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Protein
Submitted name:

Advanced glycosylation end product-specific receptor

Gene

RAGE

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Advanced glycosylation end product-specific receptorImported
Submitted name:
Advanced glycosylation end products transcript variantImported
Submitted name:
Soluble RAGE variant 5Imported
Gene namesi
Name:RAGEImported
Synonyms:AGERImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

HGNCiHGNC:320. AGER.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000204305.
ENSG00000206320.
ENSG00000229058.
ENSG00000234729.
ENSG00000237405.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500764283224 – 128Sequence analysisAdd BLAST105

Proteomic databases

PeptideAtlasiB5A982.
PRIDEiB5A982.

Expressioni

Gene expression databases

BgeeiENSG00000204305.
ExpressionAtlasiB5A982. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000364217.

Structurei

3D structure databases

ProteinModelPortaliB5A982.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 116Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST86

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IVT2. Eukaryota.
ENOG4111C4I. LUCA.
GeneTreeiENSGT00530000063457.
HOVERGENiHBG084276.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
[Graphical view]
PfamiPF13895. Ig_2. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5A982-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAGTAVGAW VLVLSLWGAV VGAQNITARI GEPLVLKCKG APKKPPQRLE
60 70 80 90 100
WKLNTGRTEA WKVLSPQGGG PWDSVARVLP NGSLFLPAVG IQDEGIFRCQ
110 120
AMNRNGKETK SNYRVRVYQF ENLHNYSL
Length:128
Mass (Da):14,017
Last modified:September 23, 2008 - v1
Checksum:i687A511FB6879DE8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662830 Genomic DNA. No translation available.
AL662884 Genomic DNA. No translation available.
AL845464 Genomic DNA. No translation available.
BX284686 Genomic DNA. No translation available.
BX927239 Genomic DNA. No translation available.
EU826620 mRNA. Translation: ACF47656.1.
FJ545655 mRNA. Translation: ACL80027.1.
UniGeneiHs.534342.

Genome annotation databases

EnsembliENST00000538695; ENSP00000445389; ENSG00000204305.
ENST00000548959; ENSP00000447095; ENSG00000234729.
ENST00000550854; ENSP00000450205; ENSG00000206320.
ENST00000551684; ENSP00000448028; ENSG00000237405.
ENST00000553014; ENSP00000446582; ENSG00000229058.
UCSCiuc063nqa.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662830 Genomic DNA. No translation available.
AL662884 Genomic DNA. No translation available.
AL845464 Genomic DNA. No translation available.
BX284686 Genomic DNA. No translation available.
BX927239 Genomic DNA. No translation available.
EU826620 mRNA. Translation: ACF47656.1.
FJ545655 mRNA. Translation: ACL80027.1.
UniGeneiHs.534342.

3D structure databases

ProteinModelPortaliB5A982.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000364217.

Proteomic databases

PeptideAtlasiB5A982.
PRIDEiB5A982.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000538695; ENSP00000445389; ENSG00000204305.
ENST00000548959; ENSP00000447095; ENSG00000234729.
ENST00000550854; ENSP00000450205; ENSG00000206320.
ENST00000551684; ENSP00000448028; ENSG00000237405.
ENST00000553014; ENSP00000446582; ENSG00000229058.
UCSCiuc063nqa.1. human.

Organism-specific databases

HGNCiHGNC:320. AGER.
OpenTargetsiENSG00000204305.
ENSG00000206320.
ENSG00000229058.
ENSG00000234729.
ENSG00000237405.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IVT2. Eukaryota.
ENOG4111C4I. LUCA.
GeneTreeiENSGT00530000063457.
HOVERGENiHBG084276.

Miscellaneous databases

ChiTaRSiAGER. human.

Gene expression databases

BgeeiENSG00000204305.
ExpressionAtlasiB5A982. baseline and differential.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
[Graphical view]
PfamiPF13895. Ig_2. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB5A982_HUMAN
AccessioniPrimary (citable) accession number: B5A982
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 2, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.