Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

B4U983 (B4U983_HYDS0) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201

EC=5.1.1.1 HAMAP-Rule MF_01201
Gene names
Ordered Locus Names:HY04AAS1_1008 EMBL ACG57694.1
OrganismHydrogenobaculum sp. (strain Y04AAS1) [Complete proteome] [HAMAP] EMBL ACG57694.1
Taxonomic identifier380749 [NCBI]
Taxonomic lineageBacteriaAquificaeAquificalesAquificaceaeHydrogenobaculum

Protein attributes

Sequence length343 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site321Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2401Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1261Substrate By similarity HAMAP-Rule MF_01201
Binding site2881Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue321N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
B4U983 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 2EBEEC04C05C932D

FASTA34338,393
        10         20         30         40         50         60 
MRIVLELLKE NILNNISQIY NSVNKPIIAV VKANAYGMGS AEVSKVLDDN PYVKSFAVAC 

        70         80         90        100        110        120 
IEEAVELREV DVKKPILVLG GVLDLKDVEY LKHYKLTPVI SSAYQFDMIK NAGIDFHVKL 

       130        140        150        160        170        180 
DTGMGRLGFF ELQEDIIGHP NLKGIMTHLA SPLDKDYSAF QIQKFKNIVK SLKRNSIEIH 

       190        200        210        220        230        240 
YQSSAGLMYE KDFTTAIRIG LAMYGEKPYE GFDIPIKPIY KVKAKVISLK NFKKGDKISY 

       250        260        270        280        290        300 
GGTYTLTKDA TIGVVSMGYA DGIPKSLANK WYFDFNGAKL PMVGAVTMDM TMFELPEGVN 

       310        320        330        340 
IKIGDYVDFV NEGQTFSMAS KIVKTIPYEL MCRMGKRVKR VVV 

« Hide

References

[1]"Complete and draft genome sequences of six members of the Aquificales."
Reysenbach A.L., Hamamura N., Podar M., Griffiths E., Ferreira S., Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A., Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A.
J. Bacteriol. 191:1992-1993(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Y04AAS1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001130 Genomic DNA. Translation: ACG57694.1.
RefSeqYP_002121672.1. NC_011126.1.

3D structure databases

ProteinModelPortalB4U983.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING380749.HY04AAS1_1008.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACG57694; ACG57694; HY04AAS1_1008.
GeneID6743820.
KEGGhya:HY04AAS1_1008.
PATRIC22136706. VBIHydSp64203_1016.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMARDLELCS.
OrthoDBEOG6PP9NJ.
ProtClustDBCLSK2299837.

Enzyme and pathway databases

BioCycHSP380749:GH30-1042-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB4U983_HYDS0
AccessionPrimary (citable) accession number: B4U983
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: April 16, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)