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Protein
Submitted name:

Interferon gamma receptor 1

Gene
N/A
Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon gamma receptor 1Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi78 ↔ 86Combined sources
Disulfide bondi189 ↔ 194Combined sources
Disulfide bondi208 ↔ 229Combined sources

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000031140.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4EQ2X-ray2.50A25-237[»]
4EQ3X-ray2.00A25-237[»]
ProteinModelPortaliB4XN22.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG45077.
KOiK05132.
PhylomeDBiB4XN22.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR003961. FN3_dom.
IPR013783. Ig-like_fold.
IPR021126. Interferon_gamma_pox/mammal.
IPR008355. Interferon_gamma_rcpt_asu.
[Graphical view]
PANTHERiPTHR20859:SF5. PTHR20859:SF5. 1 hit.
PfamiPF07140. IFNGR1. 1 hit.
PF01108. Tissue_fac. 1 hit.
[Graphical view]
PRINTSiPR01777. INTERFERONGR.
SUPFAMiSSF49265. SSF49265. 2 hits.

Sequencei

Sequence statusi: Complete.

B4XN22-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAPLALMVL TALVAPGQNA ASLQERLPAV PSPTGTSVKS KNFRTVLYWQ
60 70 80 90 100
YPSMSETPHF VVEVKPYLSG KYQTVSTCVN ISATSCDLSE EINEIFHSYW
110 120 130 140 150
FRIKAIVGSQ QSQYVETDEF VLQKHGKIGP PKLNLSRHGA EIIVDVYHPE
160 170 180 190 200
FPSVEVRPWM REIYSELSYS VIFRNSENES RKNFTVADCE MNECNLSIPV
210 220 230 240 250
PSEGSTYCVS AKGHFFDDLI VGASSEESCI WVPITQAWST QVTIAVSSIV
260 270 280 290 300
LVVSLILTVC YGCKKLRKKN IKLPKSLVSV IRSLNADNSF ESRSEAKGIC
310 320 330 340 350
AASVMPVPSV SVPLTVNDDE ALLNVESAED VSPEDFSEGT SSGPPLEASH
360 370 380 390 400
KLEETSVQEN TEVPSDVEQS HKEKESDFIS DSSQTDVCSN SSGPVVSATE
410 420 430 440
IRQAVIPSSC PKFSGYDKPH VPLDVLIDVG EEQPVIAYRS TE
Length:442
Mass (Da):48,415
Last modified:September 23, 2008 - v1
Checksum:i3FF2ABBCF4602494
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU057149 mRNA. Translation: ABW37752.1.
RefSeqiNP_001123859.1. NM_001130387.1.
UniGeneiGga.47585.

Genome annotation databases

GeneIDi421685.
KEGGigga:421685.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU057149 mRNA. Translation: ABW37752.1.
RefSeqiNP_001123859.1. NM_001130387.1.
UniGeneiGga.47585.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4EQ2X-ray2.50A25-237[»]
4EQ3X-ray2.00A25-237[»]
ProteinModelPortaliB4XN22.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000031140.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi421685.
KEGGigga:421685.

Organism-specific databases

CTDi3459.

Phylogenomic databases

eggNOGiNOG45077.
KOiK05132.
PhylomeDBiB4XN22.

Miscellaneous databases

NextBioi20824418.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR003961. FN3_dom.
IPR013783. Ig-like_fold.
IPR021126. Interferon_gamma_pox/mammal.
IPR008355. Interferon_gamma_rcpt_asu.
[Graphical view]
PANTHERiPTHR20859:SF5. PTHR20859:SF5. 1 hit.
PfamiPF07140. IFNGR1. 1 hit.
PF01108. Tissue_fac. 1 hit.
[Graphical view]
PRINTSiPR01777. INTERFERONGR.
SUPFAMiSSF49265. SSF49265. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. "Molecular cloning and characterization of chicken interferon-gamma receptor alpha-chain."
    Han X., Chen T., Wang M.
    J. Interferon Cytokine Res. 28:445-454(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Crystal structure of the interferon gamma receptor alpha chain from chicken reveals an undetected extra helix compared with the human counterparts."
    Ping Z., Qi J., Sun Y., Lu G., Shi Y., Wang X., Gao G.F., Wang M.
    J. Interferon Cytokine Res. 34:41-51(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 25-237, DISULFIDE BONDS.

Entry informationi

Entry nameiB4XN22_CHICK
AccessioniPrimary (citable) accession number: B4XN22
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 22, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.