Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B4SHI1

- CYOE_STRM5

UniProt

B4SHI1 - CYOE_STRM5

Protein

Protoheme IX farnesyltransferase

Gene

cyoE

Organism
Stenotrophomonas maltophilia (strain R551-3)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. protoheme IX farnesyltransferase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. heme O biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Heme biosynthesis

    Enzyme and pathway databases

    BioCyciSMAL391008:GH1H-331-MONOMER.
    UniPathwayiUPA00834; UER00712.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protoheme IX farnesyltransferaseUniRule annotation (EC:2.5.1.-UniRule annotation)
    Alternative name(s):
    Heme B farnesyltransferaseUniRule annotation
    Heme O synthaseUniRule annotation
    Gene namesi
    Name:cyoEUniRule annotation
    Ordered Locus Names:Smal_0319
    OrganismiStenotrophomonas maltophilia (strain R551-3)
    Taxonomic identifieri391008 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeStenotrophomonasStenotrophomonas maltophilia group
    ProteomesiUP000001867: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 297297Protoheme IX farnesyltransferasePRO_1000096927Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi391008.Smal_0319.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei16 – 3621HelicalUniRule annotationAdd
    BLAST
    Transmembranei45 – 6521HelicalUniRule annotationAdd
    BLAST
    Transmembranei93 – 11321HelicalUniRule annotationAdd
    BLAST
    Transmembranei114 – 13421HelicalUniRule annotationAdd
    BLAST
    Transmembranei141 – 16121HelicalUniRule annotationAdd
    BLAST
    Transmembranei172 – 19221HelicalUniRule annotationAdd
    BLAST
    Transmembranei223 – 24321HelicalUniRule annotationAdd
    BLAST
    Transmembranei244 – 26421HelicalUniRule annotationAdd
    BLAST
    Transmembranei277 – 29721HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0109.
    HOGENOMiHOG000237291.
    KOiK02301.
    OMAiIMERTRH.
    OrthoDBiEOG6DVJQB.

    Family and domain databases

    HAMAPiMF_00154. CyoE_CtaB.
    InterProiIPR006369. Protohaem_IX_farnesylTrfase.
    IPR000537. UbiA_prenyltransferase.
    [Graphical view]
    PfamiPF01040. UbiA. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01473. cyoE_ctaB. 1 hit.
    PROSITEiPS00943. UBIA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4SHI1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFSNYRQYWD LTKPKVVALI VFTALVGMVL AIPGVPSWEQ VRAGVLGFLG    50
    IWLAASAAAA INQLLDAHID AQMARTSWRP LVVGKVKPWQ VLVFASVLIV 100
    LSMVILVLWV NLITAVLTFA SLIGYAVIYT VYLKRATSQN IVIGGLAGAM 150
    PPMLGWAAVT GMQGSSDWAY SSLLVLIIFI WTPPHFWALA IFRREDYAKA 200
    EIPMLPVTHG VVHTRKQIMV YSVVLALVCL LPYLVGMSGA FYLGGAIVLN 250
    AVFLWYAWRM LDPPDELFSM KMFYYSIVYL MALFAFLLVD HWILPWL 297
    Length:297
    Mass (Da):33,163
    Last modified:September 23, 2008 - v1
    Checksum:i00C3B34D22A1F334
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001111 Genomic DNA. Translation: ACF50024.1.
    RefSeqiYP_002026707.1. NC_011071.1.

    Genome annotation databases

    EnsemblBacteriaiACF50024; ACF50024; Smal_0319.
    GeneIDi6478115.
    KEGGismt:Smal_0319.
    PATRICi23705456. VBISteMal40512_0320.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001111 Genomic DNA. Translation: ACF50024.1 .
    RefSeqi YP_002026707.1. NC_011071.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 391008.Smal_0319.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACF50024 ; ACF50024 ; Smal_0319 .
    GeneIDi 6478115.
    KEGGi smt:Smal_0319.
    PATRICi 23705456. VBISteMal40512_0320.

    Phylogenomic databases

    eggNOGi COG0109.
    HOGENOMi HOG000237291.
    KOi K02301.
    OMAi IMERTRH.
    OrthoDBi EOG6DVJQB.

    Enzyme and pathway databases

    UniPathwayi UPA00834 ; UER00712 .
    BioCyci SMAL391008:GH1H-331-MONOMER.

    Family and domain databases

    HAMAPi MF_00154. CyoE_CtaB.
    InterProi IPR006369. Protohaem_IX_farnesylTrfase.
    IPR000537. UbiA_prenyltransferase.
    [Graphical view ]
    Pfami PF01040. UbiA. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01473. cyoE_ctaB. 1 hit.
    PROSITEi PS00943. UBIA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: R551-3.

    Entry informationi

    Entry nameiCYOE_STRM5
    AccessioniPrimary (citable) accession number: B4SHI1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.UniRule annotation

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3