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B4YUQ9

- B4YUQ9_PONAB

UniProt

B4YUQ9 - B4YUQ9_PONAB

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Protein
Submitted name: Prostate-specific transglutaminase 4
Gene
TGM4
Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

Cofactori

Binds 1 calcium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei268 – 2681 By similarityUniRule annotation
Active sitei327 – 3271 By similarityUniRule annotation
Active sitei350 – 3501 By similarityUniRule annotation
Metal bindingi390 – 3901Calcium By similarity
Metal bindingi392 – 3921Calcium By similarity
Metal bindingi442 – 4421Calcium By similarity
Metal bindingi447 – 4471Calcium By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseImported, Transferase

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Prostate-specific transglutaminase 4Imported (EC:2.3.2.13Imported)
Gene namesi
Name:TGM4Imported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG004342.
KOiK05621.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 1 hit.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4YUQ9-1 [UniParc]FASTAAdd to Basket

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MMDTSKELQV LHVDFLKQEN AVSHHTWEFQ TSSPVFRRGQ VFHLRLVLNQ    50
PLQSYHQLKL EFSTGPNPSL AKHTLVVLDP RTPSDHYNWQ ATLQNESGKE 100
VTVAVTSTPN AILGEYQLNV KTGNHILKSE ENILYLLFNP WCKEDMVFMP 150
DEDERKEYIL NDTGCHYVGA ARSIKYKPWN FGQFEKNVLD CCISLLTESS 200
LKPTDRRDPV LVCRAMCAMM SFEKGQGVLI GNWTGDYEGG TAPYKWTGSA 250
PILQQYYNTK QAVXFGQCWV FAGILTTVLR ALGIPARSVT AFDSAHDTER 300
NLTVDTYVNE NGEKITNMTH DSVWNFHVWT DAWMKRPDLP KGYDGWQAVD 350
ATPQERSQGV FCCGPSPLTA IRKGDIFIVY DTRFVFSEVN GDRLIWLVKM 400
VNGQEELHII SMETTSIGKN ISTKAVGQDR RRDITYEYKY SEGSSEERQV 450
MDHAFLLLSS EREHRRPVKE NFLHMSVQSD DVLLGNPVNF TVILKRKTAA 500
LQNVNISGSF ELQLYTGKKV AKLCDLNKTS QIQGQVSEVT LTLDSKTYIN 550
SLAILDDEPV IRGFIIAEIV ESNEIMASEV FXSFQYPEFS IELPNTGRIG 600
QLLVCNCIFK NTLAIPLTDV KFSLESLGIS SLQTSDHGTV QPGETIQSQI 650
KCTPIKTGPK KFIVKLSSKQ VKEINAQKIV LITK 684
Length:684
Mass (Da):77,266
Last modified:September 23, 2008 - v1
Checksum:i6B897B0EEB17AB82
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EU685250 Genomic DNA. Translation: ACF75756.1.
RefSeqiNP_001128592.1. NM_001135120.1.
UniGeneiPab.19887.

Genome annotation databases

GeneIDi100189556.
KEGGipon:100189556.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EU685250 Genomic DNA. Translation: ACF75756.1 .
RefSeqi NP_001128592.1. NM_001135120.1.
UniGenei Pab.19887.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 100189556.
KEGGi pon:100189556.

Organism-specific databases

CTDi 7047.

Phylogenomic databases

HOVERGENi HBG004342.
KOi K05621.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 1 hit.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Hominoid seminal protein evolution and ancestral mating behavior."
    Carnahan S.J., Jensen-Seaman M.I.
    Am. J. Primatol. 70:939-948(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiB4YUQ9_PONAB
AccessioniPrimary (citable) accession number: B4YUQ9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 9, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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