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B4STS7

- TRMB_STRM5

UniProt

B4STS7 - TRMB_STRM5

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Protein
tRNA (guanine-N(7)-)-methyltransferase
Gene
trmB, Smal_3191
Organism
Stenotrophomonas maltophilia (strain R551-3)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei75 – 751S-adenosyl-L-methionine By similarity
Binding sitei100 – 1001S-adenosyl-L-methionine By similarity
Binding sitei127 – 1271S-adenosyl-L-methionine By similarity
Active sitei150 – 1501 By similarity
Binding sitei150 – 1501S-adenosyl-L-methionine By similarity
Binding sitei154 – 1541Substrate By similarity
Binding sitei186 – 1861Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciSMAL391008:GH1H-3264-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:Smal_3191
OrganismiStenotrophomonas maltophilia (strain R551-3)
Taxonomic identifieri391008 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeStenotrophomonasStenotrophomonas maltophilia group
ProteomesiUP000001867: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 244244tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation
PRO_1000136367Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi391008.Smal_3191.

Structurei

3D structure databases

ProteinModelPortaliB4STS7.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni156 – 1616Interaction with RNA Reviewed prediction
Regioni223 – 2264Substrate binding Reviewed prediction

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000073968.
KOiK03439.
OMAiHSTLEMA.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4STS7-1 [UniParc]FASTAAdd to Basket

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MTNPFDSAGS KAPPKPFTVS EGRREVRSFV LRQGRFTPAQ QRAFDERWPR    50
FGIDYNGQPR DLDATFGRPA HKVLEIGFGN GAAMRFAAQH DPSRDYIGIE 100
VHAPGVGRLL NALADDNADH VRLYHHDAVE VLQNEIADGA LDEVRIYFPD 150
PWHKKRHNKR RLLQPAFAEL IVRKLRPGGR LHCATDWEDY AEQMWDVLDA 200
TAGLVNRAGP RGSVPRPDWR PQTHFETRGQ KLGHGVWDLL YDRT 244
Length:244
Mass (Da):27,802
Last modified:September 23, 2008 - v1
Checksum:i92533248C13BCB8E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001111 Genomic DNA. Translation: ACF52890.1.
RefSeqiWP_006387461.1. NC_011071.1.
YP_002029573.1. NC_011071.1.

Genome annotation databases

EnsemblBacteriaiACF52890; ACF52890; Smal_3191.
GeneIDi6476163.
KEGGismt:Smal_3191.
PATRICi23711366. VBISteMal40512_3215.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001111 Genomic DNA. Translation: ACF52890.1 .
RefSeqi WP_006387461.1. NC_011071.1.
YP_002029573.1. NC_011071.1.

3D structure databases

ProteinModelPortali B4STS7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 391008.Smal_3191.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACF52890 ; ACF52890 ; Smal_3191 .
GeneIDi 6476163.
KEGGi smt:Smal_3191.
PATRICi 23711366. VBISteMal40512_3215.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000073968.
KOi K03439.
OMAi HSTLEMA.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci SMAL391008:GH1H-3264-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: R551-3.

Entry informationi

Entry nameiTRMB_STRM5
AccessioniPrimary (citable) accession number: B4STS7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: September 3, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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