SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B4SRU3

- UPPP_STRM5

UniProt

B4SRU3 - UPPP_STRM5

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Undecaprenyl-diphosphatase

Gene
uppP, Smal_0108
Organism
Stenotrophomonas maltophilia (strain R551-3)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity.UniRule annotation

Catalytic activityi

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate.UniRule annotation

GO - Molecular functioni

  1. undecaprenyl-diphosphatase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dephosphorylation Source: InterPro
  2. peptidoglycan biosynthetic process Source: UniProtKB-KW
  3. regulation of cell shape Source: UniProtKB-KW
  4. response to antibiotic Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Antibiotic resistance, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciSMAL391008:GH1H-108-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Undecaprenyl-diphosphatase (EC:3.6.1.27)
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene namesi
Name:uppP
Ordered Locus Names:Smal_0108
OrganismiStenotrophomonas maltophilia (strain R551-3)
Taxonomic identifieri391008 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeStenotrophomonasStenotrophomonas maltophilia group
ProteomesiUP000001867: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei38 – 5821Helical; Reviewed predictionAdd
BLAST
Transmembranei75 – 9521Helical; Reviewed predictionAdd
BLAST
Transmembranei106 – 12621Helical; Reviewed predictionAdd
BLAST
Transmembranei136 – 15621Helical; Reviewed predictionAdd
BLAST
Transmembranei181 – 20121Helical; Reviewed predictionAdd
BLAST
Transmembranei217 – 23721Helical; Reviewed predictionAdd
BLAST
Transmembranei242 – 26221Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 264264Undecaprenyl-diphosphataseUniRule annotationPRO_1000197408Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi391008.Smal_0108.

Family & Domainsi

Sequence similaritiesi

Belongs to the UppP family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1968.
HOGENOMiHOG000218356.
KOiK06153.
OMAiWDKIMST.
OrthoDBiEOG6QP13M.

Family and domain databases

HAMAPiMF_01006. Undec_diphosphatase.
InterProiIPR003824. UppP.
[Graphical view]
PfamiPF02673. BacA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4SRU3-1 [UniParc]FASTAAdd to Basket

« Hide

MSDLLSALLL GILEGLTEFL PISSTGHLLI AQHWLGARSD FFNIVIQAGA    50
IVAVVLVFRQ RLLQLATGFG QRENREYVFK LGAAFLVTAV VGLVVRKAGW 100
SLPETVSPVA WALIIGGIWM LLVEAYTARL PDRDQVTWTV AIGVGLAQVV 150
AGVFPGTSRS ASAIFLAMLL GLSRRAAAAE FVFLVGIPTM FAASAYTFLE 200
MAKAGQLGSE NWTEVGVAFL AAAVTGFVVV KWLMGYIKSH KFTAFALYRI 250
ALGAALLLWL PSGS 264
Length:264
Mass (Da):28,246
Last modified:September 23, 2008 - v1
Checksum:iA9D3F1F178508267
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001111 Genomic DNA. Translation: ACF49813.1.
RefSeqiWP_012509682.1. NC_011071.1.
YP_002026496.1. NC_011071.1.

Genome annotation databases

EnsemblBacteriaiACF49813; ACF49813; Smal_0108.
GeneIDi6477657.
KEGGismt:Smal_0108.
PATRICi23705010. VBISteMal40512_0109.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001111 Genomic DNA. Translation: ACF49813.1 .
RefSeqi WP_012509682.1. NC_011071.1.
YP_002026496.1. NC_011071.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 391008.Smal_0108.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACF49813 ; ACF49813 ; Smal_0108 .
GeneIDi 6477657.
KEGGi smt:Smal_0108.
PATRICi 23705010. VBISteMal40512_0109.

Phylogenomic databases

eggNOGi COG1968.
HOGENOMi HOG000218356.
KOi K06153.
OMAi WDKIMST.
OrthoDBi EOG6QP13M.

Enzyme and pathway databases

BioCyci SMAL391008:GH1H-108-MONOMER.

Family and domain databases

HAMAPi MF_01006. Undec_diphosphatase.
InterProi IPR003824. UppP.
[Graphical view ]
Pfami PF02673. BacA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: R551-3.

Entry informationi

Entry nameiUPPP_STRM5
AccessioniPrimary (citable) accession number: B4SRU3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: September 3, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi