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B4U9Q5 (B4U9Q5_HYDS0) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADPH-dependent 7-cyano-7-deazaguanine reductase HAMAP MF_00818
EC=1.7.1.13 HAMAP MF_00818
Alternative name(s):
7-cyano-7-carbaguanine reductase HAMAP MF_00818
NADPH-dependent nitrile oxidoreductase HAMAP MF_00818
PreQ(0) reductase HAMAP MF_00818
Gene names
Name:queF HAMAP MF_00818
Ordered Locus Names:HY04AAS1_1181
OrganismHydrogenobaculum sp. (strain Y04AAS1) [Complete proteome] [HAMAP]
Taxonomic identifier380749 [NCBI]
Taxonomic lineageBacteria › Aquificae › Aquificales › Aquificaceae › Hydrogenobaculum

Protein attributes

Sequence length128 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) By similarity. HAMAP MF_00818 SAAS SAAS016856

Catalytic activity

7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH. HAMAP MF_00818 SAAS SAAS016856

Pathway

tRNA modification; tRNA-queuosine biosynthesis. HAMAP MF_00818 SAAS SAAS016856

Subcellular location

Cytoplasm By similarity HAMAP MF_00818 SAAS SAAS016856.

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. HAMAP MF_00818

Sequences

Sequence LengthMass (Da)Tools
B4U9Q5 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 5F0C2CC6DB510399

FASTA12815,208
        10         20         30         40         50         60 
MQQEKKYGEI EIEKAALEPW ENPAKENDYI IEMSFPEFSC LCPRSGYPDY ATIKIRYIPN 

        70         80         90        100        110        120 
EYIVELKSLK LWLNSFRNQY ISHEAATNTI YNKLFELLKP KFLEVIGDFH PRGNLHTVVR 


VRSDKKYD

« Hide

References

[1]"Complete and draft genome sequences of six members of the Aquificales."
Reysenbach A.-L., Hamamura N., Podar M., Griffiths E., Ferreira S., Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A., Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A.
J. Bacteriol. 191:1992-1993(2009) [PubMed: 19136599] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001130 Genomic DNA. Translation: ACG57866.1.
RefSeqYP_002121844.1. NC_011126.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB4U9Q5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6743998.
GenomeReviewsGene locus HY04AAS1_1181 in contig CP001130_GR.
KEGGhya:HY04AAS1_1181.
PATRIC22137058. VBIHydSp64203_1187.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG294103.
OMAFRNAGIF.
ProtClustDBPRK13258.

Family and domain databases

HAMAPMF_00818. QueF_type1.
[Tree]
InterProIPR016856. CN_OxRdtase_NADPH-dep_QueF.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
[Graphical view]
KOK09457.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
PIRSFPIRSF027377. Nitrile_oxidored_QueF. 1 hit.
TIGRFAMsTIGR03139. QueF-II. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB4U9Q5_HYDS0
AccessionPrimary (citable) accession number: B4U9Q5
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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