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Protein

Nucleoside triphosphatase NudI

Gene

nudI

Organism
Salmonella schwarzengrund (strain CVM19633)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).UniRule annotation

Catalytic activityi

Nucleoside triphosphate + H2O = nucleoside monophosphate + diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. triphosphatase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciSENT439843:GHHR-2082-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoside triphosphatase NudIUniRule annotation (EC:3.6.1.-UniRule annotation)
Gene namesi
Name:nudIUniRule annotation
Ordered Locus Names:SeSA_A2523
OrganismiSalmonella schwarzengrund (strain CVM19633)
Taxonomic identifieri439843 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001865: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 141141Nucleoside triphosphatase NudIPRO_1000188494Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi439843.SeSA_A2523.

Structurei

3D structure databases

ProteinModelPortaliB4TPH8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 141141Nudix hydrolaseUniRule annotationAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi38 – 5922Nudix boxAdd
BLAST

Sequence similaritiesi

Belongs to the Nudix hydrolase family. NudI subfamily.UniRule annotation
Contains 1 nudix hydrolase domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0494.
HOGENOMiHOG000059287.
OMAiNEEFDDY.
OrthoDBiEOG6GN73N.

Family and domain databases

Gene3Di3.90.79.10. 1 hit.
HAMAPiMF_01846. Nudix_NudI.
InterProiIPR023781. Nucleoside_triphosphatase_NudI.
IPR020476. Nudix_hydrolase.
IPR020084. NUDIX_hydrolase_CS.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
[Graphical view]
PfamiPF00293. NUDIX. 1 hit.
[Graphical view]
PRINTSiPR00502. NUDIXFAMILY.
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiPS51462. NUDIX. 1 hit.
PS00893. NUDIX_BOX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4TPH8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRQRTIVCPL IQNDGCYLLC KMADNRGVFP GQWALSGGGV EPGERIEEAL
60 70 80 90 100
RREVREELGE QLILSDITPW TFRDDIRVKT YADGRQEEIY MIYLIFDCVS
110 120 130 140
ANRDICINDE FQDYAWVKPE ELALYDLNVA TRHTLALKGL L
Length:141
Mass (Da):16,274
Last modified:September 23, 2008 - v1
Checksum:i7C717C5592A42AAE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001127 Genomic DNA. Translation: ACF90643.1.
RefSeqiYP_002115365.1. NC_011094.1.

Genome annotation databases

EnsemblBacteriaiACF90643; ACF90643; SeSA_A2523.
PATRICi32373687. VBISalEnt87589_2581.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001127 Genomic DNA. Translation: ACF90643.1.
RefSeqiYP_002115365.1. NC_011094.1.

3D structure databases

ProteinModelPortaliB4TPH8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi439843.SeSA_A2523.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACF90643; ACF90643; SeSA_A2523.
PATRICi32373687. VBISalEnt87589_2581.

Phylogenomic databases

eggNOGiCOG0494.
HOGENOMiHOG000059287.
OMAiNEEFDDY.
OrthoDBiEOG6GN73N.

Enzyme and pathway databases

BioCyciSENT439843:GHHR-2082-MONOMER.

Family and domain databases

Gene3Di3.90.79.10. 1 hit.
HAMAPiMF_01846. Nudix_NudI.
InterProiIPR023781. Nucleoside_triphosphatase_NudI.
IPR020476. Nudix_hydrolase.
IPR020084. NUDIX_hydrolase_CS.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
[Graphical view]
PfamiPF00293. NUDIX. 1 hit.
[Graphical view]
PRINTSiPR00502. NUDIXFAMILY.
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiPS51462. NUDIX. 1 hit.
PS00893. NUDIX_BOX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative genomics of 28 Salmonella enterica isolates: evidence for CRISPR-mediated adaptive sublineage evolution."
    Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G., Leclerc J.E., Ravel J., Cebula T.A.
    J. Bacteriol. 193:3556-3568(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CVM19633.

Entry informationi

Entry nameiNUDI_SALSV
AccessioniPrimary (citable) accession number: B4TPH8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: September 23, 2008
Last modified: January 7, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.