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B5A250

- B5A250_HUMAN

UniProt

B5A250 - B5A250_HUMAN

Protein
Submitted name:

CREBBP

Gene

CREBBP

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. antigen binding Source: Ensembl
    2. chromatin DNA binding Source: Ensembl
    3. histone acetyltransferase activity Source: Ensembl
    4. lysine N-acetyltransferase activity, acting on acetyl phosphate as donor Source: Ensembl
    5. RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: Ensembl

    GO - Biological processi

    1. cellular response to hydrogen peroxide Source: Ensembl
    2. cellular response to organic cyclic compound Source: Ensembl
    3. digestive tract development Source: Ensembl
    4. germ-line stem cell maintenance Source: Ensembl
    5. heart development Source: Ensembl
    6. liver development Source: Ensembl
    7. lung development Source: Ensembl
    8. negative regulation of cellular metabolic process Source: Ensembl
    9. organ morphogenesis Source: Ensembl
    10. positive regulation of axon extension Source: Ensembl
    11. positive regulation of cell death Source: Ensembl
    12. positive regulation of cell size Source: Ensembl
    13. positive regulation of collagen biosynthetic process Source: Ensembl
    14. positive regulation of DNA binding Source: Ensembl
    15. positive regulation of glycoprotein biosynthetic process Source: Ensembl
    16. positive regulation of protein binding Source: Ensembl
    17. positive regulation of protein import into nucleus, translocation Source: Ensembl
    18. positive regulation of protein phosphorylation Source: Ensembl
    19. positive regulation of protein secretion Source: Ensembl
    20. positive regulation of proteolysis Source: Ensembl
    21. positive regulation of sarcomere organization Source: Ensembl
    22. positive regulation of sequence-specific DNA binding transcription factor activity Source: Ensembl
    23. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    24. positive regulation of translation Source: Ensembl
    25. protein-DNA complex assembly Source: Ensembl
    26. protein kinase B signaling Source: Ensembl
    27. regulation of angiotensin metabolic process Source: Ensembl
    28. response to calcium ion Source: Ensembl
    29. response to cobalt ion Source: Ensembl
    30. response to drug Source: Ensembl
    31. response to estrogen Source: Ensembl
    32. response to ethanol Source: Ensembl
    33. response to fatty acid Source: Ensembl
    34. response to glucocorticoid Source: Ensembl
    35. response to glucose Source: Ensembl
    36. response to hypoxia Source: Ensembl
    37. response to retinoic acid Source: Ensembl
    38. response to tumor necrosis factor Source: Ensembl
    39. skeletal muscle tissue development Source: Ensembl
    40. somitogenesis Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    CREBBPImported
    Gene namesi
    Name:CREBBPImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. chromatin Source: Ensembl
    2. condensed chromosome outer kinetochore Source: Ensembl
    3. cytoplasm Source: Ensembl
    4. histone acetyltransferase complex Source: Ensembl
    5. transcription factor complex Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiB5A250.

    Expressioni

    Gene expression databases

    ArrayExpressiB5A250.
    BgeeiB5A250.

    Family & Domainsi

    Family and domain databases

    Gene3Di1.20.920.10. 1 hit.
    InterProiIPR001487. Bromodomain.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    B5A250-1 [UniParc]FASTAAdd to Basket

    « Hide

    QALMPTLEAL YRQDPESLPF RQPVDPQLLG IP                      32
    Length:32
    Mass (Da):3,634
    Last modified:September 23, 2008 - v1
    Checksum:i14DA9622ABA86171
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei32 – 321Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EU790779 Genomic DNA. Translation: ACF57273.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EU790779 Genomic DNA. Translation: ACF57273.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi B5A250.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    ChiTaRSi CREBBP. human.
    NextBioi 35477740.

    Gene expression databases

    ArrayExpressi B5A250.
    Bgeei B5A250.

    Family and domain databases

    Gene3Di 1.20.920.10. 1 hit.
    InterProi IPR001487. Bromodomain.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Spectrum of CREBBP mutations in Indian patients with Rubinstein-Taybi syndrome."
      Sharma N., Mali A.M., Bapat S.A.
      J. Biosci. 35:187-202(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiB5A250_HUMAN
    AccessioniPrimary (citable) accession number: B5A250
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.