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B4U9K6 (B4U9K6_HYDS0) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylaminoimidazole-succinocarboxamide synthase HAMAP MF_00137
EC=6.3.2.6 HAMAP MF_00137
Alternative name(s):
SAICAR synthetase HAMAP MF_00137
Gene names
Name:purC HAMAP MF_00137
Ordered Locus Names:HY04AAS1_1131
OrganismHydrogenobaculum sp. (strain Y04AAS1) [Complete proteome] [HAMAP]
Taxonomic identifier380749 [NCBI]
Taxonomic lineageBacteria › Aquificae › Aquificales › Aquificaceae › Hydrogenobaculum

Protein attributes

Sequence length233 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. HAMAP MF_00137 SAAS SAAS018236

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. HAMAP MF_00137 SAAS SAAS018236

Sequence similarities

Belongs to the SAICAR synthetase family. HAMAP MF_00137 RuleBase RU004193

Sequences

Sequence LengthMass (Da)Tools
B4U9K6 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: CE81306B321698A8

FASTA23326,768
        10         20         30         40         50         60 
MNKLYEGKAK IVYENDQDTY IITFKDDVTA FDAIKKDNIS GKGHINLEIT SFIFELLKAK 

        70         80         90        100        110        120 
NIKTHFIKKL SEDSMLVLKA TRIDVEVVVR NIAAGSLTKR LGIKEGTSLN PPLVELFYKS 

       130        140        150        160        170        180 
DELHDPLICI EHVKLLNLAT EEDITFMKQA ALKVNDVLKE FFDQLDIILV DFKLEFGKTK 

       190        200        210        220        230 
DGEIILIDEI SPDSCRLWDK KTGEKLDKDR FRFDLGDLKE GYLKILERIK THS

« Hide

References

[1]"Complete and draft genome sequences of six members of the Aquificales."
Reysenbach A.-L., Hamamura N., Podar M., Griffiths E., Ferreira S., Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A., Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A.
J. Bacteriol. 191:1992-1993(2009) [PubMed: 19136599] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001130 Genomic DNA. Translation: ACG57817.1.
RefSeqYP_002121795.1. NC_011126.1.

3D structure databases

ProteinModelPortalB4U9K6.
SMRB4U9K6. Positions 3-230.
ModBaseSearch...

Protein-protein interaction databases

STRINGB4U9K6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6743947.
GenomeReviewsGene locus HY04AAS1_1131 in contig CP001130_GR.
KEGGhya:HY04AAS1_1131.
PATRIC22136958. VBIHydSp64203_1138.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG306070.
OMAYKDDALG.

Family and domain databases

HAMAPMF_00137. SAICAR_synth.
[Tree]
InterProIPR013816. ATP_grasp_subdomain_2.
IPR001636. SAICAR_synth.
IPR018236. SAICAR_synthetase_CS.
[Graphical view]
Gene3DG3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit.
KOK01923.
PANTHERPTHR11609. SAICAR_synt. 1 hit.
PfamPF01259. SAICAR_synt. 1 hit.
[Graphical view]
TIGRFAMsTIGR00081. PurC. 1 hit.
PROSITEPS01058. SAICAR_SYNTHETASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB4U9K6_HYDS0
AccessionPrimary (citable) accession number: B4U9K6
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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