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B4U737 (B4U737_HYDS0) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase subunit beta HAMAP MF_01321
Short name=RNAP subunit beta HAMAP MF_01321
EC=2.7.7.6 HAMAP MF_01321
Alternative name(s):
RNA polymerase subunit beta HAMAP MF_01321
Transcriptase subunit beta HAMAP MF_01321
Gene names
Name:rpoB HAMAP MF_01321
Ordered Locus Names:HY04AAS1_0258
OrganismHydrogenobaculum sp. (strain Y04AAS1) [Complete proteome] [HAMAP]
Taxonomic identifier380749 [NCBI]
Taxonomic lineageBacteria › Aquificae › Aquificales › Aquificaceae › Hydrogenobaculum

Protein attributes

Sequence length1470 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates By similarity. HAMAP MF_01321 RuleBase RU000432

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_01321

Subunit structure

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity. HAMAP MF_01321 RuleBase RU000433

Sequence similarities

Belongs to the RNA polymerase beta chain family. HAMAP MF_01321 RuleBase RU000434

Sequences

Sequence LengthMass (Da)Tools
B4U737 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 160EF07FCC712028

FASTA1,470166,858
        10         20         30         40         50         60 
MLKLKHAIPR KFFGRRSELL DLPFLVKVPT ESFENFIQFN VPPTKRKEQG LEYILRTSFP 

        70         80         90        100        110        120 
FQDTNKNITV EYIGYEIGNW ECNKCGYKPE TDFLAGADTE CPKCKTILSY KEKYTPEECK 

       130        140        150        160        170        180 
EKGITYSAPI RIMLRLRKKT KSGEFVDTPK KIYFGEMPMM TPIGTFVING SERVVVNQLI 

       190        200        210        220        230        240 
RSPGIFYSDK EDRQKEGTVS RTIFTASIHP DKGSRIEFEL STNSDIISAR IDKKRISAIS 

       250        260        270        280        290        300 
ILRAFGLETA YDILSQFYED VKAFNVKDGL IIDKNTGEVY KPEDLESHYL FAVLRYTAKI 

       310        320        330        340        350        360 
EGTEKEEEFI EERYIEDLNV LNRLIKDERV KIELLTAVQS EKTTKSFYGK IILETLINDT 

       370        380        390        400        410        420 
KAKDQHGKSL VRTNSQFTLR DIGLRDIYVK LRSMEGLVQE MADIIQRSRA YFEAYFQDIA 

       430        440        450        460        470        480 
RFDLSKVGRV KINAKIYIHK RELTEKDLEI FDELPVLELA KDYDNYKEGT ILTKDIFEYI 

       490        500        510        520        530        540 
LKSHKTIEVR DYTGLEARFL NHKDLVNAIK YLLKVRFGKE KKDDIAHLGN RRVRPIGELL 

       550        560        570        580        590        600 
ENQARIGIAR MLKSFRDKVA TINPEDPTIK AQDLVNSRYL VSSMFEFLKG GQLSQYLDNS 

       610        620        630        640        650        660 
NPLSSLTHRR RLSALGPGGL TRESAKFEIR DVHPSHYGRL CPIETPEGQN IGLVTSMTTY 

       670        680        690        700        710        720 
AQTNEYGFLV TPYRKVENGI VTDQIEFLAA YEEENFVIAQ STPTDQKGKI LGDRLIARYK 

       730        740        750        760        770        780 
NDIQIVKPSD VNYIDVSPRQ IISVSASLIP FLEHDDANRA LMGSNMQRQA VPLIFTQAPL 

       790        800        810        820        830        840 
IGTGMESKVA IDSGAAILAK RGGVVEEVDS NRIVIRVNPN EINEKDPLDM GIDVYKLLKF 

       850        860        870        880        890        900 
TKTNQNTSVN QRPIVYKGQK IKKGDCIADG QSTFMGELAL GKDLLVCFMP WRGYNFEDAI 

       910        920        930        940        950        960 
VISERLVKED VLTSVHIEEL KAEARETKIG DEEITRQVPG VSEKALAYLD EYGIVKVGTY 

       970        980        990       1000       1010       1020 
VKPGDILVGK VTPIGETQLT PEQKLLQAIF GEKTRDVKDS SLRCPPGIEG VVVDVQVFTR 

      1030       1040       1050       1060       1070       1080 
KLSESKKNPL VEHVEQEEKN RIKKEKEFML NLVIEKRNEI VKDLVIGKVI NKPIKLAKKT 

      1090       1100       1110       1120       1130       1140 
YEEGTVIDEA LFDNIANFVI TKPENFFSDK KLIKKIEEIR DKAQAQRKVI DKIYEEKIEN 

      1150       1160       1170       1180       1190       1200 
VGKQSDLPSG VITMVKVYIA QKRKIRVGDK MAGRHGNKGV ISVVLPVEDM PFLPDGTPVD 

      1210       1220       1230       1240       1250       1260 
VVLNPLGVPS RMNVGQILET HLGMASKYIG KKVQEMIDEY FNRDEITEYI ASIYAIGDKN 

      1270       1280       1290       1300       1310       1320 
NENKNFIKNM LKSLSDEEFK NVVSFVAQNG IPIATPAFEG CSEDDLKTLL KEAGLPEDGK 

      1330       1340       1350       1360       1370       1380 
FVLYDGRTGE PFDFRVTTGY MHMLKLIHMV EDKIHARSTG PYSLVTQQPL GGRAQFGGQR 

      1390       1400       1410       1420       1430       1440 
LGEMEVWALE AHGAAYTLQE MLTVKSDDIE GRNRAYESIV KGKYFYSPGI PESFKVLVRE 

      1450       1460       1470 
LKSLGLNVVC ENGEAKSCDS VDLDKKEEER

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References

[1]"Complete and draft genome sequences of six members of the Aquificales."
Reysenbach A.-L., Hamamura N., Podar M., Griffiths E., Ferreira S., Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A., Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A.
J. Bacteriol. 191:1992-1993(2009) [PubMed: 19136599] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001130 Genomic DNA. Translation: ACG56948.1.
RefSeqYP_002120926.1. NC_011126.1.

3D structure databases

ProteinModelPortalB4U737.
ModBaseSearch...

Protein-protein interaction databases

STRINGB4U737.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6743052.
GenomeReviewsGene locus HY04AAS1_0258 in contig CP001130_GR.
KEGGhya:HY04AAS1_0258.
PATRIC22135154. VBIHydSp64203_0256.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG285547.
OMAIGRNKTY.
ProtClustDBPRK00405.

Family and domain databases

HAMAPMF_01321. RNApol_bact_RpoB.
[Tree]
InterProIPR010243. DNA-dir_RNA_pol_bsu_bac-type.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
Gene3DG3DSA:2.30.150.10. G3DSA:2.30.150.10. 1 hit.
G3DSA:2.40.270.10. G3DSA:2.40.270.10. 2 hits.
G3DSA:2.40.50.150. Ribosomal_L2. 2 hits.
KOK03043.
PANTHERPTHR20856:SF3. PTHR20856:SF3. 1 hit.
PTHR20856. RNA_pol_I_sub2. 1 hit.
PfamPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 2 hits.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsTIGR02013. RpoB. 1 hit.
PROSITEPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB4U737_HYDS0
AccessionPrimary (citable) accession number: B4U737
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info