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- B5A250_HUMAN


B5A250 - B5A250_HUMAN

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Submitted name:




Homo sapiens (Human)
Unreviewed - Annotation score: 5 out of 5- Protein predictedi


GO - Molecular functioni

  1. antigen binding Source: Ensembl
  2. chromatin DNA binding Source: Ensembl
  3. histone acetyltransferase activity Source: Ensembl
  4. lysine N-acetyltransferase activity, acting on acetyl phosphate as donor Source: Ensembl
  5. pre-mRNA intronic binding Source: Ensembl
  6. RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: Ensembl
  7. RNA polymerase II core promoter sequence-specific DNA binding Source: Ensembl
  8. sequence-specific DNA binding transcription factor activity Source: Ensembl

GO - Biological processi

  1. cellular response to cAMP Source: Ensembl
  2. cellular response to dexamethasone stimulus Source: Ensembl
  3. cellular response to drug Source: Ensembl
  4. cellular response to glucose stimulus Source: Ensembl
  5. cellular response to hydrogen peroxide Source: Ensembl
  6. cellular response to mineralocorticoid stimulus Source: Ensembl
  7. cellular response to nerve growth factor stimulus Source: Ensembl
  8. cellular response to retinoic acid Source: Ensembl
  9. cellular response to trichostatin A Source: Ensembl
  10. circadian rhythm Source: Ensembl
  11. digestive tract development Source: Ensembl
  12. germ-line stem cell maintenance Source: Ensembl
  13. heart development Source: Ensembl
  14. histone H3 acetylation Source: Ensembl
  15. liver development Source: Ensembl
  16. lung development Source: Ensembl
  17. negative regulation of cell death Source: Ensembl
  18. negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Source: Ensembl
  19. negative regulation of miRNA metabolic process Source: Ensembl
  20. organ morphogenesis Source: Ensembl
  21. positive regulation of axon extension Source: Ensembl
  22. positive regulation of cell death Source: Ensembl
  23. positive regulation of cell size Source: Ensembl
  24. positive regulation of collagen biosynthetic process Source: Ensembl
  25. positive regulation of DNA binding Source: Ensembl
  26. positive regulation of glycoprotein biosynthetic process Source: Ensembl
  27. positive regulation of muscle atrophy Source: Ensembl
  28. positive regulation of protein acetylation Source: Ensembl
  29. positive regulation of protein binding Source: Ensembl
  30. positive regulation of protein import into nucleus, translocation Source: Ensembl
  31. positive regulation of protein phosphorylation Source: Ensembl
  32. positive regulation of protein secretion Source: Ensembl
  33. positive regulation of proteolysis Source: Ensembl
  34. positive regulation of sarcomere organization Source: Ensembl
  35. positive regulation of sequence-specific DNA binding transcription factor activity Source: Ensembl
  36. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  37. positive regulation of translation Source: Ensembl
  38. protein-DNA complex assembly Source: Ensembl
  39. protein kinase B signaling Source: Ensembl
  40. regulation of angiotensin metabolic process Source: Ensembl
  41. response to calcium ion Source: Ensembl
  42. response to cobalt ion Source: Ensembl
  43. response to estrogen Source: Ensembl
  44. response to ethanol Source: Ensembl
  45. response to fatty acid Source: Ensembl
  46. response to hypoxia Source: Ensembl
  47. response to tumor necrosis factor Source: Ensembl
  48. skeletal muscle tissue development Source: Ensembl
  49. somitogenesis Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Gene namesi
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. chromatin Source: Ensembl
  2. condensed chromosome outer kinetochore Source: Ensembl
  3. cytoplasm Source: Ensembl
  4. histone acetyltransferase complex Source: Ensembl
  5. protein-DNA complex Source: Ensembl
  6. transcription factor complex Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases



Gene expression databases

ExpressionAtlasiB5A250. baseline and differential.

Family & Domainsi

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
InterProiIPR001487. Bromodomain.
[Graphical view]


Sequence statusi: Fragment.

B5A250-1 [UniParc]FASTAAdd to Basket

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        10         20         30 
Mass (Da):3,634
Last modified:September 23, 2008 - v1

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei32 – 321Imported

Sequence databases

Select the link destinations:
Links Updated
EU790779 Genomic DNA. Translation: ACF57273.1.


Sequence databases

Select the link destinations:
Links Updated
EU790779 Genomic DNA. Translation: ACF57273.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B5A250.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

ChiTaRSi CREBBP. human.
NextBioi 35477740.

Gene expression databases

Bgeei B5A250.
ExpressionAtlasi B5A250. baseline and differential.

Family and domain databases

Gene3Di 1.20.920.10. 1 hit.
InterProi IPR001487. Bromodomain.
[Graphical view ]
ProtoNeti Search...


  1. "Spectrum of CREBBP mutations in Indian patients with Rubinstein-Taybi syndrome."
    Sharma N., Mali A.M., Bapat S.A.
    J. Biosci. 35:187-202(2010) [PubMed] [Europe PMC] [Abstract]

Entry informationi

Entry nameiB5A250_HUMAN
AccessioniPrimary (citable) accession number: B5A250
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 26, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.