Skip Header

Contribute Send feedback
Read comments (?) or add your own

B4SWS3 (PHNW_SALNS) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
2-aminoethylphosphonate--pyruvate transaminase
EC=2.6.1.37
Alternative name(s):
2-aminoethylphosphonate aminotransferase
AEP transaminase
Short name=AEPT
Gene names
Name:phnW
Ordered Locus Names:SNSL254_A0478
OrganismSalmonella newport (strain SL254) [Complete proteome] [HAMAP]
Taxonomic identifier423368 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella ›

Protein attributes

Sequence length367 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in phosphonate degradation By similarity.

Catalytic activity

(2-aminoethyl)phosphonate + pyruvate = 2-phosphonoacetaldehyde + L-alanine. HAMAP-Rule MF_01376

Cofactor

Pyridoxal phosphate By similarity.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3673672-aminoethylphosphonate--pyruvate transaminase HAMAP-Rule MF_01376
PRO_1000144859

Amino acid modifications

Modified residue1941N6-(pyridoxal phosphate)lysine Potential

Sequences

Sequence LengthMass (Da)Tools
B4SWS3 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: EA0696BF9567567F

FASTA36740,337
        10         20         30         40         50         60 
MTSRNYLLLT PGPLTTSRTV KEAMLFDSCT WDDDYNIGVV EQIRQQLTEL ATASEGYTSV 

        70         80         90        100        110        120 
LLQGSGSYAV EAVLGSALGP QDKVLIVSNG AYGARMVEMA GLMGIAHHAY DCGEVARPDV 

       130        140        150        160        170        180 
QAIDAILNAD PTISHIAMVH SETTTGMLNP IDEVGALAHR YGKTYIVDAM SSFGGIPMDI 

       190        200        210        220        230        240 
AALHIDYLIS SANKCIQGVP GFAFVIAREQ KLAACKGHSR SLSLDLYAQW RCMEDNHGKW 

       250        260        270        280        290        300 
RFTSPTHTVL AFAQALKELA KEGGVAARHQ RYQQNQRSLV AGMRALGFNT LLDDELHSPI 

       310        320        330        340        350        360 
ITAFYSPEDP QYRFSEFYRR LKEQGFVIYP GKVSQSDCFR IGNIGEVYAA DITALLTAIR 


TAMYWMK

« Hide

References

[1]"Complete genome of Salmonella newport strain SL254."
Ravel J., Fricke W.F., White D., McDermott P., Mammel M., Rosovitz M., Leclerc J., Cebula T., Sebastian Y.
Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SL254.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001113 Genomic DNA. Translation: ACF64097.1.
RefSeqYP_002039673.1. NC_011080.1.

3D structure databases

ProteinModelPortalB4SWS3.
ModBaseSearch...

Protein-protein interaction databases

STRING423368.SNSL254_A0478.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACF64097; ACF64097; SNSL254_A0478.
GeneID6485698.
KEGGsee:SNSL254_A0478.
PATRIC18519390. VBISalEnt114557_0614.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0075.
HOGENOMHOG000171816.
KOK03430.
OMAHSLAMDL.
ProtClustDBPRK13479.

Enzyme and pathway databases

BioCycSENT423368:GHJB-3107-MONOMER.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
HAMAPMF_01376. PhnW_aminotrans_5.
InterProIPR000192. Aminotrans_V/Cys_dSase.
IPR012703. NH2EtPonate_pyrv_transaminase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR024169. SP_NH2Trfase/AEP_transaminase.
[Graphical view]
PANTHERPTHR21152:SF6. PTHR21152:SF6. 1 hit.
PfamPF00266. Aminotran_5. 1 hit.
[Graphical view]
PIRSFPIRSF000524. SPT. 1 hit.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR03301. PhnW-AepZ. 1 hit.
TIGR02326. transamin_PhnW. 1 hit.
PROSITEPS00595. AA_TRANSFER_CLASS_5. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePHNW_SALNS
AccessionPrimary (citable) accession number: B4SWS3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: May 1, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents