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Protein

Ribosomal RNA large subunit methyltransferase F

Gene

rlmF

Organism
Salmonella schwarzengrund (strain CVM19633)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 1618 of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciSENT439843:GHHR-2781-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase FUniRule annotation (EC:2.1.1.181UniRule annotation)
Alternative name(s):
23S rRNA mA1618 methyltransferaseUniRule annotation
rRNA adenine N-6-methyltransferaseUniRule annotation
Gene namesi
Name:rlmFUniRule annotation
Ordered Locus Names:SeSA_A0974
OrganismiSalmonella schwarzengrund (strain CVM19633)
Taxonomic identifieri439843 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001865 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 308308Ribosomal RNA large subunit methyltransferase FPRO_1000188535Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. METTL16/RlmF family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000218605.
KOiK06970.
OMAiTEFHQGH.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F. 1 hit.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 1 hit.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

B4TQW9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAQKSGLHP RNRHQHRYDL AALCQTTPEL TSFLIRTPAG EQSVDFANPQ
60 70 80 90 100
AVKALNKALL AHFYAVTHWD IPPGFLCPPV PGRADYIHHL ADLLGETTGS
110 120 130 140 150
IPAQATILDV GVGANCIYPL IGVHEYGWRF TGSEVSDAAM SSAQAIIQAN
160 170 180 190 200
TGLSRAIRLR RQKDPAAIFT GIIHKNEFYD ATLCNPPFHD SAAAARAGSE
210 220 230 240 250
RKRRNLGQNK DDALNFGGQQ QELWCEGGEV AFIKKMIAES QSFRRQVLWF
260 270 280 290 300
TTLVSRGENL PPLYRALTEA GAVKVVKKEM AQGQKQSRFI AWTFMDDDQR

RRFITRKR
Length:308
Mass (Da):34,300
Last modified:September 23, 2008 - v1
Checksum:i45E2ABEEEC9F9149
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001127 Genomic DNA. Translation: ACF91322.1.
RefSeqiWP_001275974.1. NC_011094.1.

Genome annotation databases

EnsemblBacteriaiACF91322; ACF91322; SeSA_A0974.
KEGGisew:SeSA_A0974.
PATRICi32370606. VBISalEnt87589_1059.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001127 Genomic DNA. Translation: ACF91322.1.
RefSeqiWP_001275974.1. NC_011094.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACF91322; ACF91322; SeSA_A0974.
KEGGisew:SeSA_A0974.
PATRICi32370606. VBISalEnt87589_1059.

Phylogenomic databases

HOGENOMiHOG000218605.
KOiK06970.
OMAiTEFHQGH.

Enzyme and pathway databases

BioCyciSENT439843:GHHR-2781-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F. 1 hit.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 1 hit.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRLMF_SALSV
AccessioniPrimary (citable) accession number: B4TQW9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: September 23, 2008
Last modified: September 7, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.