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B4ULJ1 (AROA_ANASK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:AnaeK_0195
OrganismAnaeromyxobacter sp. (strain K) [Complete proteome] [HAMAP]
Taxonomic identifier447217 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Myxococcales › Cystobacterineae › Myxococcaceae › Anaeromyxobacter

Protein attributes

Sequence length440 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4404403-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000099663

Sequences

Sequence LengthMass (Da)Tools
B4ULJ1 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: F23934D19E668966

FASTA44045,866
        10         20         30         40         50         60 
MSAAPTSGPL TCRRAGPLRG AIEVPGDKSI SHRSLLFGAL STGETRVTGL LDAEDVHSTR 

        70         80         90        100        110        120 
RAVEALGATV RDEGAEVVVT PPATLREPGD VIDCGNSGTS LRLLTGVLSG VPGLSVLTGD 

       130        140        150        160        170        180 
ASLRRRPVRR VIDPLRVMGA DLSARDGDRL PPVVVRGGPL RGARHLLPVA SAQVKSALLL 

       190        200        210        220        230        240 
AGLFADGETA VVEPEKSRDH TERMLRGMGV PVRVSGLEVS VSAARPAGGR VDVPGDISSA 

       250        260        270        280        290        300 
AFFLCGAAAL PGSEVTVRNL GVNETRTGLL DVLRAMGADV RLADLREVAG EPRADVTVRA 

       310        320        330        340        350        360 
DRLEGTEIRG ATIPRLIDEL PAVMVMATQA RGRTVIRDAK ELRVKESDRL AAMGETLARA 

       370        380        390        400        410        420 
GARIELFEDG CAIDGPTPLR GVEVRTRLDH RIAMAMAVAQ LFCGGEPVVL DDVACVATSF 

       430        440 
PGFFRLLDQV SGPASGGGAP

« Hide

References

[1]"Complete sequence of Anaeromyxobacter sp. K."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikiva G., Beliaev A.
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001131 Genomic DNA. Translation: ACG71438.1.
RefSeqYP_002132567.1. NC_011145.1.

3D structure databases

ProteinModelPortalB4ULJ1.
ModBaseSearch...

Protein-protein interaction databases

STRINGB4ULJ1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6786098.
GenomeReviewsGene locus AnaeK_0195 in contig CP001131_GR.
KEGGank:AnaeK_0195.
PATRIC20934954. VBIAnaSp90767_0197.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646626.
OMALECANIS.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_ANASK
AccessionPrimary (citable) accession number: B4ULJ1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 23, 2008
Last modified: January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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