B5A8L9 (B5A8L9_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Myocyte enhancer factor 2cb EMBL ACF49365.1

Gene names

Name:

mef2cb EMBL ACF49365.1 ZFIN ZDB-GENE-040901-7

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL ACF49365.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	475 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Nucleus By similarity RuleBase RU000476.
Sequence similarities	Contains 1 MADS-box domain. RuleBase RU000476 SAAS SAAS002100

Ontologies

Keywords
Biological process	Transcription Transcription regulation RuleBase RU000476 SAAS SAAS002100
Cellular component	Nucleus SAAS SAAS002100 RuleBase RU000476
Ligand	DNA-binding RuleBase RU000476 SAAS SAAS002100
Gene Ontology (GO)
Biological process	embryonic heart tube morphogenesis Inferred from mutant phenotype. Source: ZFIN regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW protein dimerization activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B5A8L9 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 584C2B2B55D76816	FASTA	475	51,364
	10 20 30 40 50 60 MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS TNKLFQYAST 70 80 90 100 110 120 DMDKVLLKYT EYNEPHESRT NSDIVETLRK KGLNGCDSPD PDADDSVGHS PESKDKYREI 130 140 150 160 170 180 NDDIDLHMIS RQRICAVPSS TYDMTIPVNN QIYPGNHNLL PLAHHGLQRN SMSPGVTHRP 190 200 210 220 230 240 PSAGGLMGTD LSTGAGTSAG KDGIPTYYRN GYGNHRNSPG LLVSSGGMNK SMQAKSPPPV 250 260 270 280 290 300 NLGMNSRKPD LRVLIPPGAK NNMPSINQRI NNSQSAQSLA TPVVSVATPT LPGQGMGGYP 310 320 330 340 350 360 SAISTSYGTE YSLSSADLSS ISGFNSANTL HLGSMSGWQQ HQIQNMQHSA LSQLGNCSSS 370 380 390 400 410 420 HLCQGSNLSL PSTQSLHIKS EPVSPPRDRS SSTTPGGYGQ LPSHQQHQGP TSQGRQDSGR 430 440 450 460 470 SPADSLSSCG SSHEGSDRDE HRPDFHSPLG LGRPGLDDQD SPSIKRVRLS EGWAT

References

[1]	"mef2ca is required in cranial neural crest to effect Endothelin1 signaling in zebrafish." Miller C.T., Swartz M.E., Khuu P.A., Walker M.B., Eberhart J.K., Kimmel C.B. Dev. Biol. 308:144-157(2007) [PubMed: 17574232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Miller C.T., Swartz M.E., Khuu P.A., Chen V.P., Walker M.B., Eberhart J.K., Kimmel C.B. Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EU825718 mRNA. Translation: ACF49365.1.
IPI	IPI00863039.
RefSeq	NP_001124434.1. NM_001130962.1.
UniGene	Dr.99428.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B5A8L9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	798771.
KEGG	dre:798771.
Organism-specific databases
CTD	798771.
ZFIN	ZDB-GENE-040901-7. mef2cb.
Phylogenomic databases
GeneTree	ENSGT00390000011828.
HOGENOM	HBG443633.
HOVERGEN	HBG053944.
OrthoDB	EOG4DFPNH.
Gene expression databases
Bgee	B5A8L9.
Family and domain databases
InterPro	IPR002100. TF_MADSbox. [Graphical view]
KO	K04454.
Pfam	PF00319. SRF-TF. 1 hit. [Graphical view]
PRINTS	PR00404. MADSDOMAIN.
SMART	SM00432. MADS. 1 hit. [Graphical view]
SUPFAM	SSF55455. TF_MADSbox. 1 hit.
PROSITE	PS00350. MADS_BOX_1. 1 hit. PS50066. MADS_BOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B5A8L9_DANRE

Accession

Primary (citable) accession number: B5A8L9

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)