B4TNH8 (DCD_SALSV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	SeSA_A2355

Organism

Salmonella schwarzengrund (strain CVM19633) [Complete proteome] [HAMAP]

Taxonomic identifier

439843 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella choleraesuis › Salmonella enterica I › Salmonella enterica subsp. enterica serovar Schwarzengrund

Protein attributes

Sequence length	193 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 193	193	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000096453

Sequences

	Sequence		Length	Mass (Da)
	B4TNH8 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: AB38D537A3B501A6	FASTA	193	21,236
	10 20 30 40 50 60 MRLCDRDIEA WLDEGRLSIT PRPPVERING ATVDVRLGNK FRTFRGHTAA FIDLSGPKDE 70 80 90 100 110 120 VSAALDRVMS DEIVLPDGEA FYLHPGELAL AVTFESVTLP PDLVGWLDGR SSLARLGLMV 130 140 150 160 170 180 HVTAHRIDPG WSGCIVLEFY NSGKLPLALR PGMLIGALSF EPLSGPAARP YNRRQDAKYR 190 DQQGAVASRI DKD

References

[1]

"Complete genome of Salmonella schwarzengrund strain CVM19633." Ravel J., Fricke W.F., White D., McDermott P., Mammel M., Rosovitz M., Leclerc J., Cebula T., Sebastian Y. Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CVM19633.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001127 Genomic DNA. Translation: ACF90906.1.
RefSeq	YP_002115210.1. NC_011094.1.
3D structure databases
ProteinModelPortal	B4TNH8.
SMR	B4TNH8. Positions 1-193.
ModBase	Search...
Protein-protein interaction databases
STRING	439843.SeSA_A2355.
Proteomic databases
PRIDE	B4TNH8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACF90906; ACF90906; SeSA_A2355.
GeneID	6517085.
KEGG	sew:SeSA_A2355.
PATRIC	32373348. VBISalEnt87589_2413.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228601.
KO	K01494.
OMA	RQDAKYK.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	SENT439843:GHHR-2353-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_SALSV

Accession

Primary (citable) accession number: B4TNH8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	September 23, 2008
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program