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Protein
Submitted name:

Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component

Gene

sucA

Organism
Salmonella heidelberg (strain SL476)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Enzyme and pathway databases

BioCyciSENT454169:GHYG-850-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Oxoglutarate dehydrogenase (Succinyl-transferring), E1 componentImported (EC:1.2.4.2Imported)
Gene namesi
Name:sucAImported
Ordered Locus Names:SeHA_C0859Imported
OrganismiSalmonella heidelberg (strain SL476)Imported
Taxonomic identifieri454169 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001866 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi454169.SeHA_C0859.

Structurei

3D structure databases

ProteinModelPortaliB4TBD5.
SMRiB4TBD5. Positions 84-933.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259588.
OMAiQNQGAWF.
OrthoDBiEOG6V1M1F.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

B4TBD5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQNSALKAWL DSSYLSGSNQ SWIEQLYEDF LTDPDSVDAN WRLTFQQLPG
60 70 80 90 100
TGVKPDQLHS KTREYFRRQA LAGSRHSSTI SDPDTNVKQV KVLQLINAYR
110 120 130 140 150
FRGHQHANLD PLGLWKQERV ADLDPSFHDL TEADFQETFN VGSFASGKET
160 170 180 190 200
MKLGELLDAL KQTYCGPIGA EYMHITSTEE KRWIQQRIES GRAAFSADEK
210 220 230 240 250
KRFLNELTAA EGLERYLGAK FPGAKRFSLE GGDALIPMLK EMVRHAGNSG
260 270 280 290 300
TREVVLGMAH RGRLNVLINV LGKKPQDLFD EFAGKHKEHL GTGDVKYHMG
310 320 330 340 350
FSSDIETEGG LVHLALAFNP SHLEIVSPVV MGSVRARLDR LDEPSSNKVL
360 370 380 390 400
PITIHGDAAV TGQGVVQETL NMSKARGYEV GGTVRIVINN QVGFTTSNPL
410 420 430 440 450
DARSTPYCTD IGKMVQAPIF HVNADDPEAV AFVTRLALDF RNTFKRDVFI
460 470 480 490 500
DLVCYRRHGH NEADEPSATQ PLMYQKIKKH PTPRKIYADK LEADKVATLE
510 520 530 540 550
DATEMVNLYR DALDAGECVV KEWRPMNMHS FTWSPYLNHE WDEAYPNKVE
560 570 580 590 600
MKRLQELAKR ISTVPEAIEM QSRVAKIYGD RQAMAAGEKL FDWGGAENLA
610 620 630 640 650
YATLVDEGIP VRLSGEDSGR GTFFHRHAVI HNQTNGSTYT PLQHIHSGQG
660 670 680 690 700
QFKVWDSVLS EEAVLAFEYG YATAEPRTLT IWEAQFGDFA NGAQVVIDQF
710 720 730 740 750
ISSGEQKWGR MCGLVMLLPH GYEGQGPEHS SARLERYLQL CAEQNMQVCV
760 770 780 790 800
PSTPAQVYHM LRRQALRGMR RPLVVMSPKS LLRHPLAVST LDELANGSFQ
810 820 830 840 850
PAIGEIDELD PKAVKRVVMC SGKVYYDLLE QRRKNDQKDV AIVRIEQLYP
860 870 880 890 900
FPHKAVQEAL QPYAHVHDFV WCQEEPLNQG AWYCSQHHFR EVIPFGAALR
910 920 930
YAGRPASASP AVGYMSVHQK QQQDLVNDAL NVD
Length:933
Mass (Da):104,836
Last modified:September 22, 2008 - v1
Checksum:i0445CE6DE4DBA5F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001120 Genomic DNA. Translation: ACF68604.1.
RefSeqiYP_002044766.1. NC_011083.1.

Genome annotation databases

EnsemblBacteriaiACF68604; ACF68604; SeHA_C0859.
PATRICi18509496. VBISalEnt43179_0865.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001120 Genomic DNA. Translation: ACF68604.1.
RefSeqiYP_002044766.1. NC_011083.1.

3D structure databases

ProteinModelPortaliB4TBD5.
SMRiB4TBD5. Positions 84-933.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi454169.SeHA_C0859.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACF68604; ACF68604; SeHA_C0859.
PATRICi18509496. VBISalEnt43179_0865.

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259588.
OMAiQNQGAWF.
OrthoDBiEOG6V1M1F.

Enzyme and pathway databases

BioCyciSENT454169:GHYG-850-MONOMER.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Comparative genomics of 28 Salmonella enterica isolates: evidence for CRISPR-mediated adaptive sublineage evolution."
    Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G., Leclerc J.E., Ravel J., Cebula T.A.
    J. Bacteriol. 193:3556-3568(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SL476Imported.

Entry informationi

Entry nameiB4TBD5_SALHS
AccessioniPrimary (citable) accession number: B4TBD5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 22, 2008
Last sequence update: September 22, 2008
Last modified: January 6, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.