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B4UDP6 (B4UDP6_ANASK) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Ordered Locus Names:AnaeK_2235 EMBL ACG73462.1
OrganismAnaeromyxobacter sp. (strain K) [Complete proteome] [HAMAP] EMBL ACG73462.1
Taxonomic identifier447217 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeMyxococcaceaeAnaeromyxobacter

Protein attributes

Sequence length437 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity.

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
B4UDP6 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 782AB6D57DCD2A16

FASTA43748,599
        10         20         30         40         50         60 
MADAKPVVPK DGAKISLVDG KLNVPDRPIL PFIEGDGTGR DIWRASVRVL DAAVEKAYRG 

        70         80         90        100        110        120 
RRKIAWTEVY AGEKAFTKFN NWLPDETIQA FREYLIGIKG PLTTPIGGGI RSLNVALRQL 

       130        140        150        160        170        180 
LDLYVCLRPV RWFRGVPSPV KRPEKVNMVI FRENTEDIYA GIEWEAGSEQ AKKLLAFLEQ 

       190        200        210        220        230        240 
EFPKEYRKIR FPATSGVGVK PVSREGTERL VRAALEYAVR ERRRSVTFVH KGNIMKFTEG 

       250        260        270        280        290        300 
AFRNWGYALA EREFADRVYT WEQWERTKAS RGEEAANAEK QAAVAEGRIL VKDAIADITL 

       310        320        330        340        350        360 
QQVLTRPEDF DVVATPNLNG DYLSDALAAQ VGGIGIAPGG NANYVTGHAI FEATHGTAPK 

       370        380        390        400        410        420 
YADLDKVNPG SMILSGEMMF RHLGWNEAAD LIVKGVDGAI AGHRVTYDFA RLMKAEGVTD 

       430 
AVEVKCSEFG DEIIRHM 

« Hide

References

[1]"Complete sequence of Anaeromyxobacter sp. K."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikiva G., Beliaev A.
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K EMBL ACG73462.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001131 Genomic DNA. Translation: ACG73462.1.
RefSeqYP_002134591.1. NC_011145.1.

3D structure databases

ProteinModelPortalB4UDP6.
SMRB4UDP6. Positions 12-437.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING447217.AnaeK_2235.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACG73462; ACG73462; AnaeK_2235.
GeneID6785211.
KEGGank:AnaeK_2235.
PATRIC20939115. VBIAnaSp90767_2255.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0538.
HOGENOMHOG000021113.
KOK00031.
OMARYAIDND.
OrthoDBEOG6SNDTP.

Enzyme and pathway databases

BioCycASP447217:GHB0-2259-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB4UDP6_ANASK
AccessionPrimary (citable) accession number: B4UDP6
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: May 14, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)