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B5A250

- B5A250_HUMAN

UniProt

B5A250 - B5A250_HUMAN

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Protein
Submitted name: CREBBP
Gene
CREBBP
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 5 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: Ensembl
  2. antigen binding Source: Ensembl
  3. chromatin DNA binding Source: Ensembl
  4. histone acetyltransferase activity Source: Ensembl
  5. lysine N-acetyltransferase activity Source: Ensembl

GO - Biological processi

  1. cellular response to hydrogen peroxide Source: Ensembl
  2. cellular response to organic cyclic compound Source: Ensembl
  3. digestive tract development Source: Ensembl
  4. germ-line stem cell maintenance Source: Ensembl
  5. heart development Source: Ensembl
  6. liver development Source: Ensembl
  7. lung development Source: Ensembl
  8. negative regulation of cellular metabolic process Source: Ensembl
  9. organ morphogenesis Source: Ensembl
  10. positive regulation of DNA binding Source: Ensembl
  11. positive regulation of axon extension Source: Ensembl
  12. positive regulation of cell death Source: Ensembl
  13. positive regulation of cell size Source: Ensembl
  14. positive regulation of collagen biosynthetic process Source: Ensembl
  15. positive regulation of glycoprotein biosynthetic process Source: Ensembl
  16. positive regulation of protein binding Source: Ensembl
  17. positive regulation of protein import into nucleus, translocation Source: Ensembl
  18. positive regulation of protein phosphorylation Source: Ensembl
  19. positive regulation of protein secretion Source: Ensembl
  20. positive regulation of proteolysis Source: Ensembl
  21. positive regulation of sarcomere organization Source: Ensembl
  22. positive regulation of sequence-specific DNA binding transcription factor activity Source: Ensembl
  23. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  24. positive regulation of translation Source: Ensembl
  25. protein kinase B signaling Source: Ensembl
  26. protein-DNA complex assembly Source: Ensembl
  27. regulation of angiotensin metabolic process Source: Ensembl
  28. response to calcium ion Source: Ensembl
  29. response to cobalt ion Source: Ensembl
  30. response to drug Source: Ensembl
  31. response to estrogen Source: Ensembl
  32. response to ethanol Source: Ensembl
  33. response to fatty acid Source: Ensembl
  34. response to glucocorticoid Source: Ensembl
  35. response to glucose Source: Ensembl
  36. response to hypoxia Source: Ensembl
  37. response to retinoic acid Source: Ensembl
  38. response to tumor necrosis factor Source: Ensembl
  39. skeletal muscle tissue development Source: Ensembl
  40. somitogenesis Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
CREBBPImported
Gene namesi
Name:CREBBPImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. chromatin Source: Ensembl
  2. condensed chromosome outer kinetochore Source: Ensembl
  3. cytoplasm Source: Ensembl
  4. histone acetyltransferase complex Source: Ensembl
  5. transcription factor complex Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB5A250.

Expressioni

Gene expression databases

ArrayExpressiB5A250.
BgeeiB5A250.

Family & Domainsi

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
InterProiIPR001487. Bromodomain.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B5A250-1 [UniParc]FASTAAdd to Basket

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QALMPTLEAL YRQDPESLPF RQPVDPQLLG IP                      32
Length:32
Mass (Da):3,634
Last modified:September 23, 2008 - v1
Checksum:i14DA9622ABA86171
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei32 – 321Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EU790779 Genomic DNA. Translation: ACF57273.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EU790779 Genomic DNA. Translation: ACF57273.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B5A250.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

ChiTaRSi CREBBP. human.
NextBioi 35477740.

Gene expression databases

ArrayExpressi B5A250.
Bgeei B5A250.

Family and domain databases

Gene3Di 1.20.920.10. 1 hit.
InterProi IPR001487. Bromodomain.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Spectrum of CREBBP mutations in Indian patients with Rubinstein-Taybi syndrome."
    Sharma N., Mali A.M., Bapat S.A.
    J. Biosci. 35:187-202(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiB5A250_HUMAN
AccessioniPrimary (citable) accession number: B5A250
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 9, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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