Reviewed, UniProtKB/Swiss-Prot B4ULJ3 (AROC_ANASK)

Names and origin

Protein names

Recommended name:
    Chorismate synthase
    EC=4.2.3.5
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	AnaeK_0197

Organism

Anaeromyxobacter sp. (strain K) [Complete proteome] [HAMAP]

Taxonomic identifier

447217 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Myxococcales › Cystobacterineae › Myxococcaceae › Anaeromyxobacter

Protein attributes

Sequence length	381 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity.
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 381	381	Chorismate synthase HAMAP MF_00300		PRO_1000115326

Sequences

	Sequence		Length	Mass (Da)
	B4ULJ3-1 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 39F6FA90F576413C	FASTA	381	40,482
	10 20 30 40 50 60 MTLRYLTAGE SHGPALVAIA EGFPAGLAVD FEAVDRDLRR RQKGYGRGGR MKIETDAAQF 70 80 90 100 110 120 LAGLRGGLTT GAPIALAVWN KDHENWKDLV SPYARGGRKF TQVRPGHADL AGALKYGLDD 130 140 150 160 170 180 ARDVLERASA RSTAVTVALG ALAKALLSTL GVEVCSRVVA IGPREIRPDA PPTPAQRDAI 190 200 210 220 230 240 EASDLHVDDE ALAAEWRALI DAEKARGGSI GGAFDVYATG LPIGVGSHVH PDRRLDARLA 250 260 270 280 290 300 GALCGVQAIR AVEIGDGTQV GRPGYEFHDA IHHDPARGFW RETNRAGGLE GGMTDGMPLR 310 320 330 340 350 360 VRAYMKPIPT MLHPLATVDL ATRAATQARY ERSDVCAVPA AAVVGEAVVA WELANALLEK 370 380 FGGDAVEDVR RAVEAYAARI R

References

[1]

"Complete sequence of Anaeromyxobacter sp. K." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikiva G., Beliaev A. Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001131 Genomic DNA. Translation: ACG71440.1.
RefSeq	YP_002132569.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6786100.
GenomeReviews	Gene locus AnaeK_0197 in contig CP001131_GR.
KEGG	ank:AnaeK_0197.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	IIEIFIT.
Family and domain databases
HAMAP	MF_00300. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
TIGRFAMs	TIGR00033. aroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. False negative. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_ANASK

Accession

Primary (citable) accession number: B4ULJ3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	September 23, 2008
Last modified:	November 3, 2009
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)