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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Anaeromyxobacter sp. (strain K)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. 6-phosphofructokinase (AnaeK_1792)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei389UniRule annotation1
Active sitei509UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciASP447217:G1GCK-3214-MONOMER
UniPathwayiUPA00109; UER00181
UPA00138

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:AnaeK_3178
OrganismiAnaeromyxobacter sp. (strain K)
Taxonomic identifieri447217 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeAnaeromyxobacteraceaeAnaeromyxobacter
Proteomesi
  • UP000001871 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001256901 – 546Glucose-6-phosphate isomeraseAdd BLAST546

Proteomic databases

PRIDEiB4ULW4

Structurei

3D structure databases

ProteinModelPortaliB4ULW4
SMRiB4ULW4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000261370
KOiK01810
OMAiTNSQHAF
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.101 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

B4ULW4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPDRTGPLLR TPAWRALEAH LAELQPLHLR ELFARDPGRG ERLVADGAGL
60 70 80 90 100
HLDYSKQRVT EETVRLLAAL AEARGLPERR AAMFRGEKVN VTEGRAVLHV
110 120 130 140 150
ALRAPRGERI LVDGSDVVPE VHAVLDRMAA FADQVRSGAW TGFTGKRIRT
160 170 180 190 200
VVNVGIGGSD LGPAMAYRAL RAYATRDLAF RFVSNVDGTD LAEAVRDLDP
210 220 230 240 250
AETLFLVASK TFTTLETMTN AASARSWLLA ALGDPRAVAR HFVAISTNEA
260 270 280 290 300
EVRRFGIDPA NMFGFWDWVG GRYSMDSAIG LSTMIAVGPE GFRELLAGFR
310 320 330 340 350
EMDEHFRDAP LERNLPALIG LLGVWNANLL GAETVAVLPY DQYLDRFPAY
360 370 380 390 400
LQQLTMESNG KRVTASGAPV EGHGTGAIYW GEPGTNGQHS FYQLLHQGTH
410 420 430 440 450
LVACDFIGFC RPLHALARHH DLLMANLFAQ GEALAFGKTA EEARAEGTPE
460 470 480 490 500
PLVPHRTFPG NRPSSTILAD RLTPRTLGAL VALYEHAVFT QGVIWDVDSF
510 520 530 540
DQWGVELGKV LANRIVKELE SPAEPALAHD GSTNALIRRY RARRGG
Length:546
Mass (Da):59,715
Last modified:September 23, 2008 - v1
Checksum:i7F74E70233B932E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001131 Genomic DNA Translation: ACG74399.1
RefSeqiWP_012527173.1, NC_011145.1

Genome annotation databases

EnsemblBacteriaiACG74399; ACG74399; AnaeK_3178
KEGGiank:AnaeK_3178

Similar proteinsi

Entry informationi

Entry nameiG6PI_ANASK
AccessioniPrimary (citable) accession number: B4ULW4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: February 28, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome