B4TQT0 (6PGL_SALSV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
6-phosphogluconolactonase
Short name=6-P-gluconolactonase
EC=3.1.1.31

Gene names

Name:	pgl
Ordered Locus Names:	SeSA_A0935

Organism

Salmonella schwarzengrund (strain CVM19633) [Complete proteome] [HAMAP]

Taxonomic identifier

439843 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity. HAMAP MF_01605
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605
Sequence similarities	Belongs to the cycloisomerase 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	6-phosphogluconolactonase HAMAP MF_01605		PRO_1000148168

Sequences

	Sequence		Length	Mass (Da)
	B4TQT0 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 240B46DF97002DD5	FASTA	331	36,337
	10 20 30 40 50 60 MKQTVYTASP ESQQIHVWSL NHEGTLTLVQ VVDVPGQVQP MVVSPDKRYL YVGVRPEFRV 70 80 90 100 110 120 LAYRIAPDDG ALTFAAESAL PGSPTHISTD HHGRFVFVGS YNAGNVSVTR LQDGLPVELV 130 140 150 160 170 180 DVVEGLDGCH SANITPDNRT LWVPALKQDR ICLFTLSDDG HLVAQEPAEV NTVEGAGPRH 190 200 210 220 230 240 MVFHPNRQYA YCVNELNSSV DVWQLKNPHG EIECVQTLDM MPADFSDTRW AADIHITPDG 250 260 270 280 290 300 RHLYACDRTA SLITVFSVSE DGSVLSVEGF QPTEAQPRGF NIDNSGKYLI AAGQKSHHIA 310 320 330 VYEITGTQGL LTEKGRYAVG QGPMWVVVNA Y

References

[1]

"Complete genome of Salmonella schwarzengrund strain CVM19633." Ravel J., Fricke W.F., White D., McDermott P., Mammel M., Rosovitz M., Leclerc J., Cebula T., Sebastian Y. Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CVM19633.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001127 Genomic DNA. Translation: ACF90941.1.
RefSeq	YP_002113878.1. NC_011094.1.
3D structure databases
ProteinModelPortal	B4TQT0.
SMR	B4TQT0. Positions 1-331.
ModBase	Search...
Protein-protein interaction databases
STRING	B4TQT0.
Proteomic databases
PRIDE	B4TQT0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6518718.
GenomeReviews	Gene locus SeSA_A0935 in contig CP001127_GR.
KEGG	sew:SeSA_A0935.
PATRIC	32370524. VBISalEnt87589_1018.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG741123.
OMA	FLISAGQ.
ProtClustDB	PRK11028.
Family and domain databases
HAMAP	MF_01605. 6P-gluconolactonase. [Tree]
InterPro	IPR022528. 6-phosphogluconolactonase_YbhE. IPR019405. Lactonase_7-beta_prop. IPR011045. N2O_reductase_N. IPR015943. WD40/YVTN_repeat-like_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
KO	K07404.
Pfam	PF10282. Lactonase. 1 hit. [Graphical view]
SUPFAM	SSF50974. N2O_reductase_N. 1 hit.
ProtoNet	Search...

Entry information

Entry name

6PGL_SALSV

Accession

Primary (citable) accession number: B4TQT0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	September 23, 2008
Last modified:	January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program