B4T4F9 (RSMC_SALNS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase C
EC=2.1.1.172

Alternative name(s):
16S rRNA m2G1207 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RsmC

Gene names

Name:	rsmC
Ordered Locus Names:	SNSL254_A4912

Organism

Salmonella newport (strain SL254) [Complete proteome] [HAMAP]

Taxonomic identifier

423368 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella newport

Protein attributes

Sequence length	342 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1207 of 16S rRNA in the 30S particle By similarity. HAMAP MF_01862
Catalytic activity	S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1207) in 16S rRNA. HAMAP MF_01862
Subunit structure	Monomer By similarity. HAMAP MF_01862
Subcellular location	Cytoplasm Potential HAMAP MF_01862.
Sequence similarities	Belongs to the methyltransferase superfamily. RsmC family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nucleic acid binding Inferred from electronic annotation. Source: InterPro rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 342	342	Ribosomal RNA small subunit methyltransferase C HAMAP MF_01862		PRO_0000369758

Sequences

	Sequence		Length	Mass (Da)
	B4T4F9 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 4D8CC4533395381D	FASTA	342	37,649
	10 20 30 40 50 60 MSAFTPASEV LLRHSDDFEQ SRILFAGDLQ DDLPARFECA ASRAHTQQFH HWQVLSRQMG 70 80 90 100 110 120 DNVRFSLVAQ ASDVADCDTL IYYWPKNKPE AQFQLMNILS LMPSGSDVFV VGENRSGVRS 130 140 150 160 170 180 AEQMLADYAP LNKVDSARRC GLYHGRLEKQ PQFSLESWWA EYNIDGLTIK TLPGVFSRDG 190 200 210 220 230 240 LDVGSQLLLS TLTPHTKGKV LDVGCGAGVL SAALASHSPK VRLTLCDVSA PAVEASRATL 250 260 270 280 290 300 AANGLEGEVF ASNIFSEVKG RFDMIISNPP FHDGMQTSLD AAQTLIRGAV RHLNSGGELR 310 320 330 340 IVANAFLPYP KILDETFGFH EVIAQTGRFK VYRTVMTRQA KK

References

[1]	"Complete genome of Salmonella newport strain SL254." Ravel J., Fricke W.F., White D., McDermott P., Mammel M., Rosovitz M., Leclerc J., Cebula T., Sebastian Y. Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SL254.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001113 Genomic DNA. Translation: ACF63430.1.
RefSeq	YP_002043797.1. NC_011080.1.
3D structure databases
ProteinModelPortal	B4T4F9.
ModBase	Search...
Protein-protein interaction databases
STRING	B4T4F9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6486976.
GenomeReviews	Gene locus SNSL254_A4912 in contig CP001113_GR.
KEGG	see:SNSL254_A4912.
PATRIC	18528114. VBISalEnt114557_4875.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG296757.
OMA	TGKFKVY.
ProtClustDB	PRK09489.
Family and domain databases
HAMAP	MF_01862. 16SrRNA_methyltr_C. [Tree]
InterPro	IPR002052. DNA_methylase_N6_adenine_CS. IPR013675. Mtase_sm_N. IPR023543. rRNA_ssu_MeTfrase_C. IPR007848. Small_mtfrase. [Graphical view]
KO	K00564.
Pfam	PF05175. MTS. 1 hit. PF08468. MTS_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RSMC_SALNS

Accession

Primary (citable) accession number: B4T4F9

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	September 23, 2008
Last modified:	January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program