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B4UEM2 (ACPS_ANASK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Holo-[acyl-carrier-protein] synthase

Short name=Holo-ACP synthase
EC=2.7.8.7
Alternative name(s):
4'-phosphopantetheinyl transferase AcpS
Gene names
Name:acpS
Ordered Locus Names:AnaeK_2366
OrganismAnaeromyxobacter sp. (strain K) [Complete proteome] [HAMAP]
Taxonomic identifier447217 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeMyxococcaceaeAnaeromyxobacter

Protein attributes

Sequence length128 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein By similarity. HAMAP MF_00101

Catalytic activity

CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein]. HAMAP MF_00101

Cofactor

Magnesium By similarity. HAMAP MF_00101

Subcellular location

Cytoplasm By similarity HAMAP MF_00101.

Sequence similarities

Belongs to the P-Pant transferase superfamily. AcpS family.

Ontologies

Keywords
   Biological processFatty acid biosynthesis
Lipid synthesis
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processfatty acid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

macromolecule biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionholo-[acyl-carrier-protein] synthase activity

Inferred from electronic annotation. Source: EC

magnesium ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 128128Holo-[acyl-carrier-protein] synthase HAMAP MF_00101
PRO_1000093853

Sites

Metal binding81Magnesium By similarity
Metal binding601Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
B4UEM2 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 5FCB6BFC6647AB55

FASTA12813,438
        10         20         30         40         50         60 
MILGLGLDVV EVARIQRILA GPPARAERFL ARVFAPSERA YCDARQDRAT RYAARFAAKE 

        70         80         90        100        110        120 
AAVKALGTPE GVRWLDLVVE RGSGAPSLAL DGLAADAARR LGVARVHLTL THDAGVAVAA 


VILEGTGP 

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References

[1]"Complete sequence of Anaeromyxobacter sp. K."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikiva G., Beliaev A.
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001131 Genomic DNA. Translation: ACG73593.1.
RefSeqYP_002134722.1. NC_011145.1.

3D structure databases

ProteinModelPortalB4UEM2.
ModBaseSearch...

Protein-protein interaction databases

STRINGB4UEM2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6783956.
GenomeReviewsGene locus AnaeK_2366 in contig CP001131_GR.
KEGGank:AnaeK_2366.
PATRIC20939387. VBIAnaSp90767_2384.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG734479.
OMAAPAGMNW.
ProtClustDBCLSK945670.

Family and domain databases

HAMAPMF_00101. AcpS.
[Tree]
InterProIPR008278. 4-PPantetheinyl_Trfase.
IPR002582. ACPS.
IPR004568. PPantethiene-prot_Trfase.
[Graphical view]
Gene3DG3DSA:3.90.470.20. G3DSA:3.90.470.20. 1 hit.
KOK00997.
PfamPF01648. ACPS. 1 hit.
[Graphical view]
ProDomPD004282. PPantethiene-prot_Trfase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF56214. 4-PPT_transf. 1 hit.
TIGRFAMsTIGR00516. AcpS. 1 hit.
TIGR00556. Pantethn_trn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameACPS_ANASK
AccessionPrimary (citable) accession number: B4UEM2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 23, 2008
Last modified: January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families