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B4YUQ9

- B4YUQ9_PONAB

UniProt

B4YUQ9 - B4YUQ9_PONAB

Protein
Submitted name:

Prostate-specific transglutaminase 4

Gene

TGM4

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 calcium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei268 – 2681UniRule annotation
    Active sitei327 – 3271UniRule annotation
    Active sitei350 – 3501UniRule annotation
    Metal bindingi390 – 3901CalciumUniRule annotation
    Metal bindingi392 – 3921CalciumUniRule annotation
    Metal bindingi442 – 4421CalciumUniRule annotation
    Metal bindingi447 – 4471CalciumUniRule annotation

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein-glutamine gamma-glutamyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. peptide cross-linking Source: InterPro

    Keywords - Molecular functioni

    AcyltransferaseImported, Transferase

    Keywords - Ligandi

    CalciumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Prostate-specific transglutaminase 4Imported (EC:2.3.2.13Imported)
    Gene namesi
    Name:TGM4Imported
    OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
    Taxonomic identifieri9601 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG004342.
    KOiK05621.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view]
    PANTHERiPTHR11590. PTHR11590. 1 hit.
    PfamiPF00927. Transglut_C. 1 hit.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
    SMARTiSM00460. TGc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4YUQ9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMDTSKELQV LHVDFLKQEN AVSHHTWEFQ TSSPVFRRGQ VFHLRLVLNQ    50
    PLQSYHQLKL EFSTGPNPSL AKHTLVVLDP RTPSDHYNWQ ATLQNESGKE 100
    VTVAVTSTPN AILGEYQLNV KTGNHILKSE ENILYLLFNP WCKEDMVFMP 150
    DEDERKEYIL NDTGCHYVGA ARSIKYKPWN FGQFEKNVLD CCISLLTESS 200
    LKPTDRRDPV LVCRAMCAMM SFEKGQGVLI GNWTGDYEGG TAPYKWTGSA 250
    PILQQYYNTK QAVXFGQCWV FAGILTTVLR ALGIPARSVT AFDSAHDTER 300
    NLTVDTYVNE NGEKITNMTH DSVWNFHVWT DAWMKRPDLP KGYDGWQAVD 350
    ATPQERSQGV FCCGPSPLTA IRKGDIFIVY DTRFVFSEVN GDRLIWLVKM 400
    VNGQEELHII SMETTSIGKN ISTKAVGQDR RRDITYEYKY SEGSSEERQV 450
    MDHAFLLLSS EREHRRPVKE NFLHMSVQSD DVLLGNPVNF TVILKRKTAA 500
    LQNVNISGSF ELQLYTGKKV AKLCDLNKTS QIQGQVSEVT LTLDSKTYIN 550
    SLAILDDEPV IRGFIIAEIV ESNEIMASEV FXSFQYPEFS IELPNTGRIG 600
    QLLVCNCIFK NTLAIPLTDV KFSLESLGIS SLQTSDHGTV QPGETIQSQI 650
    KCTPIKTGPK KFIVKLSSKQ VKEINAQKIV LITK 684
    Length:684
    Mass (Da):77,266
    Last modified:September 23, 2008 - v1
    Checksum:i6B897B0EEB17AB82
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EU685250 Genomic DNA. Translation: ACF75756.1.
    RefSeqiNP_001128592.1. NM_001135120.1.
    UniGeneiPab.19887.

    Genome annotation databases

    GeneIDi100189556.
    KEGGipon:100189556.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EU685250 Genomic DNA. Translation: ACF75756.1 .
    RefSeqi NP_001128592.1. NM_001135120.1.
    UniGenei Pab.19887.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 100189556.
    KEGGi pon:100189556.

    Organism-specific databases

    CTDi 7047.

    Phylogenomic databases

    HOVERGENi HBG004342.
    KOi K05621.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view ]
    PANTHERi PTHR11590. PTHR11590. 1 hit.
    Pfami PF00927. Transglut_C. 1 hit.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
    SMARTi SM00460. TGc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Hominoid seminal protein evolution and ancestral mating behavior."
      Carnahan S.J., Jensen-Seaman M.I.
      Am. J. Primatol. 70:939-948(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiB4YUQ9_PONAB
    AccessioniPrimary (citable) accession number: B4YUQ9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)