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B4TCP0

- B4TCP0_SALHS

UniProt

B4TCP0 - B4TCP0_SALHS

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Protein
Submitted name:

Aspartokinase/homoserine dehydrogenase II

Gene

metL

Organism
Salmonella heidelberg (strain SL476)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. aspartate kinase activity Source: UniProtKB-EC
  2. homoserine dehydrogenase activity Source: UniProtKB-EC
  3. NADP binding Source: InterPro

GO - Biological processi

  1. aspartate family amino acid biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, OxidoreductaseImported, Transferase

Enzyme and pathway databases

BioCyciSENT454169:GHYG-4407-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Aspartokinase/homoserine dehydrogenase IIImported (EC:1.1.1.3Imported, EC:2.7.2.4Imported)
Gene namesi
Name:metLImported
Ordered Locus Names:SeHA_C4435Imported
OrganismiSalmonella heidelberg (strain SL476)Imported
Taxonomic identifieri454169 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001866: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi454169.SeHA_C4435.

Structurei

3D structure databases

ProteinModelPortaliB4TCP0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0527.
HOGENOMiHOG000271594.
OMAiTLQYPEF.
OrthoDBiEOG6M0T34.

Family and domain databases

Gene3Di3.40.1160.10. 2 hits.
3.40.50.720. 1 hit.
InterProiIPR001048. Asp/Glu/Uridylate_kinase.
IPR005106. Asp/hSer_DH_NAD-bd.
IPR001341. Asp_kinase_dom.
IPR018042. Aspartate_kinase_CS.
IPR011147. Bifunc_aspartokin/hSer_DH.
IPR001342. HDH_cat.
IPR019811. HDH_CS.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00696. AA_kinase. 1 hit.
PF00742. Homoserine_dh. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000727. ThrA. 1 hit.
SUPFAMiSSF53633. SSF53633. 1 hit.
TIGRFAMsiTIGR00657. asp_kinases. 1 hit.
PROSITEiPS00324. ASPARTOKINASE. 1 hit.
PS01042. HOMOSER_DHGENASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4TCP0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSVIAQAGAK GRQLHKFGGS SLADVKCYLR VAGIMAEYSQ PDDMMVVSAA
60 70 80 90 100
GSTTNQLISW LKLSQTDRLS AHQVLQTLRR YQCDLISGLL PADVADDLTS
110 120 130 140 150
AFISDLERLA ALLDGGVTDA VYAEIVGHGE IWSARLMSAV LNQQGLDAAW
160 170 180 190 200
LDARAFLRAE RAAQPQVDEG LSYPLLQQLL AQHPGKRLVV TGFISRNHDG
210 220 230 240 250
ETVLLGRNGS DYSATQIGAL AGVSRVTIWS DVAGVYSADP RKVKDACLLP
260 270 280 290 300
LLRLDEASEL ARLAAPVLHA RTLQPVSGSD IDLQLRCSYT PDQGSTRIER
310 320 330 340 350
VLASGTGARI VTSHDDICLI EFQVPASQDF RLAHKELDHI LKRAQARPLA
360 370 380 390 400
VGVHRDRQLL QFCYTAEVAD SVLKLLDDVG LPGELRLRQG LALVAMVGAG
410 420 430 440 450
VTRNPLHCHR FWQQLKGQPV EFTWQSEEGI SLVAVLRTGP TESLIQGLHQ
460 470 480 490 500
SVFRAEKRIG LMLFGKGNIG SRWLELFARE QSTLSARTGF EFVLAGVVDS
510 520 530 540 550
RRSLLNYEGL DVSRALAFFD DEAVEQDEES LFLWMRAHPY DDLVVLDVTA
560 570 580 590 600
SEQLADQYLD FASHGFHVIS ANKLAGASAS DKYRQIHDAF EKTGRYWLYN
610 620 630 640 650
ATVGAGLPIN HTVRDLIDSG DTILSISGIF SGTLSWLFLQ FDGTVPFTDL
660 670 680 690 700
VDQAWQQGLT EPDPRVDLSG KDVMRKLVIL AREAGYDIEP DQVRVESLVP
710 720 730 740 750
AHCEEGSIDH FFENGDALNE QMVQRLEAAR ELGLVLRYVA RFDANGKARV
760 770 780 790 800
GVEAVRPEHP LAALLPCDNV FAIESRWYRD NPLVIRGPGA GRDVTAGAIQ
810
SDINRLAQLL
Length:810
Mass (Da):88,940
Last modified:September 23, 2008 - v1
Checksum:i7D0B849E904F71A4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001120 Genomic DNA. Translation: ACF68768.1.
RefSeqiYP_002048106.1. NC_011083.1.

Genome annotation databases

EnsemblBacteriaiACF68768; ACF68768; SeHA_C4435.
PATRICi18516317. VBISalEnt43179_4212.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001120 Genomic DNA. Translation: ACF68768.1 .
RefSeqi YP_002048106.1. NC_011083.1.

3D structure databases

ProteinModelPortali B4TCP0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 454169.SeHA_C4435.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACF68768 ; ACF68768 ; SeHA_C4435 .
PATRICi 18516317. VBISalEnt43179_4212.

Phylogenomic databases

eggNOGi COG0527.
HOGENOMi HOG000271594.
OMAi TLQYPEF.
OrthoDBi EOG6M0T34.

Enzyme and pathway databases

BioCyci SENT454169:GHYG-4407-MONOMER.

Family and domain databases

Gene3Di 3.40.1160.10. 2 hits.
3.40.50.720. 1 hit.
InterProi IPR001048. Asp/Glu/Uridylate_kinase.
IPR005106. Asp/hSer_DH_NAD-bd.
IPR001341. Asp_kinase_dom.
IPR018042. Aspartate_kinase_CS.
IPR011147. Bifunc_aspartokin/hSer_DH.
IPR001342. HDH_cat.
IPR019811. HDH_CS.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF00696. AA_kinase. 1 hit.
PF00742. Homoserine_dh. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000727. ThrA. 1 hit.
SUPFAMi SSF53633. SSF53633. 1 hit.
TIGRFAMsi TIGR00657. asp_kinases. 1 hit.
PROSITEi PS00324. ASPARTOKINASE. 1 hit.
PS01042. HOMOSER_DHGENASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genomics of 28 Salmonella enterica isolates: evidence for CRISPR-mediated adaptive sublineage evolution."
    Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G., Leclerc J.E., Ravel J., Cebula T.A.
    J. Bacteriol. 193:3556-3568(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SL476Imported.

Entry informationi

Entry nameiB4TCP0_SALHS
AccessioniPrimary (citable) accession number: B4TCP0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 1, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3