B4U1B3FABH_STREMBeta-ketoacyl-[acyl-carrier-protein] synthase IIIBeta-ketoacyl-ACP synthase IIIKAS III2.3.1.1803-oxoacyl-[acyl-carrier-protein] synthase 33-oxoacyl-[acyl-carrier-protein] synthase IIIfabHSez_0406Streptococcus equi subsp. zooepidemicus (strain MGCS10565)BacteriaBacillotaBacilliLactobacillalesStreptococcaceaeStreptococcusGenome sequence of a lancefield group C Streptococcus zooepidemicus strain causing epidemic nephritis: new information about an old disease.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoALipid metabolism; fatty acid biosynthesis.Homodimer.CytoplasmThe last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.Belongs to the thiolase-like superfamily. FabH family.AcyltransferaseCytoplasmFatty acid biosynthesisFatty acid metabolismLipid biosynthesisLipid metabolismMultifunctional enzymeTransferaseMVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRHISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATNAFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDGAGGVLLEASEQQHFLAEALHTDGARSQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIFDFAIRDVSRSIAAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMHYGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI
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