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B4ULJ3 (AROC_ANASK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chorismate synthase

EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:AnaeK_0197
OrganismAnaeromyxobacter sp. (strain K) [Complete proteome] [HAMAP]
Taxonomic identifier447217 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeMyxococcaceaeAnaeromyxobacter

Protein attributes

Sequence length381 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 381381Chorismate synthase HAMAP MF_00300
PRO_1000115326

Sequences

Sequence LengthMass (Da)Tools
B4ULJ3 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 39F6FA90F576413C

FASTA38140,482
        10         20         30         40         50         60 
MTLRYLTAGE SHGPALVAIA EGFPAGLAVD FEAVDRDLRR RQKGYGRGGR MKIETDAAQF 

        70         80         90        100        110        120 
LAGLRGGLTT GAPIALAVWN KDHENWKDLV SPYARGGRKF TQVRPGHADL AGALKYGLDD 

       130        140        150        160        170        180 
ARDVLERASA RSTAVTVALG ALAKALLSTL GVEVCSRVVA IGPREIRPDA PPTPAQRDAI 

       190        200        210        220        230        240 
EASDLHVDDE ALAAEWRALI DAEKARGGSI GGAFDVYATG LPIGVGSHVH PDRRLDARLA 

       250        260        270        280        290        300 
GALCGVQAIR AVEIGDGTQV GRPGYEFHDA IHHDPARGFW RETNRAGGLE GGMTDGMPLR 

       310        320        330        340        350        360 
VRAYMKPIPT MLHPLATVDL ATRAATQARY ERSDVCAVPA AAVVGEAVVA WELANALLEK 

       370        380 
FGGDAVEDVR RAVEAYAARI R 

« Hide

References

[1]"Complete sequence of Anaeromyxobacter sp. K."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikiva G., Beliaev A.
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001131 Genomic DNA. Translation: ACG71440.1.
RefSeqYP_002132569.1. NC_011145.1.

3D structure databases

ProteinModelPortalB4ULJ3.
ModBaseSearch...

Protein-protein interaction databases

STRINGB4ULJ3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6786100.
GenomeReviewsGene locus AnaeK_0197 in contig CP001131_GR.
KEGGank:AnaeK_0197.
PATRIC20934958. VBIAnaSp90767_0199.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG292336.
OMAIQTITEN.
ProtClustDBPRK05382.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. False negative.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_ANASK
AccessionPrimary (citable) accession number: B4ULJ3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 23, 2008
Last modified: January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families