Skip Header

Contribute Send feedback
Read comments (?) or add your own

B4SDS6 (B4SDS6_PELPB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Non-canonical purine NTP pyrophosphatase HAMAP MF_01405
EC=3.6.1.19 HAMAP MF_01405
Alternative name(s):
Non-standard purine NTP pyrophosphatase HAMAP MF_01405
Nucleoside-triphosphate diphosphatase HAMAP MF_01405
Nucleoside-triphosphate pyrophosphatase HAMAP MF_01405
Gene names
Ordered Locus Names:Ppha_2249
OrganismPelodictyon phaeoclathratiforme (strain DSM 5477 / BU-1) [Complete proteome] [HAMAP]
Taxonomic identifier324925 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Pelodictyon

Protein attributes

Sequence length234 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions By similarity. HAMAP MF_01405

Catalytic activity

A nucleoside triphosphate + H2O = a nucleotide + diphosphate. HAMAP MF_01405 SAAS SAAS020922

Cofactor

Binds 1 divalent metal cation ion per subunit; can use either magnesium or manganese By similarity. HAMAP MF_01405 SAAS SAAS020922

Subunit structure

Homodimer By similarity. HAMAP MF_01405 SAAS SAAS020922

Sequence similarities

Belongs to the HAM1 NTPase family. HAMAP MF_01405 RuleBase RU003781

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region15 – 206Substrate binding By similarity HAMAP MF_01405
Region84 – 852Substrate binding By similarity HAMAP MF_01405

Sites

Metal binding501Magnesium or manganese By similarity HAMAP MF_01405
Metal binding841Magnesium or manganese By similarity HAMAP MF_01405
Binding site1791Substrate By similarity HAMAP MF_01405
Binding site1991Substrate By similarity HAMAP MF_01405
Binding site2051Substrate By similarity HAMAP MF_01405

Sequences

Sequence LengthMass (Da)Tools
B4SDS6 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: CCE4F7328BAD7D37

FASTA23425,609
        10         20         30         40         50         60 
MPATADKEIT IVLATANRDK VKELRPLLET ISPLFTVRTL HELGVDVEIE ETEETLEGNA 

        70         80         90        100        110        120 
LLKARAIFAI LSERFPFMIA LADDTGLEVD GLDGAPGVYS ARFAPVPDGQ SPTYKDNVAH 

       130        140        150        160        170        180 
LLHCMKGIAN REARFRTVIA LKGALPSAEG CFRFEHTAEG VVPGSITLEE QGVEGFGYDP 

       190        200        210        220        230 
LFLVHNTGKT YAEMSTTEKN RLSHRALAVQ HAVNYLKNIL QQKSVLPTDT TTHP

« Hide

References

[1]"Complete sequence of Pelodictyon phaeoclathratiforme BU-1."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Liu Z., Li T., Zhao F. expand/collapse author list , Overmann J., Bryant D.A., Richardson P.
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 5477 / BU-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001110 Genomic DNA. Translation: ACF44444.1.
RefSeqYP_002019061.1. NC_011060.1.

3D structure databases

ProteinModelPortalB4SDS6.
ModBaseSearch...

Protein-protein interaction databases

STRINGB4SDS6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6461187.
GenomeReviewsGene locus Ppha_2249 in contig CP001110_GR.
KEGGpph:Ppha_2249.
PATRIC22905265. VBIPelPha134556_2398.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG697237.
OMAGVYTADW.
ProtClustDBPRK14826.

Family and domain databases

HAMAPMF_01405. Non_canon_purine_NTPase.
[Tree]
InterProIPR002637. Ham1p-like.
IPR020922. Nucleoside-triphosphatase.
[Graphical view]
KOK02428.
PANTHERPTHR11067. Ham1p_like. 1 hit.
PfamPF01725. Ham1p_like. 1 hit.
[Graphical view]
TIGRFAMsTIGR00042. TIGR00042. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB4SDS6_PELPB
AccessionPrimary (citable) accession number: B4SDS6
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info