Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Aminomethyltransferase

Gene

gcvT

Organism
Salmonella newport (strain SL254)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine.UniRule annotation

Catalytic activityi

[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Enzyme and pathway databases

BioCyciSENT423368:GHJB-3262-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
AminomethyltransferaseUniRule annotation (EC:2.1.2.10UniRule annotation)
Alternative name(s):
Glycine cleavage system T proteinUniRule annotation
Gene namesi
Name:gcvTUniRule annotation
Ordered Locus Names:SNSL254_A3290
OrganismiSalmonella newport (strain SL254)
Taxonomic identifieri423368 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000008824 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 364364AminomethyltransferasePRO_1000114114Add
BLAST

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB4T550.
SMRiB4T550. Positions 4-364.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvT family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000239381.
KOiK00605.
OMAiLGWLVHL.

Family and domain databases

Gene3Di2.40.30.110. 1 hit.
3.30.1360.120. 2 hits.
HAMAPiMF_00259. GcvT. 1 hit.
InterProiIPR006223. GCS_T.
IPR022903. GCS_T_bac.
IPR028896. GCST/DmdA.
IPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR029043. GcvT/YgfZ_C.
IPR027266. TrmE/GcvT_dom1.
[Graphical view]
PANTHERiPTHR13847:SF5. PTHR13847:SF5. 1 hit.
PfamiPF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view]
PIRSFiPIRSF006487. GcvT. 1 hit.
SUPFAMiSSF101790. SSF101790. 1 hit.
TIGRFAMsiTIGR00528. gcvT. 1 hit.

Sequencei

Sequence statusi: Complete.

B4T550-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQQTPLYEQ HTLCGARMVD FHGWMMPLHY GSQLDEHHAV RTDAGMFDVS
60 70 80 90 100
HMTIVDLHGS RTREFLRYLL ANDVAKLTKT GKALYSGMLN ASGGVIDDLI
110 120 130 140 150
VYYFTEDFFR LVVNSATREK DLSWITQHAE PYAIDITVRD DLSLIAVQGP
160 170 180 190 200
NAQEKAATLF TDEQRHAVEG MKPFFGVQAG DLFIATTGYT GEAGYEIAMP
210 220 230 240 250
NEKAADFWRA LVEAGVKPCG LGARDTLRLE AGMNLYGQEM DEGISPLAAN
260 270 280 290 300
MGWTIAWEPA DRDFIGREAL EMQREKGHEQ LVGLVMTEKG VLRNELPVRF
310 320 330 340 350
TDAQGNQQEG IITSGTFSPT LGYSIALARV PAGIGETAIV QIRNREMPVK
360
VTKPVFVRNG KAVA
Length:364
Mass (Da):40,218
Last modified:September 23, 2008 - v1
Checksum:i461E1B330AF92123
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001113 Genomic DNA. Translation: ACF62354.1.
RefSeqiWP_000068733.1. NZ_CCMR01000001.1.

Genome annotation databases

EnsemblBacteriaiACF62354; ACF62354; SNSL254_A3290.
KEGGisee:SNSL254_A3290.
PATRICi18524938. VBISalEnt114557_3336.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001113 Genomic DNA. Translation: ACF62354.1.
RefSeqiWP_000068733.1. NZ_CCMR01000001.1.

3D structure databases

ProteinModelPortaliB4T550.
SMRiB4T550. Positions 4-364.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACF62354; ACF62354; SNSL254_A3290.
KEGGisee:SNSL254_A3290.
PATRICi18524938. VBISalEnt114557_3336.

Phylogenomic databases

HOGENOMiHOG000239381.
KOiK00605.
OMAiLGWLVHL.

Enzyme and pathway databases

BioCyciSENT423368:GHJB-3262-MONOMER.

Family and domain databases

Gene3Di2.40.30.110. 1 hit.
3.30.1360.120. 2 hits.
HAMAPiMF_00259. GcvT. 1 hit.
InterProiIPR006223. GCS_T.
IPR022903. GCS_T_bac.
IPR028896. GCST/DmdA.
IPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR029043. GcvT/YgfZ_C.
IPR027266. TrmE/GcvT_dom1.
[Graphical view]
PANTHERiPTHR13847:SF5. PTHR13847:SF5. 1 hit.
PfamiPF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view]
PIRSFiPIRSF006487. GcvT. 1 hit.
SUPFAMiSSF101790. SSF101790. 1 hit.
TIGRFAMsiTIGR00528. gcvT. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGCST_SALNS
AccessioniPrimary (citable) accession number: B4T550
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 23, 2008
Last modified: September 7, 2016
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.