISIGAAFL 

       250        260        270        280        290        300 
LIYASYALAF WYGTTLVLSG EYSIGQVLTV FFSVLIGAFS VGQASPSIEA FANARGAAYE 

       310        320        330        340        350        360 
IFKIIDNKPS IDSYSKSGHK PDNIKGNLEF RNVHFSYPSR KEVKILKGLN LKVQSGQTVA 

       370        380        390        400        410        420 
LVGNSGCGKS TTVQLMQRLY DPTEGMVSVD GQDIRTINVR FLREIIGVVS QEPVLFATTI 

       430        440        450        460        470        480 
AENIRYGREN VTMDEIEKAV KEANAYDFIM KLPHKFDTLV GERGAQLSGG QKQRIAIARA 

       490        500        510        520        530        540 
LVRNPKILLL DEATSALDTE SEAVVQVALD KARKGRTTIV IAHRLSTVRN ADVIAGFDDG 

       550        560        570        580        590        600 
VIVEKGNHDE LMKEKGIYFK LVTMQTAGNE VELENAADES KSEIDALEMS SNDSRSSLIR 

       610        620        630        640        650        660 
KRSTRRSVRG SQAQDRKLST KEALDESIPP VSFWRIMKLN LTEWPYFVVG VFCAIINGGL 

       670        680        690        700        710        720 
QPAFAIIFSK IIGVFTRIDD PETKRQNSNL FSLLFLALGI ISFITFFLQG FTFGKAGEIL 

       730        740        750        760        770        780 
TKRLRYMVFR SMLRQDVSWF DDPKNTTGAL TTRLANDAAQ VKGAIGSRLA VITQNIANLG 

       790        800        810        820        830        840 
TGIIISFIYG WQLTLLLLAI VPIIAIAGVV EMKMLSGQAL KDKKELEGSG KIATEAIENF 

       850        860        870        880        890        900 
RTVVSLTQEQ KFEHMYAQSL QVPYRNSLRK AHIFGITFSF TQAMMYFSYA GCFRFGAYLV 

       910        920        930        940        950        960 
AHKLMSFEDV LLVFSAVVFG AMAVGQVSSF APDYAKAKIS AAHIIMIIEK TPLIDSYSTE 

       970        980        990       1000       1010       1020 
GLMPNTLEGN VTFGEVVFNY PTRPDIPVLQ GLSLEVKKGQ TLALVGSSGC GKSTVVQLLE 

      1030       1040       1050       1060       1070       1080 
RFYDPLAGKV LLDGKEIKRL NVQWLRAHLG IVSQEPILFD CSIAENIAYG DNSRVVSQEE 

      1090       1100       1110       1120       1130       1140 
IVRAAKEANI HAFIESLPNK YSTKVGDKGT QLSGGQKQRI AIARALVRQP HILLLDEATS 

      1150       1160       1170       1180       1190       1200 
ALDTESEKVV QEALDKAREG RTCIVIAHRL STIQNADLIV VFQNGRVKEH GTHQQLLAQK 

      1210 
GIYFSMVSVQ AGTKRQ 

« Hide

References

« Hide 'large scale' references
[1]"The DNA sequence of human chromosome 7."
Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L. expand/collapse author list , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"A quantitative atlas of mitotic phosphorylation."
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[3]"Cloning of P-glycoprotein cDNA sequence from breast cancer MCF7 cell line."
Jiang Y., Sun Q., Xie Z., Liu F., Xu W., Wang Y.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[4]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[5]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC002457 Genomic DNA. No translation available.
AC005068 Genomic DNA. No translation available.
EU854148 mRNA. Translation: ACF94688.1.
UniGeneHs.489033.
Hs.737655.

3D structure databases

ProteinModelPortalB5AK60.
SMRB5AK60. Positions 32-566.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000543898; ENSP00000444095; ENSG00000085563.
UCSCuc011khc.2. human.

Organism-specific databases

HGNCHGNC:40. ABCB1.
GenAtlasSearch...

Phylogenomic databases

HOVERGENHBG080809.

Family and domain databases

Gene3D3.40.50.300. 2 hits.
InterProIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR001140. ABC_transptr_TM_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio35477809.

Entry information

Entry nameB5AK60_HUMAN
AccessionPrimary (citable) accession number: B5AK60
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 9, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.