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Protein

Glutamate-ammonia-ligase adenylyltransferase

Gene

glnE

Organism
Salmonella heidelberg (strain SL476)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Adenylation and deadenylation of glutamate--ammonia ligase.UniRule annotation

Catalytic activityi

ATP + [glutamine synthetase]-L-tyrosine = diphosphate + [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

ATP-binding, Magnesium, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate-ammonia-ligase adenylyltransferaseUniRule annotation (EC:2.7.7.42UniRule annotation)
Alternative name(s):
Glutamine-synthetase adenylyltransferase
Short name:
ATaseUniRule annotation
[Glutamate--ammonia-ligase] adenylyltransferaseUniRule annotation
Gene namesi
Name:glnEUniRule annotation
Ordered Locus Names:SeHA_C3455
OrganismiSalmonella heidelberg (strain SL476)
Taxonomic identifieri454169 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001339141 – 947Glutamate-ammonia-ligase adenylyltransferaseAdd BLAST947

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni91 – 302GlnE 1Add BLAST212
Regioni610 – 831GlnE 2Add BLAST222

Sequence similaritiesi

Belongs to the GlnE family.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

HOGENOMiHOG000256491.
KOiK00982.
OMAiEFMVQYA.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4TI52-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPLSSPLSQ YWQTVVERLP EGFTETSLSA QAKSVLTFSD FALDSVIAHP
60 70 80 90 100
EWLAELESAS PQADEWRHYA GWLQEALAGV CDDASLMREL RFFRRRIMVR
110 120 130 140 150
IAWAQTLSLV DDETILQQLS HLAETLIVGA RDWLYAACCR EWGTPCNPQG
160 170 180 190 200
VPQPLLILGM GKLGGGELNF SSDIDLIFAW PEHGETRGGR RELDNAQFFT
210 220 230 240 250
RLGQRLIKAL DQPTMDGFVY RVDMRLRPFG DSGPLVLSFA ALEDYYQEQG
260 270 280 290 300
RDWERYAMVK ARLMGDNDDA WSRELRAMLR PFVFRRYIDF SVIQSLRNMK
310 320 330 340 350
GMIAREVRRR GLKDNIKLGA GGIREIEFIV QVFQLIRGGR EPSLQSRSLL
360 370 380 390 400
PTLDAIAALH LLPENDVAQL RVAYLFLRRL ENLLQSINDE QTQTLPADDL
410 420 430 440 450
NRARLAWGMK AENWPQLVGE LTDHMANVRR VFNELIGDDE ADTPQEEERS
460 470 480 490 500
EPWREVWQDA LQEDDSTPVL AHLADEDRRQ VLTLIADFRK ELDKRPIGPR
510 520 530 540 550
GRQVLDQLMP HLLADVCSRE DAVVTLSRIT PLLAGIVTRT TYLELLSEFP
560 570 580 590 600
GALKHLIMLC AASPMIASQL ARYPLLLDEL LDPGTLYQPT ATDAYRDELR
610 620 630 640 650
QYLLRVPEED EEQQLEALRQ FKQAQLLRIA AADIAGTLPV MKVSDHLTWL
660 670 680 690 700
AEAMIDAVVQ QAWTQMVARY GQPAHLDERQ GRGFAVVGYG KLGGWELGYS
710 720 730 740 750
SDLDLIFLHD CPMDVMTNGE REIDGRQFYL RLAQRIMHLF STRTSSGILY
760 770 780 790 800
EVDARLRPSG AAGMLVTSAD AFADYQQHEA WTWEHQALVR ARVVYGDPQL
810 820 830 840 850
TSQFDAVRRT IMTTARDGKT LQTEVREMRE KMRAHLGNKH RDRFDIKADE
860 870 880 890 900
GGITDIEFIA QYLVLRYAHE KPKLTRWSDN VRILELLAQN GIMDDHEAQA
910 920 930 940
LTVAYTTLRD ELHHLALQEL PGHVAQTCFS KERALVQASW RKWLVAV
Length:947
Mass (Da):108,009
Last modified:September 23, 2008 - v1
Checksum:i26BCF52C8393A356
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001120 Genomic DNA. Translation: ACF66089.1.
RefSeqiWP_000188295.1. NC_011083.1.

Genome annotation databases

EnsemblBacteriaiACF66089; ACF66089; SeHA_C3455.
KEGGiseh:SeHA_C3455.
PATRICi18514423. VBISalEnt43179_3290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001120 Genomic DNA. Translation: ACF66089.1.
RefSeqiWP_000188295.1. NC_011083.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACF66089; ACF66089; SeHA_C3455.
KEGGiseh:SeHA_C3455.
PATRICi18514423. VBISalEnt43179_3290.

Phylogenomic databases

HOGENOMiHOG000256491.
KOiK00982.
OMAiEFMVQYA.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLNE_SALHS
AccessioniPrimary (citable) accession number: B4TI52
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: November 2, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.