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B4SE25 (B4SE25_PELPB) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydroorotate dehydrogenase HAMAP MF_00224
Short name=DHOD HAMAP MF_00224
Short name=DHODase HAMAP MF_00224
Short name=DHOdehase HAMAP MF_00224
EC=1.3.-.- HAMAP MF_00224
Gene names
Name:pyrD HAMAP MF_00224
Ordered Locus Names:Ppha_0721
OrganismPelodictyon phaeoclathratiforme (strain DSM 5477 / BU-1) [Complete proteome] [HAMAP]
Taxonomic identifier324925 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Pelodictyon

Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of dihydroorotate to orotate By similarity. HAMAP MF_00224

Catalytic activity

(S)-dihydroorotate + acceptor = orotate + reduced acceptor. HAMAP MF_00224

Cofactor

Binds 1 FMN per subunit By similarity. HAMAP MF_00224 SAAS SAAS012135

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway. HAMAP MF_00224

Subcellular location

Cytoplasm By similarity HAMAP MF_00224.

Sequence similarities

Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. HAMAP MF_00224

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1331Nucleophile By similarity PIRSR PIRSR000164-1

Sequences

Sequence LengthMass (Da)Tools
B4SE25 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: D1570EE9BB78F8AF

FASTA30732,754
        10         20         30         40         50         60 
MSQHQTALSL GRGLDLQSPV LLASGTVSYG EELSQLCDLS KIGGIVTKAI SLEPRMGNPP 

        70         80         90        100        110        120 
QRIAETPSGM INAIGLANVG VERFITEKVP FLRQLKTAVI VNIAGRSIDD YCEVVSRLDE 

       130        140        150        160        170        180 
VDGLNGYEIN LSCPNVKGEC MIMGVSRDAT FEIVSELRRI TNRHLMIKLT PNVTSISSIA 

       190        200        210        220        230        240 
LAAEEAGADS LSLINTVVGM AINSKTRRPL LKNITGGLSG PAIKPIALAK VWEVYNAVTI 

       250        260        270        280        290        300 
PLVGMGGIAS FEDAMEFLLA GSRAIQIGTM NFVYPDIGEK IATAIEQYFS TPGAPSLREY 


SGSLLVD

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References

[1]"Complete sequence of Pelodictyon phaeoclathratiforme BU-1."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Liu Z., Li T., Zhao F. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 5477 / BU-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001110 Genomic DNA. Translation: ACF43016.1.
RefSeqYP_002017633.1. NC_011060.1.

3D structure databases

ProteinModelPortalB4SE25.
ModBaseSearch...

Protein-protein interaction databases

STRINGB4SE25.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6461461.
GenomeReviewsGene locus Ppha_0721 in contig CP001110_GR.
KEGGpph:Ppha_0721.
PATRIC22901878. VBIPelPha134556_0731.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG472415.
OMAVALRMVW.
ProtClustDBCLSK637846.

Family and domain databases

HAMAPMF_00224. DHO_dh_type1.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR005720. Dihydroorotate_DH.
IPR024920. Dihydroorotate_DH_1.
IPR012135. Dihydroorotate_DH_1_2.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK00226.
PfamPF01180. DHO_dh. 1 hit.
[Graphical view]
PIRSFPIRSF000164. DHO_oxidase. 1 hit.
TIGRFAMsTIGR01037. PyrD_sub1_fam. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB4SE25_PELPB
AccessionPrimary (citable) accession number: B4SE25
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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