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Protein

Uronate isomerase

Gene

uxaC

Organism
Streptococcus equi subsp. zooepidemicus (strain MGCS10565)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciSEQU552526:GH4P-717-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:Sez_0689
OrganismiStreptococcus equi subsp. zooepidemicus (strain MGCS10565)
Taxonomic identifieri552526 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000001873 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 465465Uronate isomerasePRO_1000131610Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliB4U237.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

B4U237-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFNDDNFML KNEAAKRLYQ QIKDQPIFDY HCHLDPKEIF EDKVYDNIVD
60 70 80 90 100
LWLGGDHYKW RLMRANGISE EEITGSASKL DKFKAFARTL QRSYGNPVYH
110 120 130 140 150
WSVMELKNVF GVCELLTEDN AEEIYHRINA YLVEHQISPR KLIADSRVRF
160 170 180 190 200
IGTTDHPLDD LAWHKRLTAD DTFETVVAPT FRPDEAFIEH QRFADFVARL
210 220 230 240 250
AQATGRTITD FKSFIAAMEE RIAYFAENGC KASDISFTEI VFEAAEPEQL
260 270 280 290 300
DRLMTRVLEG YQPQPLEIKQ WQTAVFAELC RLYKHYGFVT QVHFGALRNN
310 320 330 340 350
HSAIFNKLGA DVGVDSLGDQ AALAINMNRL LDHLVQRDSL PKMIWYNLNP
360 370 380 390 400
SYNITVPNTL ANFQANENGI AGYLQFGAGW WFADTKLGMI SQMNALAEQG
410 420 430 440 450
LLANFVGMLT DSRSFLSYQR HDYFRRILST YLGEWIEEGE VPEDYQVLGS
460
MAKDIAYNNA IQYFS
Length:465
Mass (Da):53,543
Last modified:September 23, 2008 - v1
Checksum:i137991F9F6EB3796
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001129 Genomic DNA. Translation: ACG62054.1.
RefSeqiWP_012515330.1. NC_011134.1.

Genome annotation databases

EnsemblBacteriaiACG62054; ACG62054; Sez_0689.
KEGGisez:Sez_0689.
PATRICi19655297. VBIStrEqu17662_0713.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001129 Genomic DNA. Translation: ACG62054.1.
RefSeqiWP_012515330.1. NC_011134.1.

3D structure databases

ProteinModelPortaliB4U237.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACG62054; ACG62054; Sez_0689.
KEGGisez:Sez_0689.
PATRICi19655297. VBIStrEqu17662_0713.

Phylogenomic databases

HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciSEQU552526:GH4P-717-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_STREM
AccessioniPrimary (citable) accession number: B4U237
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: September 7, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.