Reviewed, UniProtKB/Swiss-Prot B4ULW4 (G6PI_ANASK)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase
      Short name=GPI
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase
      Short name=PGI
    Phosphohexose isomerase
      Short name=PHI

Gene names

Name:	pgi
Ordered Locus Names:	AnaeK_3178

Organism

Anaeromyxobacter sp. (strain K) [Complete proteome] [HAMAP]

Taxonomic identifier

447217 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Myxococcales › Cystobacterineae › Myxococcaceae › Anaeromyxobacter

Protein attributes

Sequence length	546 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_00473 Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 546	546	Glucose-6-phosphate isomerase HAMAP MF_00473		PRO_1000125690
Sites
	Active site	389	1	By similarity
	Active site	509	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	B4ULW4-1 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 7F74E70233B932E9	FASTA	546	59,715
	10 20 30 40 50 60 MPDRTGPLLR TPAWRALEAH LAELQPLHLR ELFARDPGRG ERLVADGAGL HLDYSKQRVT 70 80 90 100 110 120 EETVRLLAAL AEARGLPERR AAMFRGEKVN VTEGRAVLHV ALRAPRGERI LVDGSDVVPE 130 140 150 160 170 180 VHAVLDRMAA FADQVRSGAW TGFTGKRIRT VVNVGIGGSD LGPAMAYRAL RAYATRDLAF 190 200 210 220 230 240 RFVSNVDGTD LAEAVRDLDP AETLFLVASK TFTTLETMTN AASARSWLLA ALGDPRAVAR 250 260 270 280 290 300 HFVAISTNEA EVRRFGIDPA NMFGFWDWVG GRYSMDSAIG LSTMIAVGPE GFRELLAGFR 310 320 330 340 350 360 EMDEHFRDAP LERNLPALIG LLGVWNANLL GAETVAVLPY DQYLDRFPAY LQQLTMESNG 370 380 390 400 410 420 KRVTASGAPV EGHGTGAIYW GEPGTNGQHS FYQLLHQGTH LVACDFIGFC RPLHALARHH 430 440 450 460 470 480 DLLMANLFAQ GEALAFGKTA EEARAEGTPE PLVPHRTFPG NRPSSTILAD RLTPRTLGAL 490 500 510 520 530 540 VALYEHAVFT QGVIWDVDSF DQWGVELGKV LANRIVKELE SPAEPALAHD GSTNALIRRY RARRGG

References

[1]

"Complete sequence of Anaeromyxobacter sp. K." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikiva G., Beliaev A. Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001131 Genomic DNA. Translation: ACG74399.1.
RefSeq	YP_002135528.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6788057.
GenomeReviews	Gene locus AnaeK_3178 in contig CP001131_GR.
KEGG	ank:AnaeK_3178.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	PYSNDLA.
Family and domain databases
HAMAP	MF_00473. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI_ANASK

Accession

Primary (citable) accession number: B4ULW4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	September 23, 2008
Last modified:	November 3, 2009
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)