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B4U6E8 (B4U6E8_HYDS0) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
2-dehydro-3-deoxyphosphooctonate aldolase HAMAP MF_00056
EC=2.5.1.55 HAMAP MF_00056
Alternative name(s):
3-deoxy-D-manno-octulosonic acid 8-phosphate synthase HAMAP MF_00056
KDO-8-phosphate synthase HAMAP MF_00056
Phospho-2-dehydro-3-deoxyoctonate aldolase HAMAP MF_00056
Gene names
Name:kdsA HAMAP MF_00056
Ordered Locus Names:HY04AAS1_1603
OrganismHydrogenobaculum sp. (strain Y04AAS1) [Complete proteome] [HAMAP]
Taxonomic identifier380749 [NCBI]
Taxonomic lineageBacteria › Aquificae › Aquificales › Aquificaceae › Hydrogenobaculum

Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate. HAMAP MF_00056 SAAS SAAS006269

Pathway

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP MF_00056 SAAS SAAS006269

Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3. HAMAP MF_00056 SAAS SAAS006269

Subcellular location

Cytoplasm By similarity HAMAP MF_00056 SAAS SAAS006269.

Sequence similarities

Belongs to the KdsA family. HAMAP MF_00056

Sequences

Sequence LengthMass (Da)Tools
B4U6E8 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 2994FD3B2AFB83C8

FASTA26529,490
        10         20         30         40         50         60 
MEKKFLIIAG PCVIESYELC FEVASHLKEF SLKYKEFDFV FKASFDKANR TSVNSYRGPG 

        70         80         90        100        110        120 
LEKGLEILKR IKEEFSMPVT TDVHETYQVK PVAEVVDIIQ IPAFLCRQTD LLLAAAETGK 

       130        140        150        160        170        180 
SVNVKKGQFL APWDTKYIID KLKSKNKDAT FYLTERGSSF GYNNLVVDMR SLPIMRQYAK 

       190        200        210        220        230        240 
VIFDATHSVQ LPGGAGGSSS GQREFVPYLI RAAVAVGVDG VFMETHPNPE KALSDGPNSI 

       250        260 
PLKDLEGILI QIKAIKQALD DINQS

« Hide

References

[1]"Complete and draft genome sequences of six members of the Aquificales."
Reysenbach A.-L., Hamamura N., Podar M., Griffiths E., Ferreira S., Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A., Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A.
J. Bacteriol. 191:1992-1993(2009) [PubMed: 19136599] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001130 Genomic DNA. Translation: ACG58284.1.
RefSeqYP_002122262.1. NC_011126.1.

3D structure databases

ProteinModelPortalB4U6E8.
SMRB4U6E8. Positions 3-257.
ModBaseSearch...

Protein-protein interaction databases

STRINGB4U6E8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6744435.
GenomeReviewsGene locus HY04AAS1_1603 in contig CP001130_GR.
KEGGhya:HY04AAS1_1603.
PATRIC22137930. VBIHydSp64203_1608.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG575990.
OMACVIESLE.
ProtClustDBPRK05198.

Family and domain databases

HAMAPMF_00056. KDO8P_synth.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006269. KDO8P_synthase.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01627.
PANTHERPTHR21057:SF2. KDO8P_synthase. 1 hit.
PfamPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR01362. KDO8P_synth. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB4U6E8_HYDS0
AccessionPrimary (citable) accession number: B4U6E8
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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