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Protein
Submitted name:

Soluble TNFR1B variant 1

Gene

TNFRSF1B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Soluble TNFR1B variant 1Imported
Submitted name:
Tumor necrosis factor receptor superfamily member 1BImported
Gene namesi
Name:TNFRSF1BImported
Synonyms:TNFR1BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000028137.16
HGNCiHGNC:11917 TNFRSF1B

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000028137

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501456771323 – 155Sequence analysisAdd BLAST133

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi54 ↔ 67PROSITE-ProRule annotation
Disulfide bondi57 ↔ 75PROSITE-ProRule annotation
Disulfide bondi78 ↔ 93PROSITE-ProRule annotation
Disulfide bondi100 ↔ 118PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSG00000028137

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 75TNFR-CysInterPro annotationAdd BLAST37
Repeati39 – 75TNFR-CysPROSITE-ProRule annotationAdd BLAST37
Domaini77 – 118TNFR-CysInterPro annotationAdd BLAST42
Repeati77 – 118TNFR-CysPROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IJ06 Eukaryota
ENOG410YPQW LUCA
GeneTreeiENSGT00760000119204
HOGENOMiHOG000132845

Family and domain databases

InterProiView protein in InterPro
IPR001368 TNFR/NGFR_Cys_rich_reg
PfamiView protein in Pfam
PF00020 TNFR_c6, 2 hits
SMARTiView protein in SMART
SM00208 TNFR, 3 hits
PROSITEiView protein in PROSITE
PS00652 TNFR_NGFR_1, 2 hits
PS50050 TNFR_NGFR_2, 2 hits

Sequencei

Sequence statusi: Complete.

B5A977-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPVAVWAAL AVGLELWAAA HALPAQVAFT PYAPEPGSTC RLREYYDQTA
60 70 80 90 100
QMCCSKCSPG QHAKVFCTKT SDTVCDSCED STYTQLWNWV PECLSCGSRC
110 120 130 140 150
SSDQVETQAC TREQNRICTC RPGWYCALSK QEGCRLCAPL RKCRPGFGVA

RPDLS
Length:155
Mass (Da):17,015
Last modified:September 23, 2008 - v1
Checksum:i3C1B33890D3E340E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL031276 Genomic DNA No translation available.
AL357835 Genomic DNA No translation available.
EU826615 mRNA Translation: ACF47651.1
UniGeneiHs.256278

Genome annotation databases

EnsembliENST00000536782; ENSP00000440425; ENSG00000028137
UCSCiuc057cji.1 human

Similar proteinsi

Entry informationi

Entry nameiB5A977_HUMAN
AccessioniPrimary (citable) accession number: B5A977
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: May 23, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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