B4XN80 (B4XN80_9BURK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosyl-ATP pyrophosphatase HAMAP MF_01020
Short name=PRA-PH HAMAP MF_01020
EC=3.6.1.31 HAMAP MF_01020

Gene names

Name:

hisE HAMAP MF_01020 EMBL ABW35474.1

Organism

Burkholderia multivorans EMBL ABW35474.1

Taxonomic identifier

87883 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	121 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(5-phosphoribosyl)-ATP + H2O = 1-(5-phosphoribosyl)-AMP + diphosphate. SAAS SAAS008179 HAMAP MF_01020
Pathway	Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9. SAAS SAAS008179 HAMAP MF_01020
Subcellular location	Cytoplasm By similarity HAMAP MF_01020.
Sequence similarities	Belongs to the PRA-PH family. HAMAP MF_01020

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Histidine biosynthesis SAAS SAAS008179 HAMAP MF_01020
Cellular component	Cytoplasm HAMAP MF_01020
Ligand	ATP-binding SAAS SAAS008179 HAMAP MF_01020 Nucleotide-binding
Molecular function	Hydrolase SAAS SAAS008179 HAMAP MF_01020 EMBL ABW35474.1
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosyl-ATP diphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4XN80 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: F353E3D8A4266BD6	FASTA	121	13,216
	10 20 30 40 50 60 MTQSTEDTLL RLAGVIDSRK GGDPEQSYVS RLFHKGDDAV LKKIGEEATE VVLAAKDVRQ 70 80 90 100 110 120 GGAPSALVGE VADLWFHCLV MLSHFDLSPA DVIAELERRE GLSGIEEKAL RKRREREANG G

References

[1]

"Structural, evolutionary and genetic analysis of the histidine biosynthetic "core" in the genus Burkholderia." Papaleo M.C., Russo E., Fondi M., Emiliani G., Frandi A., Brilli M., Pastorelli R., Fani R. Gene 448:16-28(2009) [PubMed: 19683039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: FCF7 EMBL ABW35789.1, LMG13010 EMBL ABW35474.1, LMG17588 EMBL ABW35501.1 and LMG18822 EMBL ABW35510.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EU057648 Genomic DNA. Translation: ABW35474.1. EU057651 Genomic DNA. Translation: ABW35501.1. EU057652 Genomic DNA. Translation: ABW35510.1. EU057686 Genomic DNA. Translation: ABW35789.1.
3D structure databases
ProteinModelPortal	B4XN80.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
HAMAP	MF_01020. HisE. [Tree]
InterPro	IPR008179. PRib-ATP_PPHydrolase. IPR021130. PRib-ATP_PPHydrolase-like. [Graphical view]
Pfam	PF01503. PRA-PH. 1 hit. [Graphical view]
TIGRFAMs	TIGR03188. Histidine_hisI. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B4XN80_9BURK

Accession

Primary (citable) accession number: B4XN80

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	October 19, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)