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Protein
Submitted name:

CREBBP

Gene

CREBBP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. chromatin DNA binding Source: Ensembl
  2. histone acetyltransferase activity Source: Ensembl
  3. pre-mRNA intronic binding Source: Ensembl
  4. RNA polymerase II core promoter sequence-specific DNA binding Source: Ensembl

GO - Biological processi

  1. circadian rhythm Source: Ensembl
  2. germ-line stem cell maintenance Source: Ensembl
  3. heart development Source: Ensembl
  4. lung development Source: Ensembl
  5. organ morphogenesis Source: Ensembl
  6. positive regulation of protein binding Source: Ensembl
  7. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  8. skeletal muscle tissue development Source: Ensembl
  9. somitogenesis Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
CREBBPImported
Gene namesi
Name:CREBBPImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. condensed chromosome outer kinetochore Source: Ensembl
  2. histone acetyltransferase complex Source: Ensembl
  3. transcription factor complex Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB5A250.

Expressioni

Gene expression databases

BgeeiB5A250.
ExpressionAtlasiB5A250. baseline and differential.

Family & Domainsi

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
InterProiIPR001487. Bromodomain.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B5A250-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30 
QALMPTLEAL YRQDPESLPF RQPVDPQLLG IP
Length:32
Mass (Da):3,634
Last modified:September 22, 2008 - v1
Checksum:i14DA9622ABA86171
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei32 – 321Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU790779 Genomic DNA. Translation: ACF57273.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU790779 Genomic DNA. Translation: ACF57273.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB5A250.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

ChiTaRSiCREBBP. human.
NextBioi35477740.

Gene expression databases

BgeeiB5A250.
ExpressionAtlasiB5A250. baseline and differential.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
InterProiIPR001487. Bromodomain.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Spectrum of CREBBP mutations in Indian patients with Rubinstein-Taybi syndrome."
    Sharma N., Mali A.M., Bapat S.A.
    J. Biosci. 35:187-202(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiB5A250_HUMAN
AccessioniPrimary (citable) accession number: B5A250
Entry historyi
Integrated into UniProtKB/TrEMBL: September 22, 2008
Last sequence update: September 22, 2008
Last modified: March 3, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.