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B4TPH8 (NUDI_SALSV) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nucleoside triphosphatase NudI

EC=3.6.1.-
Gene names
Name:nudI
Ordered Locus Names:SeSA_A2523
OrganismSalmonella schwarzengrund (strain CVM19633) [Complete proteome] [HAMAP]
Taxonomic identifier439843 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Protein attributes

Sequence length141 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) By similarity. HAMAP-Rule MF_01846

Catalytic activity

Nucleoside triphosphate + H2O = nucleoside monophosphate + diphosphate. HAMAP-Rule MF_01846

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01846

Subunit structure

Monomer By similarity. HAMAP-Rule MF_01846

Sequence similarities

Belongs to the Nudix hydrolase family. NudI subfamily.

Contains 1 nudix hydrolase domain.

Ontologies

Keywords
   LigandMagnesium
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

triphosphatase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 141141Nucleoside triphosphatase NudI HAMAP-Rule MF_01846
PRO_1000188494

Regions

Domain1 – 141141Nudix hydrolase
Motif38 – 5922Nudix box HAMAP-Rule MF_01846

Sequences

Sequence LengthMass (Da)Tools
B4TPH8 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 7C717C5592A42AAE

FASTA14116,274
        10         20         30         40         50         60 
MRQRTIVCPL IQNDGCYLLC KMADNRGVFP GQWALSGGGV EPGERIEEAL RREVREELGE 

        70         80         90        100        110        120 
QLILSDITPW TFRDDIRVKT YADGRQEEIY MIYLIFDCVS ANRDICINDE FQDYAWVKPE 

       130        140 
ELALYDLNVA TRHTLALKGL L 

« Hide

References

[1]"Complete genome of Salmonella schwarzengrund strain CVM19633."
Ravel J., Fricke W.F., White D., McDermott P., Mammel M., Rosovitz M., Leclerc J., Cebula T., Sebastian Y.
Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CVM19633.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001127 Genomic DNA. Translation: ACF90643.1.
RefSeqYP_002115365.1. NC_011094.1.

3D structure databases

ProteinModelPortalB4TPH8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING439843.SeSA_A2523.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACF90643; ACF90643; SeSA_A2523.
PATRIC32373687. VBISalEnt87589_2581.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0494.
HOGENOMHOG000059287.
OMANEEFDDY.
OrthoDBEOG6GN73N.
ProtClustDBPRK15472.

Enzyme and pathway databases

BioCycSENT439843:GHHR-2082-MONOMER.

Family and domain databases

Gene3D3.90.79.10. 1 hit.
HAMAPMF_01846. Nudix_NudI.
InterProIPR023781. Nucleoside_triphosphatase_NudI.
IPR020476. Nudix_hydrolase.
IPR020084. NUDIX_hydrolase_CS.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
[Graphical view]
PfamPF00293. NUDIX. 1 hit.
[Graphical view]
PRINTSPR00502. NUDIXFAMILY.
SUPFAMSSF55811. SSF55811. 1 hit.
PROSITEPS51462. NUDIX. 1 hit.
PS00893. NUDIX_BOX. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNUDI_SALSV
AccessionPrimary (citable) accession number: B4TPH8
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: September 23, 2008
Last modified: April 16, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families