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B4UEJ2

- PGK_ANASK

UniProt

B4UEJ2 - PGK_ANASK

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Anaeromyxobacter sp. (strain K)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei37 – 371SubstrateUniRule annotation
    Binding sitei121 – 1211SubstrateUniRule annotation
    Binding sitei154 – 1541SubstrateUniRule annotation
    Binding sitei205 – 2051ATPUniRule annotation
    Binding sitei296 – 2961ATP; via carbonyl oxygenUniRule annotation
    Binding sitei327 – 3271ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi353 – 3564ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciASP447217:GHB0-2367-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:AnaeK_2336
    OrganismiAnaeromyxobacter sp. (strain K)
    Taxonomic identifieri447217 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeAnaeromyxobacteraceaeAnaeromyxobacter
    ProteomesiUP000001871: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 396396Phosphoglycerate kinasePRO_1000096320Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi447217.AnaeK_2336.

    Structurei

    3D structure databases

    ProteinModelPortaliB4UEJ2.
    SMRiB4UEJ2. Positions 4-396.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni21 – 233Substrate bindingUniRule annotation
    Regioni60 – 634Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227108.
    KOiK00927.
    OMAiWEALDIG.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4UEJ2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MALRTIDALD LAGKRVFIRV DFNVPLDPQG RVTDDARIRA ALPTIRHAIQ    50
    AKAKVILASH LGRPKGKPDD RQKLTLEPAA VRLSELLSQD VILADDCVGD 100
    GVKKLVRDLK DGHVLLLENL RFHPEEEKND EAFARELASL ADVWVNDAFG 150
    TAHRAHASTA GMARFVKEKA AGFLVQKEVE YLGKALGSPA RPFVAIVGGA 200
    KVSDKIKVLE NLIAKADAIC VGGAMAYTFL KAQGVPVGKS LVEEDKLELA 250
    RQILERAEAR KVDLLLPVDH VCGAEPKETA ERVVVNDRAI PDGLMGLDIG 300
    PKTLDRYRQR IAAAKTVFWN GPMGLFEQKP WSEGTFGVAK AMAASPAVTV 350
    VGGGDSAAAV EQAGIVDAMK HVSTGGGASL EFIEGRELPG VKACEE 396
    Length:396
    Mass (Da):42,435
    Last modified:September 23, 2008 - v1
    Checksum:iAB9077F120A0BCF0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001131 Genomic DNA. Translation: ACG73563.1.
    RefSeqiWP_012526355.1. NC_011145.1.
    YP_002134692.1. NC_011145.1.

    Genome annotation databases

    EnsemblBacteriaiACG73563; ACG73563; AnaeK_2336.
    GeneIDi6784796.
    KEGGiank:AnaeK_2336.
    PATRICi20939327. VBIAnaSp90767_2354.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001131 Genomic DNA. Translation: ACG73563.1 .
    RefSeqi WP_012526355.1. NC_011145.1.
    YP_002134692.1. NC_011145.1.

    3D structure databases

    ProteinModelPortali B4UEJ2.
    SMRi B4UEJ2. Positions 4-396.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 447217.AnaeK_2336.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACG73563 ; ACG73563 ; AnaeK_2336 .
    GeneIDi 6784796.
    KEGGi ank:AnaeK_2336.
    PATRICi 20939327. VBIAnaSp90767_2354.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227108.
    KOi K00927.
    OMAi WEALDIG.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci ASP447217:GHB0-2367-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K.

    Entry informationi

    Entry nameiPGK_ANASK
    AccessioniPrimary (citable) accession number: B4UEJ2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3