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Protein
Submitted name:

Hexokinase 1

Gene

Hk1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • fructokinase activity Source: GO_Central
  • glucokinase activity Source: MGI
  • hexokinase activity Source: MGI
  • mannokinase activity Source: GO_Central

GO - Biological processi

  • canonical glycolysis Source: MGI
  • carbohydrate phosphorylation Source: GOC
  • cellular glucose homeostasis Source: GO_Central
  • glucose 6-phosphate metabolic process Source: GOC
  • glycolytic process Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase 1Imported
Submitted name:
Hexokinase-1Imported
Gene namesi
Name:Hk1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:96103. Hk1.

Subcellular locationi

GO - Cellular componenti

  • cilium Source: MGI
  • cytosol Source: MGI
  • membrane raft Source: MGI
  • mitochondrion Source: MGI
  • sperm principal piece Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiB4YB29. baseline and differential.
GenevestigatoriB4YB29.

Structurei

3D structure databases

ProteinModelPortaliB4YB29.
SMRiB4YB29. Positions 24-49.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000017159.
KOiK00844.

Sequencei

Sequence statusi: Fragment.

B4YB29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
MGQNCQRGQA VDVEPKIRPP LTEEKIDKYL YAMRLSDEIL IDILTRFKK
Length:49
Mass (Da):5,765
Last modified:September 23, 2008 - v1
Checksum:iD091CD6A97CC52F1
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei49 – 491Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126428 Genomic DNA. No translation available.
AC145297 Genomic DNA. No translation available.
EU430521 mRNA. Translation: ACF25876.1.
EU430522 mRNA. Translation: ACF25877.1.
EU430523 mRNA. Translation: ACF25878.1.
EU430524 mRNA. Translation: ACF25879.1.
EU430525 mRNA. Translation: ACF25880.1.
EU430526 mRNA. Translation: ACF25881.1.
EU430527 mRNA. Translation: ACF25882.1.
EU430528 mRNA. Translation: ACF25883.1.
EU430529 mRNA. Translation: ACF25884.1.
EU430530 mRNA. Translation: ACF25885.1.
EU430531 mRNA. Translation: ACF25886.1.
EU430532 mRNA. Translation: ACF25887.1.
EU430533 mRNA. Translation: ACF25888.1.
RefSeqiNP_034568.2. NM_010438.3.
UniGeneiMm.196605.

Genome annotation databases

EnsembliENSMUST00000130091; ENSMUSP00000122791; ENSMUSG00000037012.
ENSMUST00000132926; ENSMUSP00000115218; ENSMUSG00000037012.
ENSMUST00000133429; ENSMUSP00000123375; ENSMUSG00000037012.
ENSMUST00000134447; ENSMUSP00000122717; ENSMUSG00000037012.
ENSMUST00000134877; ENSMUSP00000121487; ENSMUSG00000037012.
ENSMUST00000135317; ENSMUSP00000115426; ENSMUSG00000037012.
ENSMUST00000136548; ENSMUSP00000122479; ENSMUSG00000037012.
ENSMUST00000140383; ENSMUSP00000114586; ENSMUSG00000037012.
ENSMUST00000143236; ENSMUSP00000115990; ENSMUSG00000037012.
ENSMUST00000154489; ENSMUSP00000118576; ENSMUSG00000037012.
GeneIDi15275.
KEGGimmu:15275.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126428 Genomic DNA. No translation available.
AC145297 Genomic DNA. No translation available.
EU430521 mRNA. Translation: ACF25876.1.
EU430522 mRNA. Translation: ACF25877.1.
EU430523 mRNA. Translation: ACF25878.1.
EU430524 mRNA. Translation: ACF25879.1.
EU430525 mRNA. Translation: ACF25880.1.
EU430526 mRNA. Translation: ACF25881.1.
EU430527 mRNA. Translation: ACF25882.1.
EU430528 mRNA. Translation: ACF25883.1.
EU430529 mRNA. Translation: ACF25884.1.
EU430530 mRNA. Translation: ACF25885.1.
EU430531 mRNA. Translation: ACF25886.1.
EU430532 mRNA. Translation: ACF25887.1.
EU430533 mRNA. Translation: ACF25888.1.
RefSeqiNP_034568.2. NM_010438.3.
UniGeneiMm.196605.

3D structure databases

ProteinModelPortaliB4YB29.
SMRiB4YB29. Positions 24-49.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000130091; ENSMUSP00000122791; ENSMUSG00000037012.
ENSMUST00000132926; ENSMUSP00000115218; ENSMUSG00000037012.
ENSMUST00000133429; ENSMUSP00000123375; ENSMUSG00000037012.
ENSMUST00000134447; ENSMUSP00000122717; ENSMUSG00000037012.
ENSMUST00000134877; ENSMUSP00000121487; ENSMUSG00000037012.
ENSMUST00000135317; ENSMUSP00000115426; ENSMUSG00000037012.
ENSMUST00000136548; ENSMUSP00000122479; ENSMUSG00000037012.
ENSMUST00000140383; ENSMUSP00000114586; ENSMUSG00000037012.
ENSMUST00000143236; ENSMUSP00000115990; ENSMUSG00000037012.
ENSMUST00000154489; ENSMUSP00000118576; ENSMUSG00000037012.
GeneIDi15275.
KEGGimmu:15275.

Organism-specific databases

CTDi3098.
MGIiMGI:96103. Hk1.

Phylogenomic databases

GeneTreeiENSGT00390000017159.
KOiK00844.

Miscellaneous databases

NextBioi287905.
SOURCEiSearch...

Gene expression databases

ExpressionAtlasiB4YB29. baseline and differential.
GenevestigatoriB4YB29.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Evidence for a possible involvement of hexokinase 1 in the pathology of hereditary motor and sensory neuropathy-Russe."
    Hantke J., Chandler D., Kalaydjieva L.
    Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.
    Tissue: BrainImported and TestisImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. "A tissue-specific atlas of mouse protein phosphorylation and expression."
    Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.
    Cell 143:1174-1189(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB4YB29_MOUSE
AccessioniPrimary (citable) accession number: B4YB29
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: May 27, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.