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B4U983

- B4U983_HYDS0

UniProt

B4U983 - B4U983_HYDS0

Protein

Alanine racemase

Gene

HY04AAS1_1008

Organism
Hydrogenobaculum sp. (strain Y04AAS1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei32 – 321Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei126 – 1261SubstrateUniRule annotation
    Active sitei240 – 2401Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei288 – 2881Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciHSP380749:GH30-1042-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:HY04AAS1_1008Imported
    OrganismiHydrogenobaculum sp. (strain Y04AAS1)Imported
    Taxonomic identifieri380749 [NCBI]
    Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeHydrogenobaculum
    ProteomesiUP000001872: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei32 – 321N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi380749.HY04AAS1_1008.

    Structurei

    3D structure databases

    ProteinModelPortaliB4U983.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiISHFACA.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B4U983-1 [UniParc]FASTAAdd to Basket

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    MRIVLELLKE NILNNISQIY NSVNKPIIAV VKANAYGMGS AEVSKVLDDN    50
    PYVKSFAVAC IEEAVELREV DVKKPILVLG GVLDLKDVEY LKHYKLTPVI 100
    SSAYQFDMIK NAGIDFHVKL DTGMGRLGFF ELQEDIIGHP NLKGIMTHLA 150
    SPLDKDYSAF QIQKFKNIVK SLKRNSIEIH YQSSAGLMYE KDFTTAIRIG 200
    LAMYGEKPYE GFDIPIKPIY KVKAKVISLK NFKKGDKISY GGTYTLTKDA 250
    TIGVVSMGYA DGIPKSLANK WYFDFNGAKL PMVGAVTMDM TMFELPEGVN 300
    IKIGDYVDFV NEGQTFSMAS KIVKTIPYEL MCRMGKRVKR VVV 343
    Length:343
    Mass (Da):38,393
    Last modified:September 23, 2008 - v1
    Checksum:i2EBEEC04C05C932D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001130 Genomic DNA. Translation: ACG57694.1.
    RefSeqiWP_012514050.1. NC_011126.1.
    YP_002121672.1. NC_011126.1.

    Genome annotation databases

    EnsemblBacteriaiACG57694; ACG57694; HY04AAS1_1008.
    GeneIDi6743820.
    KEGGihya:HY04AAS1_1008.
    PATRICi22136706. VBIHydSp64203_1016.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001130 Genomic DNA. Translation: ACG57694.1 .
    RefSeqi WP_012514050.1. NC_011126.1.
    YP_002121672.1. NC_011126.1.

    3D structure databases

    ProteinModelPortali B4U983.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 380749.HY04AAS1_1008.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACG57694 ; ACG57694 ; HY04AAS1_1008 .
    GeneIDi 6743820.
    KEGGi hya:HY04AAS1_1008.
    PATRICi 22136706. VBIHydSp64203_1016.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi ISHFACA.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci HSP380749:GH30-1042-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Y04AAS1Imported.

    Entry informationi

    Entry nameiB4U983_HYDS0
    AccessioniPrimary (citable) accession number: B4U983
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3