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Protein
Submitted name:

Uptake hydrogenase small subunit

Gene

SeHA_C1710

Organism
Salmonella heidelberg (strain SL476)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Cofactori

Protein has several cofactor binding sites:
  • [3Fe-4S] clusterUniRule annotationNote: Binds 1 [3Fe-4S] cluster.UniRule annotation
  • [4Fe-4S] clusterUniRule annotationNote: Binds 2 [4Fe-4S] clusters.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi62 – 621Iron-sulfur 1 (4Fe-4S)UniRule annotation
Metal bindingi65 – 651Iron-sulfur 1 (4Fe-4S)UniRule annotation
Metal bindingi160 – 1601Iron-sulfur 1 (4Fe-4S)UniRule annotation
Metal bindingi194 – 1941Iron-sulfur 1 (4Fe-4S)UniRule annotation
Metal bindingi232 – 2321Iron-sulfur 2 (4Fe-4S); via pros nitrogenUniRule annotation
Metal bindingi235 – 2351Iron-sulfur 2 (4Fe-4S)UniRule annotation
Metal bindingi260 – 2601Iron-sulfur 2 (4Fe-4S)UniRule annotation
Metal bindingi266 – 2661Iron-sulfur 2 (4Fe-4S)UniRule annotation
Metal bindingi275 – 2751Iron-sulfur 3 (3Fe-4S)UniRule annotation
Metal bindingi294 – 2941Iron-sulfur 3 (3Fe-4S)UniRule annotation
Metal bindingi297 – 2971Iron-sulfur 3 (3Fe-4S)UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

3Fe-4SUniRule annotation, 4Fe-4SUniRule annotation, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciSENT454169:GHYG-1698-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Uptake hydrogenase small subunitImported (EC:1.12.99.6Imported)
Gene namesi
Ordered Locus Names:SeHA_C1710Imported
OrganismiSalmonella heidelberg (strain SL476)Imported
Taxonomic identifieri454169 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001866 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB4THX1.

Structurei

3D structure databases

ProteinModelPortaliB4THX1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG1740.
HOGENOMiHOG000278822.
KOiK06282.
OMAiNPPLNQD.
OrthoDBiEOG6J74S9.

Family and domain databases

Gene3Di3.40.50.700. 1 hit.
4.10.480.10. 1 hit.
InterProiIPR027394. Cytochrome-c3_hydrogenase_C.
IPR006137. NADH_UbQ_OxRdtase-like_20kDa.
IPR001821. NiFe_hydrogenase_ssu.
IPR006311. TAT_signal.
IPR019546. TAT_signal_bac_arc.
[Graphical view]
PANTHERiPTHR30013. PTHR30013. 1 hit.
PfamiPF14720. NiFe_hyd_SSU_C. 1 hit.
PF01058. Oxidored_q6. 1 hit.
[Graphical view]
PIRSFiPIRSF000310. NiFe_hyd_ssu. 1 hit.
PRINTSiPR00614. NIHGNASESMLL.
TIGRFAMsiTIGR00391. hydA. 1 hit.
TIGR01409. TAT_signal_seq. 1 hit.
PROSITEiPS51318. TAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4THX1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTQDTFYQV MRRHGVTRRS FLKFCSLTAT SLGLSSSMIP QIAYALENKP
60 70 80 90 100
RTPVIWLHGL ECTCCTESFI RSAHPLAKDA ILSLISLDYD DTIMAAAGQQ
110 120 130 140 150
AEQALADVMR EYKGNYIVAV EGNAPLNEDG MFCILAGEPF LEKLKRVSAD
160 170 180 190 200
AKAIIAWGSC ASWGCVQAAR PNPTKATPVH KLITDKPIIK VPGCPPIPEV
210 220 230 240 250
MSAVITYMLA FDRIPPLDRL GRPKMFYGQR IHDKCYRRAH FDAGQFVEAW
260 270 280 290 300
DDEGARKGYC LYKMGCKGPT TYNACSTVRW NDGVSFPIQS GHGCLGCSED
310 320 330 340 350
GFWDYGSFYS RATGIPQTGI EATADKIGLG VAGVAGAAAI AHATVSAIKH
360
ARNKNNTSSE NAPEEKK
Length:367
Mass (Da):40,030
Last modified:September 23, 2008 - v1
Checksum:i3196635942431D56
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001120 Genomic DNA. Translation: ACF70397.1.
RefSeqiWP_001194448.1. NC_011083.1.
YP_002045577.1. NC_011083.1.

Genome annotation databases

EnsemblBacteriaiACF70397; ACF70397; SeHA_C1710.
KEGGiseh:SeHA_C1710.
PATRICi18511122. VBISalEnt43179_1668.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001120 Genomic DNA. Translation: ACF70397.1.
RefSeqiWP_001194448.1. NC_011083.1.
YP_002045577.1. NC_011083.1.

3D structure databases

ProteinModelPortaliB4THX1.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB4THX1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACF70397; ACF70397; SeHA_C1710.
KEGGiseh:SeHA_C1710.
PATRICi18511122. VBISalEnt43179_1668.

Phylogenomic databases

eggNOGiCOG1740.
HOGENOMiHOG000278822.
KOiK06282.
OMAiNPPLNQD.
OrthoDBiEOG6J74S9.

Enzyme and pathway databases

BioCyciSENT454169:GHYG-1698-MONOMER.

Family and domain databases

Gene3Di3.40.50.700. 1 hit.
4.10.480.10. 1 hit.
InterProiIPR027394. Cytochrome-c3_hydrogenase_C.
IPR006137. NADH_UbQ_OxRdtase-like_20kDa.
IPR001821. NiFe_hydrogenase_ssu.
IPR006311. TAT_signal.
IPR019546. TAT_signal_bac_arc.
[Graphical view]
PANTHERiPTHR30013. PTHR30013. 1 hit.
PfamiPF14720. NiFe_hyd_SSU_C. 1 hit.
PF01058. Oxidored_q6. 1 hit.
[Graphical view]
PIRSFiPIRSF000310. NiFe_hyd_ssu. 1 hit.
PRINTSiPR00614. NIHGNASESMLL.
TIGRFAMsiTIGR00391. hydA. 1 hit.
TIGR01409. TAT_signal_seq. 1 hit.
PROSITEiPS51318. TAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative genomics of 28 Salmonella enterica isolates: evidence for CRISPR-mediated adaptive sublineage evolution."
    Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G., Leclerc J.E., Ravel J., Cebula T.A.
    J. Bacteriol. 193:3556-3568(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SL476Imported.

Entry informationi

Entry nameiB4THX1_SALHS
AccessioniPrimary (citable) accession number: B4THX1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 22, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.