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Protein
Submitted name:

Soluble TNFR1B variant 1

Gene

TNFR1B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Soluble TNFR1B variant 1Imported
Submitted name:
Tumor necrosis factor receptor superfamily member 1BImported
Gene namesi
Name:TNFR1BImported
Synonyms:TNFRSF1BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:11917. TNFRSF1B.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000028137.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500968558323 – 155Sequence analysisAdd BLAST133

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi54 ↔ 67PROSITE-ProRule annotation
Disulfide bondi57 ↔ 75PROSITE-ProRule annotation
Disulfide bondi78 ↔ 93PROSITE-ProRule annotation
Disulfide bondi100 ↔ 118PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSG00000028137.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000365435.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 75TNFR-CysInterPro annotationAdd BLAST37
Repeati39 – 75TNFR-CysPROSITE-ProRule annotationAdd BLAST37
Domaini77 – 118TNFR-CysInterPro annotationAdd BLAST42
Repeati77 – 118TNFR-CysPROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IJ06. Eukaryota.
ENOG410YPQW. LUCA.
GeneTreeiENSGT00760000119204.
HOGENOMiHOG000132845.

Family and domain databases

InterProiView protein in InterPro
IPR001368. TNFR/NGFR_Cys_rich_reg.
PfamiView protein in Pfam
PF00020. TNFR_c6. 2 hits.
SMARTiView protein in SMART
SM00208. TNFR. 3 hits.
PROSITEiView protein in PROSITE
PS00652. TNFR_NGFR_1. 2 hits.
PS50050. TNFR_NGFR_2. 2 hits.

Sequencei

Sequence statusi: Complete.

B5A977-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPVAVWAAL AVGLELWAAA HALPAQVAFT PYAPEPGSTC RLREYYDQTA
60 70 80 90 100
QMCCSKCSPG QHAKVFCTKT SDTVCDSCED STYTQLWNWV PECLSCGSRC
110 120 130 140 150
SSDQVETQAC TREQNRICTC RPGWYCALSK QEGCRLCAPL RKCRPGFGVA

RPDLS
Length:155
Mass (Da):17,015
Last modified:September 23, 2008 - v1
Checksum:i3C1B33890D3E340E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL031276 Genomic DNA. No translation available.
AL357835 Genomic DNA. No translation available.
EU826615 mRNA. Translation: ACF47651.1.
UniGeneiHs.256278.

Genome annotation databases

EnsembliENST00000536782; ENSP00000440425; ENSG00000028137.
UCSCiuc057cji.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL031276 Genomic DNA. No translation available.
AL357835 Genomic DNA. No translation available.
EU826615 mRNA. Translation: ACF47651.1.
UniGeneiHs.256278.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000365435.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000536782; ENSP00000440425; ENSG00000028137.
UCSCiuc057cji.1. human.

Organism-specific databases

HGNCiHGNC:11917. TNFRSF1B.
OpenTargetsiENSG00000028137.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IJ06. Eukaryota.
ENOG410YPQW. LUCA.
GeneTreeiENSGT00760000119204.
HOGENOMiHOG000132845.

Miscellaneous databases

ChiTaRSiTNFRSF1B. human.

Gene expression databases

BgeeiENSG00000028137.

Family and domain databases

InterProiView protein in InterPro
IPR001368. TNFR/NGFR_Cys_rich_reg.
PfamiView protein in Pfam
PF00020. TNFR_c6. 2 hits.
SMARTiView protein in SMART
SM00208. TNFR. 3 hits.
PROSITEiView protein in PROSITE
PS00652. TNFR_NGFR_1. 2 hits.
PS50050. TNFR_NGFR_2. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiB5A977_HUMAN
AccessioniPrimary (citable) accession number: B5A977
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 15, 2017
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.